Search Results - "Soomro, Irshad"

Barrett's dysplasia and the Vienna classification: reproducibility, prediction of progression and impact of consensus reporting and p53 immunohistochemistry by Kaye, Philip V, Haider, Syeda A, Ilyas, Mohammed, James, Peter D, Soomro, Irshad, Faisal, Wasek, Catton, James, Parsons, Simon L, Ragunath, Krish

“…Aims:  The Vienna classification is used to classify dysplasia in Barrett’s oesophagus (BO), but reproducibility and value of diagnosis of lower grades in…”
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BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas by Bari, Muhammad F, Brown, Helen, Nicholson, Andrew G, Kerr, Keith M, Gosney, John R, Wallace, William A, Soomro, Irshad, Muller, Salli, Peat, Danielle, Moore, Jonathan D, Ward, Lesley A, Freidin, Maxim B, Lim, Eric, Vatish, Manu, Snead, David R J

“…Aims Discriminating small‐cell lung carcinoma (SCLC) from large‐cell neuroendocrine carcinoma (LCNEC) rests on morphological criteria, and reproducibility has…”
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Primary lymphoma arising in a mature cystic teratoma of the ovary by Gandhi, Nirav, Soomro, Irshad N, O'Connor, Simon, Sovani, Vishakha

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Evolution of lung pathology in lymphangioleiomyomatosis: associations with disease course and treatment response by Miller, Suzanne, Stewart, Iain D, Clements, Debbie, Soomro, Irshad, Babaei‐Jadidi, Roya, Johnson, Simon R

“…Lymphangioleiomyomatosis (LAM) is a rare multisystem disease with a variable clinical course. The lungs are infiltrated by nodules of LAM cells, stromal cells…”
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Primary Esophagogastric Neuroendocrine Carcinoma: a Retrospective Study from the Nottingham Upper Gastrointestinal Cancer Center by Savva, Constantinos, Kaye, Philip, Soomro, Irshad, Parsons, Simon L., James, Eleanor, Madhusudan, Srinivasan

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Stratification of resectable lung adenocarcinoma by molecular and pathological risk estimators by Rakha, Emad, Pajares, Maria J, Ilie, Marius, Pio, Ruben, Echeveste, Jose, Hughes, Elisha, Soomro, Irshad, Long, Elodie, Idoate, Miguel A, Wagner, Susanne, Lanchbury, Jerry S, Baldwin, David R, Hofman, Paul, Montuenga, Luis M

“…Abstract Background Mortality in early stage, resectable lung cancer is sufficiently high to warrant consideration of post-surgical treatment. Novel markers to…”
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Are DNA repair factors promising biomarkers for personalized therapy in gastric cancer? by Abdel-Fatah, Tarek, Arora, Arvind, Gorguc, Ipek, Abbotts, Rachel, Beebeejaun, Sarah, Storr, Sarah, Mohan, Vivek, Hawkes, Claire, Soomro, Irshad, Lobo, Dileep N, Parsons, Simon L, Madhusudan, Srinivasan

“…Chronic inflammation is a driving force for gastric carcinogenesis. Reactive oxygen species (ROS) generated during the inflammatory process generates DNA…”
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Tumour regression grade (TRG) analyses in patients with resectable gastro-oesophageal adenocarcinomas treated with platinum-based neoadjuvant chemotherapy by Fareed, Khaleel R, Ilyas, Mohammad, Kaye, Philip V, Soomro, Irshad N, Lobo, Dileep N, Parsons, Simon L, Madhusudan, Srinivasan

“…Aims:  Neoadjuvant chemotherapy followed by surgery is the standard of care for patients with gastro‐oesophageal adenocarcinoma. The aims were to validate the…”
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Thioredoxin interacting protein and its association with clinical outcome in gastro-oesophageal adenocarcinoma by Woolston, Caroline M, Madhusudan, Srinivasan, Soomro, Irshad N, Lobo, Dileep N, Reece-Smith, Alexander M, Parsons, Simon L, Martin, Stewart G

“…The overall prognosis for operable gastro-oesophageal adenocarcinoma remains poor and therefore neoadjuvant chemotherapy has become the standard of care, in…”
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Caspase-cleaved cytokeratin-18 and tumour regression in gastro-oesophageal adenocarcinomas treated with neoadjuvant chemotherapy by Fareed, Khaleel R, Soomro, Irshad N, Hameed, Khalid, Arora, Arvind, Lobo, Dileep N, Parsons, Simon L, Madhusudan, Srinivasan

