Search Results - "Sophie Thenet"

Special Issue on the "Regulation and Physiopathology of the Gut Barrier" by Thenet, Sophie, Carrière, Véronique

“…The importance of gut barrier integrity in intestinal homeostasis and the consequences of its alteration in the etiology of human pathologies have been…”
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Increased jejunal permeability in human obesity is revealed by a lipid challenge and is linked to inflammation and type 2 diabetes by Genser, Laurent, Aguanno, Doriane, Soula, Hédi A, Dong, Liping, Trystram, Laurence, Assmann, Karen, Salem, Joe‐Elie, Vaillant, Jean‐Christophe, Oppert, Jean‐Michel, Laugerette, Fabienne, Michalski, Marie‐Caroline, Wind, Philippe, Rousset, Monique, Brot‐Laroche, Edith, Leturque, Armelle, Clément, Karine, Thenet, Sophie, Poitou, Christine

“…Obesity and its metabolic complications are characterized by subclinical systemic and tissue inflammation. In rodent models of obesity, inflammation and…”
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Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12:2, a major quorum-sensing molecule from gut microbiota by Landman, Cécilia, Grill, Jean-Pierre, Mallet, Jean-Maurice, Marteau, Philippe, Humbert, Lydie, Le Balc'h, Eric, Maubert, Marie-Anne, Perez, Kevin, Chaara, Wahiba, Brot, Loic, Beaugerie, Laurent, Sokol, Harry, Thenet, Sophie, Rainteau, Dominique, Seksik, Philippe, Quévrain, Elodie

“…N-acyl homoserine lactones (AHLs), which are autoinducer quorum-sensing molecules involved in the bacterial communication network, also interact with…”
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3-oxo-C12:2-HSL, quorum sensing molecule from human intestinal microbiota, inhibits pro-inflammatory pathways in immune cells via bitter taste receptors by Coquant, Garance, Aguanno, Doriane, Brot, Loïc, Belloir, Christine, Delugeard, Julie, Roger, Nathalie, Pham, Hang-Phuong, Briand, Loïc, Moreau, Marielle, de Sordi, Luisa, Carrière, Véronique, Grill, Jean-Pierre, Thenet, Sophie, Seksik, Philippe

“…In the gut ecosystem, microorganisms regulate group behaviour and interplay with the host via a molecular system called quorum sensing (QS). The QS molecule…”
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The Cellular Prion Protein PrPc Is Involved in the Proliferation of Epithelial Cells and in the Distribution of Junction-Associated Proteins by Morel, Etienne, Fouquet, Stéphane, Strup-Perrot, Carine, Thievend, Cathy Pichol, Petit, Constance, Loew, Damarys, Faussat, Anne-Marie, Yvernault, Lucile, Pinçon-Raymond, Martine, Chambaz, Jean, Rousset, Monique, Thenet, Sophie, Clair, Caroline

“…Background The physiological function of the ubiquitous cellular prion protein, PrPc, is still under debate. It was essentially studied in nervous system, but…”
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Early Loss of E-cadherin from Cell-Cell Contacts Is Involved in the Onset of Anoikis in Enterocytes by Stéphane Fouquet, Verónica-Haydée Lugo-Martínez, Anne-Marie Faussat, Flore Renaud, Philippe Cardot, Jean Chambaz, Martine Pinçon-Raymond, Sophie Thenet

“…Anoikis, i.e. apoptosis induced by detachment from the extracellular matrix, is thought to be involved in the shedding of enterocytes at the tip of intestinal…”
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The cellular prion protein PrP(c) is involved in the proliferation of epithelial cells and in the distribution of junction-associated proteins by Morel, Etienne, Fouquet, Stéphane, Strup-Perrot, Carine, Pichol Thievend, Cathy, Thievend, Cathy Pichol, Petit, Constance, Loew, Damarys, Faussat, Anne-Marie, Yvernault, Lucile, Pinçon-Raymond, Martine, Chambaz, Jean, Rousset, Monique, Thenet, Sophie, Clair, Caroline

“…The physiological function of the ubiquitous cellular prion protein, PrP(c), is still under debate. It was essentially studied in nervous system, but poorly…”
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Epidermal growth factor receptor is involved in enterocyte anoikis through the dismantling of E-cadherin-mediated junctions by Lugo-Martínez, Verónica-Haydée, Petit, Constance S, Fouquet, Stéphane, Le Beyec, Johanne, Chambaz, Jean, Pinçon-Raymond, Martine, Cardot, Philippe, Thenet, Sophie

“…Enterocytes of the intestinal epithelium are continually regenerated. They arise from precursor cells in crypts, migrate along villi, and finally die, 3-4 days…”
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Integrin-mediated functional polarization of Caco-2 cells through E-cadherin--actin complexes by Schreider, Cyrille, Peignon, Gregory, Thenet, Sophie, Chambaz, Jean, Pinçon-Raymond, Martine

