Search Results - "Sopi, Ramadan B."
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Curcumin analogs (B2BrBC and C66) supplementation attenuates airway hyperreactivity and promote airway relaxation in neonatal rats exposed to hyperoxia
Published in Physiological reports (01-08-2020)“…Background This study was undertaken to test the hypothesis that the newly synthesized curcuminoids B2BrBC and C66 supplementation will overcome…”
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The Role of Insulin Therapy in Correcting Hepcidin Levels in Patients with Type 2 Diabetes Mellitus
Published in Oman medical journal (01-05-2017)“…Objectives: Iron overload can cause or contribute to the pathogenesis of type 2 diabetes mellitus (T2DM), but how the major parameters of iron metabolism…”
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Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction
Published in Cells (Basel, Switzerland) (18-05-2021)“…Expression of bronchodilatory β2-adrenoceptors and bronchoconstrictive muscarinic M3-receptors alter with airway size. In COPD, (a combination of) β2-agonists…”
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4
Insulin treatment corrects hepcidin but not YKL-40 levels in persons with type 2 diabetes mellitus matched by body mass index, waist-to-height ratio, C-reactive protein and Creatinine
Published in BMC endocrine disorders (25-08-2017)“…It has been shown that hepcidin and YKL-40 levels change in persons with insulin resistance in different circumstances. However, variations of the levels of…”
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L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia
Published in Respiratory research (07-08-2012)“…Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a…”
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Quercetin supplementation attenuates airway hyperreactivity and restores airway relaxation in rat pups exposed to hyperoxia
Published in Experimental biology and medicine (Maywood, N.J.) (01-09-2023)“…Hyperoxia exposure of immature lungs contributes to lung injury and airway hyperreactivity. Up to now, treatments of airway hyperreactivity induced by…”
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Rho-kinase inhibitors protect against neonatal hyperoxia-induced airway hyperreactivity in a rat pup model: Role of prostaglandin F 2α
Published in Pediatric pulmonology (01-05-2022)“…Oxygen therapy in preterm neonates is associated with airway hyperreactivity. The role of Rho/Rho-kinase smooth muscle signaling in hyperoxia-induced airway…”
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Rho‐kinase inhibitors protect against neonatal hyperoxia‐induced airway hyperreactivity in a rat pup model: Role of prostaglandin F2α
Published in Pediatric pulmonology (01-05-2022)“…Background Oxygen therapy in preterm neonates is associated with airway hyperreactivity. The role of Rho/Rho‐kinase smooth muscle signaling in…”
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9
Low Hepcidin in Type 2 Diabetes Mellitus: Examining the Molecular Links and Their Clinical Implications
Published in Canadian journal of diabetes (01-04-2018)“…The relationship between iron and glucose metabolism has been evidenced strongly, but the molecular mediation of this connection is just being revealed. The…”
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Protective Effects of Resveratrol Against Airway Hyperreactivity, Oxidative Stress, and Lung Inflammation in a Rat Pup Model of Bronchopulmonary Dysplasia
Published in Physiological research (30-04-2024)“…Oxygen therapy provides an important treatment for preterm and low-birth-weight neonates, however, it has been shown that prolonged exposure to high levels of…”
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Bronchopulmonary Dysplasia and Pulmonary Hypertension: The Role of Smooth Muscle adh5
Published in American journal of respiratory cell and molecular biology (01-07-2021)“…Bronchopulmonary dysplasia (BPD) is characterized by alveolar simplification, airway hyperreactivity and pulmonary hypertension. In our BPD model, we have…”
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Role of arginase in impairing relaxation of lung parenchyma of hyperoxia-exposed neonatal rats
Published in Neonatology (Basel, Switzerland) (01-01-2012)“…Prolonged exposure of immature lungs to hyperoxia contributes to neonatal lung injury and airway hyperreactivity. We have previously demonstrated that neonatal…”
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Bronchodilatory effect of ethanolic extract of the leaves of Nyctanthes arbortristis
Published in Pharmacognosy research (01-07-2013)“…Background: Nyctanthes arbortristis has been used in traditional medicine for the treatment of asthma and cough. Aim: In this study, bronchodilatory effect of…”
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14
Role of brain-derived neurotrophic factor in hyperoxia-induced enhancement of contractility and impairment of relaxation in lung parenchyma
Published in American journal of physiology. Lung cellular and molecular physiology (01-08-2008)“…Prolonged hyperoxic exposure contributes to neonatal lung injury, and airway hyperreactivity is characterized by enhanced contraction and impaired relaxation…”
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Disruption of NO-cGMP signaling by neonatal hyperoxia impairs relaxation of lung parenchyma
Published in American journal of physiology. Lung cellular and molecular physiology (01-10-2007)“…Exposure of immature lungs to hyperoxia for prolonged periods contributes to neonatal lung injury and airway hyperreactivity. We studied the role of disrupted…”
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Role of PGE2‐EP1/EP3 receptor signaling on hyperoxia‐induced airway hyperreactivity in neonatal rats
Published in The FASEB journal (01-04-2017)“…Abstract only Hyperoxic exposure of neonates is followed by airway hyperreactivity, that involves many different molecular signaling mechanisms, including…”
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S‐Nitrosoglutathione Reductase Inhibition Attenuates Long Term Effects of Neonatal Hyperoxia on Airway Hyperreactivity
Published in The FASEB journal (01-04-2020)“…Abstract only Bronchopulmonary dysplasia survivors display long‐term obstructive lung disease with airway hyperreactivity (AHR). While often treated with…”
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S‐Nitrosoglutathione Reductase Inhibition Attenuates Airway Hyperreactivity in a Neonatal Hyperoxia‐Exposed Mouse Model
Published in The FASEB journal (01-04-2019)“…Premature infants exposed to supplemental oxygen are at risk for developing wheezing disorders and airway hyperreactivity (AHR). We have previously shown that…”
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Calcium‐Sensing Receptor (CaSR) Modulates Hyperoxia‐Induced Airway Hyperreactivity In a Neonatal Mouse Model of Bronchopulmonary Dysplasia
Published in The FASEB journal (01-04-2020)“…Abstract only Supplemental O 2 is a primary mode of respiratory therapy for preterm infants. Numerous studies, however, have shown that supplemental O 2 may…”
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Resveratrol Prevents Hyperoxia‐Induced Lung Inflammation
Published in The FASEB journal (01-04-2020)“…Abstract only Prolonged oxygen exposure of preterm infants results in the development of bronchopulmonary dysplasia (BPD), a chronic lung disease characterized…”
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