Expression and functional role of Bone Morphogenetic Proteins (BMPs) in cyclical corpus luteum in buffalo (Bubalus bubalis)

Highlights • BMPs and their functional receptors are expressed in a regulated manner during different stages of corpus lueum development in buffalo ( Bubalus bubalis ). • BMP4 and BMP7 stimulate luteal cell steroidogenesis. • BMP4 and BMP7 possibly act as cytoprotective factors. Thus, they promote l...

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Bibliographic Details
Published in:	General and comparative endocrinology Vol. 240; pp. 198 - 213
Main Authors:	G.Rajesh, Paul, Avishek, Mishra, SR, Bharati, Jaya, Thakur, Nipuna, Mondal, Tanmay, Soren, Sanjhali, S.Harikumar, K.Narayanan, V.S.Chouhan, Bag, Sadhan, B.C.Das, G.Singh, Maurya, V.P, Sharma, G.Taru, Sarkar, Mihir
Format:	Journal Article
Language:	English
Published:	United States Elsevier Inc 01-01-2017
Subjects:	Animals Apoptosis BMP Bone Morphogenetic Protein Receptors - metabolism Bone Morphogenetic Proteins - genetics Bone Morphogenetic Proteins - metabolism Bubalus bubalis Buffalo Buffaloes - genetics Caspase 3 - genetics Caspase 3 - metabolism Cells, Cultured Corpus luteum Corpus Luteum - metabolism Endocrinology & Metabolism Female Gene Expression Profiling Gene Expression Regulation Immunoblotting Immunohistochemistry Progesterone Progesterone - genetics Progesterone - metabolism Proliferating Cell Nuclear Antigen - metabolism RNA, Messenger - genetics RNA, Messenger - metabolism Time Factors Corpus luteum Progesterone BMP Buffalo
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Summary:	Highlights • BMPs and their functional receptors are expressed in a regulated manner during different stages of corpus lueum development in buffalo ( Bubalus bubalis ). • BMP4 and BMP7 stimulate luteal cell steroidogenesis. • BMP4 and BMP7 possibly act as cytoprotective factors. Thus, they promote luteal cell survival.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0016-6480 1095-6840
DOI:	10.1016/j.ygcen.2016.10.016