Search Results - "Soozangar, Narges"
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1
An update of Nrf2 activators and inhibitors in cancer prevention/promotion
Published in Cell communication and signaling (30-06-2022)“…Abstract NF-E2-related factor 2 (Nrf2) protein is a basic-region leucine zipper transcription factor that defends against endogenous or exogenous stressors. By…”
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2
Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance
Published in DNA repair (01-06-2017)“…•Nrf2 exerts cancer-preventive activity through induction of cytoprotective genes.•Under a deleterious environment, Nrf2 elevates the survival rate of tumor…”
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3
The common bisulfite-conversion-based techniques to analyze DNA methylation in human cancers
Published in Cancer cell international (09-07-2024)“…DNA methylation is an important molecular modification that plays a key role in the expression of cancer genes. Evaluation of epigenetic changes,…”
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4
The role of Nrf2-Keap1 axis in colorectal cancer, progression, and chemoresistance
Published in Tumor Biology (01-06-2017)“…Colorectal cancer is the third common cancer after lung and genital cancers worldwide with more than 1.2 million new cases diagnosed annually. Although…”
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Book Review Journal Article -
5
Comparison of genome‐wide analysis techniques to DNA methylation analysis in human cancer
Published in Journal of cellular physiology (01-05-2018)“…DNA methylation was the first epigenetic modification to be detected in human cancers with specific relation to aberrant gene expression. Herein, DNA…”
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6
The interplay between microRNAs and Nrf2 signaling in human cancers
Published in Cancer cell international (05-07-2024)“…MicroRNAs (miRNAs), as a class of nonprotein-coding RNAs, post-transcriptionally regulate the expression of target genes by base pairing to 3'-untranslated…”
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7
A novel compound heterozygous of β-thalassemia with HbG-Coushatta: case report of Iran
Published in Human genome variation (15-05-2023)“…A 30-year-old male couple from Ardabil city, Iran, were admitted for premarital screening. An abnormal band in HbS/D regions with high levels of HbF and HbA 2…”
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8
The role of Nrf2 signaling in parasitic diseases and its therapeutic potential
Published in Heliyon (30-06-2024)“…In response to invading parasites, one of the principal arms of innate immunity is oxidative stress, caused by reactive oxygen species (ROS). However,…”
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Hydatid Cyst Protoscolices Induce Cell Death in WEHI-164 Fibrosarcoma Cells and Inhibit the Proliferation of Baby Hamster Kidney Fibroblasts In Vitro
Published in Journal of Parasitology Research (2012)“…Both in vitro and in vivo models have demonstrated that some parasites can interfere with tumor cell growth. The present study investigates the anticancer…”
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10
Cellular immunotherapy in gastric cancer: adoptive cell therapy and dendritic cell-based vaccination
Published in Immunotherapy (01-04-2022)“…Gastric cancer (GC) is one of the most frequently diagnosed malignancies. Recent studies have highlighted cellular immunotherapy (CI) as a promising approach…”
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11
The suppressive effects of crocin from saffron on allergic airway inflammation through Drp1/Nfr1/Mfn2/Pgc1-alpha signaling pathway in mice
Published in Journal of ethnopharmacology (30-01-2025)“…Saffron is derived from the dried stigmas of Crocus sativus L., which was considered by ancient nations for food and medicinal purposes. In traditional…”
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12
Nrf2/P–glycoprotein axis is associated with clinicopathological characteristics in colorectal cancer
Published in Biomedicine & pharmacotherapy (01-08-2018)“…[Display omitted] •In colorectal cancer patients there is an over- expression of Nrf2 and ABCB1/P–gp compared to non colorectal individuals.•There is a…”
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13
Nrf2 overexpression is associated with P-glycoprotein upregulation in gastric cancer
Published in Biomedicine & pharmacotherapy (01-01-2018)“…The efficacy of chemotherapeutic agents remains very poor in gastric cancer (GC) patients due to the development of multidrug resistance (MDR) phenotype. The…”
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14
In vitro Evaluation of the Potent Antileishmanial Activity of Ferula tabasensis Alone or in Combination with Shark Cartilage Extract Against the Standard Iranian Strain of Leishmania major (MRHO/IR/75/ER)
Published in Iranian journal of pharmaceutical research : IJPR (01-12-2023)“…Background: The available drugs for the treatment of leishmaniasis are highly toxic and extremely expensive, with low efficiency; therefore, the development of…”
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15
The roles of miR-383 as a diagnostic and prognostic biomarker in human cancers
Published in Gene reports (01-09-2024)“…Emerging evidence indicates that Long non-coding RNAs (LncRNAs) and microRNAs (miRNAs) play crucial roles in the biology of cancerous cells. MicroRNAs are…”
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Biomimetic synthesis of silver nanoparticles using Matricaria chamomilla extract and their potential anticancer activity against human lung cancer cells
Published in Materials Science & Engineering C (01-11-2018)“…Herbs having various natural substances can be utilized for the biosynthesis of Silver nanoparticles (AgNPs) and act as a stable, reliable and biocompatible…”
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17
Reduced Levels of miR-28 and miR-200a Act as Predictor Biomarkers of Aggressive Clinicopathological Characteristics in Gastric Cancer Patients
Published in Galen (25-01-2019)“…MicroRNAs (miRNAs) play critical roles in different pathological processes including cancer development and progression. To find novel molecular diagnostic and…”
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Reduced Levels of miR–28 and miR–200a Act as Predictor Biomarkers of Aggressive Clinicopathological Characteristics in Gastric Cancer Patients
Published in Galen (25-01-2019)“…Background: MicroRNAs (miRNAs) play critical roles in different pathological processes including cancer development and progression. To find novel molecular…”
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