“…Enterocyte differentiation is a dynamic process during which reinforcement of cell-cell adhesion favours migration along the crypt-to-villus axis. Functional…”
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Palmitic acid damages gut epithelium integrity and initiates inflammatory cytokine production by Ghezzal, Sara, Postal, Barbara Graziela, Quevrain, Elodie, Brot, Loic, Seksik, Philippe, Leturque, Armelle, Thenet, Sophie, Carrière, Véronique

“…The mechanisms leading to the low-grade inflammation observed during obesity are not fully understood. Seeking the initiating events, we tested the hypothesis…”
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E-cadherin-dependent Transcriptional Control of Apolipoprotein A-IV Gene Expression in Intestinal Epithelial Cells by Peignon, Gregory, Thenet, Sophie, Schreider, Cyrille, Fouquet, Stéphane, Ribeiro, Agnès, Dussaulx, Elizabeth, Chambaz, Jean, Cardot, Philippe, Pinçon-Raymond, Martine, Le Beyec, Johanne

“…Cell-matrix and cell-cell adhesion play a central role in the control of cell proliferation, differentiation, and gene expression. Integrins and E-cadherin are…”
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Gossip in the gut: Quorum sensing, a new player in the host-microbiota interactions by Coquant, Garance, Aguanno, Doriane, Pham, Sandrine, Grellier, Nathan, Thenet, Sophie, Carrière, Véronique, Grill, Jean-Pierre, Seksik, Philippe

“…Bacteria are known to communicate with each other and regulate their activities in social networks by secreting and sensing signaling molecules called…”
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Use of Ussing Chambers to Measure Paracellular Permeability to Macromolecules in Mouse Intestine by Aguanno, Doriane, Postal, Bárbara Graziela, Carrière, Véronique, Thenet, Sophie

“…An increased intestinal permeability has been described in many diseases including inflammatory bowel disease and metabolic disorders, and a better…”
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Rapid Evaluation of Intestinal Paracellular Permeability Using the Human Enterocytic-Like Caco-2/TC7 Cell Line by Postal, Bárbara Graziela, Aguanno, Doriane, Thenet, Sophie, Carrière, Véronique

“…Paracellular permeability of the intestinal epithelium is a feature of the intestinal barrier, which plays an important role in the physiology of gut and the…”
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Serum Versus Fecal Calprotectin Levels in Patients with Severe Obesity Before and 6 Months After Roux-Y-Gastric Bypass: Report of the Prospective Leaky-Gut Study by Serrano, Ella, Bastard, Jean-Philippe, Trystram, Laurence, Fellahi, Soraya, Soula, Hedi A., Thenet, Sophie, Oppert, Jean-Michel, Clément, Karine, Poitou, Christine, Genser, Laurent

“…Introduction Obesity is associated with low-grade inflammation, including intestinal inflammation based on fecal or serum calprotectin (FC-SC) measurement…”
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The nucleo-junctional interplay of the cellular prion protein: A new partner in cancer-related signaling pathways? by Rousset, Monique, Leturque, Armelle, Thenet, Sophie

“…The cellular prion protein PrP c plays important roles in proliferation, cell death and survival, differentiation and adhesion. The participation of PrP c in…”
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Intestinal plasticity in response to nutrition and gastrointestinal surgery by Le Gall, Maude, Thenet, Sophie, Aguanno, Doriane, Jarry, Anne-Charlotte, Genser, Laurent, Ribeiro-Parenti, Lara, Joly, Francisca, Ledoux, Séverine, Bado, André, Le Beyec, Johanne

“…The plasticity of a material corresponds to its capacity to change its feature under the effect of an external action. Intestinal plasticity could be defined…”
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Mo1113 – 3-Oxo-C12:2 N-Acyl Homoserine Lactone, a Quorum Sensing Molecule from the Gut Microbiota: A New Player to Control Gut Inflammation by Aguanno, Doriane, Coquant, Garance, Peyrottes, Agathe, Landman, Cecilia, Brot, Loic, Mallet, Jean-Maurice, Quevrain, Elodie, Carriere, Veronique, Osinski, Celine, Leturque, Armelle, Seksik, Philippe, Grill, Jean-Pierre, Thenet, Sophie

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The cellular prion protein PrPc is a partner of the Wnt pathway in intestinal epithelial cells by Besnier, Laura S, Cardot, Philippe, Da Rocha, Barbara, Simon, Anthony, Loew, Damarys, Klein, Christophe, Riveau, Béatrice, Lacasa, Michel, Clair, Caroline, Rousset, Monique, Thenet, Sophie

“…We reported previously that the cellular prion protein (PrP(c)) is a component of desmosomes and contributes to the intestinal barrier function. We…”
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The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption by Aguanno, Doriane, Coquant, Garance, Postal, Barbara G., Osinski, Céline, Wieckowski, Margaux, Stockholm, Daniel, Grill, Jean-Pierre, Carrière, Véronique, Seksik, Philippe, Thenet, Sophie

“…The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major actors…”
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