Search Results - "Soprano, Samantha"

Identifying Clinically Relevant Drug–Drug Interactions With Methadone and Buprenorphine: A Translational Approach to Signal Detection by Miano, Todd A., Wang, Lei, Leonard, Charles E., Brensinger, Colleen M., Acton, Emily K., Dawwas, Ghadeer K., Bilker, Warren B., Soprano, Samantha E., Nguyen, Thanh Phuong Pham, Woody, George, Yu, Elmer, Neuman, Mark, Li, Lang, Hennessy, Sean

“…Methadone and buprenorphine have pharmacologic properties that are concerning for a high risk of drug–drug interactions (DDIs). We performed high‐throughput…”
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Assessment of Physician Prescribing of Muscle Relaxants in the United States, 2005-2016 by Soprano, Samantha E, Hennessy, Sean, Bilker, Warren B, Leonard, Charles E

“…Little is known to date about national trends in the prescribing of skeletal muscle relaxants (SMRs), the use of which is associated with important safety…”
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Screening to identify signals of opioid drug interactions leading to unintentional traumatic injury by Leonard, Charles E., Brensinger, Colleen M., Pham Nguyen, Thanh Phuong, Horn, John R., Chung, Sophie, Bilker, Warren B., Dublin, Sascha, Soprano, Samantha E., Dawwas, Ghadeer K., Oslin, David W., Wiebe, Douglas J., Hennessy, Sean

“…[Display omitted] •Opioid drug interactions are a high priority target for minimizing patient harms.•We identified potential opioid drug interactions…”
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Comparative Safety of Dipeptidyl Peptidase‐4 Inhibitors and Sudden Cardiac Arrest and Ventricular Arrhythmia: Population‐Based Cohort Studies by Dawwas, Ghadeer K., Hennessy, Sean, Brensinger, Colleen M., Deo, Rajat, Bilker, Warren B., Soprano, Samantha E., Dhopeshwarkar, Neil, Flory, James H., Bloomgarden, Zachary T., Aquilante, Christina L., Kimmel, Stephen E., Leonard, Charles E.

“…In vivo studies suggest that arrhythmia risk may be greater with less selective dipeptidyl peptidase‐4 inhibitors, but evidence from population‐based studies…”
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Skeletal muscle relaxant drug–drug–drug interactions and unintentional traumatic injury: Screening to detect three‐way drug interaction signals by Chen, Cheng, Hennessy, Sean, Brensinger, Colleen M., Dawwas, Ghadeer K., Acton, Emily K., Bilker, Warren B., Chung, Sophie P., Dublin, Sascha, Horn, John R., Miano, Todd A., Pham Nguyen, Thanh Phuong, Soprano, Samantha E., Leonard, Charles E.

“…Aim The aim of this study was to identify skeletal muscle relaxant (SMR) drug–drug–drug interaction (3DI) signals associated with increased rates of…”
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Clopidogrel Drug Interactions and Serious Bleeding: Generating Real‐World Evidence via Automated High‐Throughput Pharmacoepidemiologic Screening by Leonard, Charles E., Zhou, Meijia, Brensinger, Colleen M., Bilker, Warren B., Soprano, Samantha E., Pham Nguyen, Thanh Phuong, Nam, Young Hee, Cohen, Jordana B., Hennessy, Sean

“…Few population‐based studies have examined bleeding associated with clopidogrel drug–drug interactions (DDIs). We sought to identify precipitant drugs taken…”
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Population‐Based Signals of Antidepressant Drug Interactions Associated With Unintentional Traumatic Injury by Leonard, Charles E., Brensinger, Colleen M., Acton, Emily K., Miano, Todd A., Dawwas, Ghadeer K., Horn, John R., Chung, Sophie, Bilker, Warren B., Dublin, Sascha, Soprano, Samantha E., Pham Nguyen, Thanh Phuong, Manis, Melanie M., Oslin, David W., Wiebe, Douglas J., Hennessy, Sean

“…Antidepressants are very widely used and associated with traumatic injury, yet little is known about their potential for harmful drug interactions. We aimed to…”
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Risk of sudden cardiac arrest and ventricular arrhythmia with sulfonylureas: An experience with conceptual replication in two independent populations by Dhopeshwarkar, Neil, Brensinger, Colleen M., Bilker, Warren B., Soprano, Samantha E., Flory, James H., Dawwas, Ghadeer K., Gagne, Joshua J., Hennessy, Sean, Leonard, Charles E.