“…AIM：To examine cytokeratin-18（CK-18） and caspasecleaved CK-18 expression in tumours and correlate with clinicopathological outcomes including tumour regression…”
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A multicentre cohort study to redefine and validate pathological assessment of response to neoadjuvant therapy in treated oesophagogastric adenocarcinoma by Lloyd, Megan A, Noble, Fergus, Walker, Rob, McManus, Damien, Turkington, Richard, Bedford, Matt, Griffiths, Ewen, Whiting, John, Nutzinger, Barbara, Grehan, Nicola, Robert O'Neill, J, Skipworth, Richard J.E, Save, Vicki, Rupesh, Sutaria, Mercer, Stuart, Saunders, John H, Soomro, Irshad N, Parsons, Simon L, Fitzgerald, Rebecca C, Underwood, Timothy J

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Prevention is better than Cure - Healthcare Systems in United Kingdom and Pakistan by Soomro, Irshad Nabi

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Prevention is better than Cure - Healthcare Systems in United Kingdom and Pakistan by Soomro, Irshad Nabi

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Pathology of thymoma-where are we today? by Soomro, Irshad Nabi

“…Thymoma is the commonest epithelial neoplasm arising from thymus gland. Tumour is slow growing and in the absence of metastasis, surgery is the treatment of…”
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Histological determinants of survival in completely resected T1-2N1M0 nonsmall cell cancer of the lung by Khan, Omar A, Fitzgerald, James J, Field, Mark L, Soomro, Irshad, Beggs, F.David, Morgan, W.Ellis, Duffy, John P

“…The histologic determinants of survival after surgical resection of stage II nonsmall cell lung cancer are poorly understood. We analyzed the prognostic…”
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Low-dose methotrexate is ineffective in primary biliary cirrhosis: Long-term results of a placebo-controlled trial by Hendrickse, Mark T., Rigney, Elizabeth, Giaffer, Mustapha H., Soomro, Irshad, Triger, David R., Underwood, James C.E., Gleeson, Dermot

“…Background & Aims: New treatments for primary biliary cirrhosis (PBC) need to be evaluated. We conducted a single-center double-blind, randomized trial of…”
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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance by Secrier, Maria, Li, Xiaodun, de Silva, Nadeera, Eldridge, Matthew D, Contino, Gianmarco, Bornschein, Jan, MacRae, Shona, Grehan, Nicola, O'Donovan, Maria, Miremadi, Ahmad, Yang, Tsun-Po, Bower, Lawrence, Chettouh, Hamza, Crawte, Jason, Galeano-Dalmau, Núria, Grabowska, Anna, Saunders, John, Underwood, Tim, Waddell, Nicola, Barbour, Andrew P, Nutzinger, Barbara, Achilleos, Achilleas, Edwards, Paul A W, Lynch, Andy G, Tavaré, Simon, Fitzgerald, Rebecca C

“…Rebecca Fitzgerald and colleagues report the whole-genome sequences of 129 esophageal adenocarcinomas, showing frequent copy number alterations and prevalent…”
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Unveiling the path to sustainable poverty alleviation in Pakistan: Investigating the role of microfinance interventions in empowering women entrepreneurs by Farooq, Syed Hamza, Din, Arif Ud, Soomro, Irshad Ahmed, Riviezzo, Angelo

“…Unsustainability and the menace of poverty are the major challenges confronted by developing countries like Pakistan. This study intends to highlight the…”
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The landscape of selection in 551 esophageal adenocarcinomas defines genomic biomarkers for the clinic by Frankell, Alexander M., Jammula, SriGanesh, Li, Xiaodun, Contino, Gianmarco, Killcoyne, Sarah, Abbas, Sujath, Perner, Juliane, Bower, Lawrence, Devonshire, Ginny, Ococks, Emma, Grehan, Nicola, Mok, James, O’Donovan, Maria, MacRae, Shona, Eldridge, Matthew D., Tavaré, Simon, Fitzgerald, Rebecca C.

“…Esophageal adenocarcinoma (EAC) is a poor-prognosis cancer type with rapidly rising incidence. Understanding of the genetic events driving EAC development is…”
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Whole-genome sequencing provides new insights into the clonal architecture of Barrett's esophagus and esophageal adenocarcinoma by Ross-Innes, Caryn S, Becq, Jennifer, Warren, Andrew, Cheetham, R Keira, Northen, Helen, O'Donovan, Maria, Malhotra, Shalini, di Pietro, Massimiliano, Ivakhno, Sergii, He, Miao, Weaver, Jamie M J, Lynch, Andy G, Kingsbury, Zoya, Ross, Mark, Humphray, Sean, Bentley, David, Fitzgerald, Rebecca C

“…Rebecca Fitzgerald and colleagues report whole-genome sequence analyses of 23 paired samples of Barrett's esophagus and esophageal adenocarcinoma. Their…”
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