Search Results - "Soon, Gaik Hong"

Randomized trial comparing effects of weight loss by liraglutide with lifestyle modification in non‐alcoholic fatty liver disease by Khoo, Joan, Hsiang, John C., Taneja, Ranu, Koo, Seok‐Hwee, Soon, Gaik‐Hong, Kam, Carmen J., Law, Ngai‐Moh, Ang, Tiing‐Leong

“…Background & Aims We compared the effects of weight loss induced with the glucagon‐like peptide‐1 agonist liraglutide, with that of lifestyle modification,…”
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Clinical trial: seven‐day vonoprazan‐ versus 14‐day proton pump inhibitor‐based triple therapy for first‐line Helicobacter pylori eradication by Ang, Daphne, Koo, Seok Hwee, Chan, Yiong Huak, Tan, Thean Yen, Soon, Gaik Hong, Tan, Chin Kimg, Lin, Kenneth Weicong, Krishnasamy‐Balasubramanian, Jaydeesh‐Khanna, Wong, Yu Jun, Kumar, Rahul, R, Rajesh, Tan, Yiyuan, Ong, Peng‐Lan Jeannie, Tan, Yi‐Lyn Jessica, Li, James Weiquan, Kwek, Andrew Boon‐Eu, Ang, Tiing Leong

“…Summary Background One‐week triple therapy with vonoprazan is endorsed by Japanese guidelines as an alternative to proton pump inhibitor (PPI)‐based triple…”
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Population pharmacokinetic analysis of isoniazid, acetylisoniazid, and isonicotinic acid in healthy volunteers by Seng, Kok-Yong, Hee, Kim-Hor, Soon, Gaik-Hong, Chew, Nicholas, Khoo, Saye H, Lee, Lawrence Soon-U

“…In this study, we aimed to quantify the effects of the N-acetyltransferase 2 (NAT2) phenotype on isoniazid (INH) metabolism in vivo and identify other sources…”
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Population pharmacokinetics of rifampicin and 25-deacetyl-rifampicin in healthy Asian adults by Seng, Kok-Yong, Hee, Kim-Hor, Soon, Gaik-Hong, Chew, Nicholas, Khoo, Saye H, Lee, Lawrence Soon-U

“…Rifampicin is a first-line anti-TB drug. The objectives of this analysis were to evaluate the population pharmacokinetics of rifampicin and its partly active…”
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Pharmacokinetic Modeling of Plasma and Intracellular Concentrations of Raltegravir in Healthy Volunteers by Wang, Lingzhi, Soon, Gaik Hong, Seng, Kok-Yong, Li, Jun, Lee, Edmund, Yong, Eu-Leong, Goh, Boon-Cher, Flexner, Charles, Lee, Lawrence

“…Raltegravir is a potent inhibitor of HIV integrase. Persistently high intracellular concentrations of raltegravir may explain sustained efficacy despite high…”
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A pilot study to examine the association between human gut microbiota and the host's central obesity by Koo, Seok Hwee, Chu, Collins Wenhan, Khoo, Joan Joo Ching, Cheong, Magdalin, Soon, Gaik Hong, Ho, Eliza Xin Pei, Law, Ngai Moh, De Sessions, Paola Florez, Fock, Kwong Ming, Ang, Tiing Leong, Lee, Edmund Jon Deoon, Hsiang, John Chen

“…Background and Aim Perturbance in the composition of human gut microbiota has been associated with metabolic disorders such as obesity, diabetes mellitus, and…”
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Simultaneous determination of raltegravir and raltegravir glucuronide in human plasma by liquid chromatography-tandem mass spectrometric method by Wang, Ling-Zhi, Lee, Lawrence Soon -U, Thuya, Win-Lwin, Soon, Gaik Hong, Kong, Li-Ren, Nye, Pei-Ling, Deoon Lee, Edmund Jon, Flexner, Charles, Goh, Boon-Cher

“…Raltegravir is a highly efficacious inhibitor of HIV integrase. Large pharmacokinetic variability has been reported in clinical trials and this could be due to…”
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Evaluation of a six-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam, and digoxin) approach to estimate hepatic drug detoxification capability and dosage requirements after a single oral dosing in healthy Chinese volunteers by Koo, Seok Hwee, Soon, Gaik Hong, Pruvost, Alain, Benech, Henri, Ang, Tiing Leong, Lee, Edmund Jon Deoon, Ang, Daphne Shih Wen

“…The primary objectives of this study were to investigate the suitability of a 6-probe cocktail (caffeine, tolbutamide, omeprazole, dextromethorphan, midazolam,…”
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CYP3A53 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients by Seng, Kok-Yong, Hee, Kim-Hor, Soon, Gaik Hong, Sapari, Nur Sabrina, Soong, Richie, Goh, Boon-Cher, Lee, Lawrence Soon-U

“…We aim to evaluate the influence of covariates, including cytochrome P450 3A (CYP3A) genetic polymorphisms, on the pharmacokinetics of midazolam (MDZ) in Asian…”
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CYP3A53 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients: The Journal of Clinical Pharmacology by Seng, Kok-Yong, Hee, Kim-Hor, Soon, Gaik Hong, Sapari, Nur Sabrina, Soong, Richie, Goh, Boon-Cher, Lee, Lawrence Soon-U

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Inter-ethnic differences in efavirenz CNS toxicity – role of cytochrome P450 2B6 polymorphisms by Lee, Lawrence S, Soon, Gaik Hong, Teo, Yik Ying

“…Doc number: O17…”
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