“…Sulfonylureas are commonly used to treat type 2 diabetes mellitus. Despite awareness of their effects on cardiac physiology, a knowledge gap exists regarding…”
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Population-based signals of benzodiazepine drug interactions associated with unintentional traumatic injury by Pham Nguyen, Thanh Phuong, Soprano, Samantha E., Hennessy, Sean, Brensinger, Colleen M., Bilker, Warren B., Miano, Todd A., Acton, Emily K., Horn, John R., Chung, Sophie P., Dublin, Sascha, Oslin, David W., Wiebe, Douglas J., Leonard, Charles E.

“…Benzodiazepine receptor agonists and related medications, such as Z-drugs and dual orexin receptor antagonists (BZDs), have been associated with unintentional…”
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The risk of sudden cardiac arrest and ventricular arrhythmia with rosiglitazone versus pioglitazone: real-world evidence on thiazolidinedione safety by Leonard, Charles E, Brensinger, Colleen M, Dawwas, Ghadeer K, Deo, Rajat, Bilker, Warren B, Soprano, Samantha E, Dhopeshwarkar, Neil, Flory, James H, Bloomgarden, Zachary T, Gagne, Joshua J, Aquilante, Christina L, Kimmel, Stephen E, Hennessy, Sean

“…The low cost of thiazolidinediones makes them a potentially valuable therapeutic option for the > 300 million economically disadvantaged persons worldwide with…”
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Signals of Muscle Relaxant Drug Interactions Associated with Unintentional Traumatic Injury: A Population-Based Screening Study by Dawwas, Ghadeer K., Hennessy, Sean, Brensinger, Colleen M., Acton, Emily K., Bilker, Warren B., Chung, Sophie, Dublin, Sascha, Horn, John R., Manis, Melanie M., Miano, Todd A., Oslin, David W., Pham Nguyen, Thanh Phuong, Soprano, Samantha E., Wiebe, Douglas J., Leonard, Charles E.

“…Background Use of muscle relaxants is rapidly increasing in the USA. Little is understood about the role of drug interactions in the known association between…”
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Thromboembolic Events in Users of Warfarin Treated with Different Skeletal Muscle Relaxants by Leonard, Charles E, Brensinger, Colleen M, Bilker, Warren B, Soprano, Samantha E, Dhopeshwarkar, Neil, Hecht, Todd E H, Kasner, Scott E, Nutescu, Edith A, Holbrook, Anne, Carr, Matthew, Ashcroft, Darren M, Chen, Cheng, Hennessy, Sean

“…Background and Objectives: Warfarin and a skeletal muscle relaxant are co-treatments in nearly a quarter-million annual United States (US) office visits…”
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Receipt of Substance Use Counseling Among Ambulatory Patients Prescribed Opioids in the United States by Evoy, Kirk E, Leonard, Charles E, Covvey, Jordan R, Ochs, Leslie, Peckham, Alyssa M, Soprano, Samantha, Reveles, Kelly R

“…Background: As opioid-related overdose deaths climb in the U.S., risk reduction measures are increasingly important. One such measure recommended involves…”
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Nuclear Magnetic Resonance and Headspace Solid-Phase Microextraction Gas Chromatography as Complementary Methods for the Analysis of Beer Samples by Johnson, Sarah, Soprano, Samantha, Wickham, Laura, Fitzgerald, Neil, Edwards, John

“…Chemical analysis of the organic components in beer has applications to quality control, authenticity and improvements to the flavor characteristics and…”
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National outpatient medication utilization for opioid and alcohol use disorders from 2014 to 2016 by Evoy, Kirk E., Roccograndi, Laura, Le, Samantha, Leonard, Charles E., Covvey, Jordan R., Ochs, Leslie, Peckham, Alyssa M., Soprano, Samantha E., Reveles, Kelly R.

“…Research has recommended a combination of pharmacotherapy and behavioral therapy to treat opioid use disorder (OUD) or alcohol use disorder (AUD). The…”
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