Search Results - "Soo‐Beng Khoo, Alan"
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1
Inhibition of breast cancer xenografts in a mouse model and the induction of apoptosis in multiple breast cancer cell lines by lactoferricin B peptide
Published in Journal of cellular and molecular medicine (01-08-2021)“…Breast cancer has a diverse aetiology characterized by the heterogeneous expression of hormone receptors and signalling molecules, resulting in varied…”
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2
A novel and non‐invasive approach utilising nasal washings for the detection of nasopharyngeal carcinoma
Published in International journal of cancer (15-10-2019)“…Nasopharyngeal carcinoma (NPC) is an epithelial cancer of the nasopharynx which is highly associated with Epstein–Barr virus (EBV). Worldwide, most of the top…”
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3
Dielectrophoretic deformation of breast cancer cells for lab on a chip applications
Published in Electrophoresis (01-10-2019)“…This paper presents the development and experimental analysis of a curved microelectrode platform for the DEP deformation of breast cancer cells (MDA‐MB‐231)…”
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4
Nasopharyngeal carcinoma in adolescent patients: A case series
Published in Clinical otolaryngology (01-05-2022)Get full text
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5
Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma
Published in International journal of molecular sciences (20-01-2022)“…c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family members integrate signals that affect proliferation, differentiation,…”
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6
Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review
Published in Journal of Tropical Medicine (01-01-2016)“…Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad…”
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7
Systematic comparison of plasma EBV DNA, anti‐EBV antibodies and miRNA levels for early detection and prognosis of nasopharyngeal carcinoma
Published in International journal of cancer (15-04-2020)“…Nasopharyngeal carcinoma (NPC) is originated from the epithelial cells of nasopharynx, Epstein–Barr virus (EBV)‐associated and has the highest incidence and…”
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8
Epstein-Barr virus Latent Membrane Protein LMP1 reduces p53 protein levels independent of the PI3K-Akt pathway
Published in BMC research notes (21-12-2011)“…Nasopharyngeal carcinoma (NPC) is an epithelial malignancy, which commonly occurs in Southern China, Taiwan, North Africa and Southeast Asia. Nasopharyngeal…”
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9
Pathogenic Role of Exosomes in Epstein-Barr Virus (EBV)-Associated Cancers
Published in International journal of biological sciences (01-01-2017)“…Exosomes are 40- to 100-nm membrane-bound small vesicles that carry a great variety of cellular cargoes including proteins, DNA, messenger RNAs (mRNAs), and…”
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10
Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene
Published in Scientific reports (13-07-2021)“…Epstein-Barr virus (EBV) has been recently found to generate novel circular RNAs (circRNAs) through backsplicing. However, comprehensive catalogs of EBV…”
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11
Dielectrophoresis-based microfluidic platforms for cancer diagnostics
Published in Biomicrofluidics (01-01-2018)“…The recent advancement of dielectrophoresis (DEP)-enabled microfluidic platforms is opening new opportunities for potential use in cancer disease diagnostics…”
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12
Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma
Published in PloS one (01-01-2018)“…Copper(II) ternary complex, [Cu(phen)(C-dmg)(H2O)]NO3 was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma…”
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13
A Cell Internalizing Antibody Targeting Capsid Protein (p24) Inhibits the Replication of HIV-1 in T Cells Lines and PBMCs: A Proof of Concept Study
Published in PloS one (07-01-2016)“…There remains a need for newer therapeutic approaches to combat HIV/AIDS. Viral capsid protein p24 plays important roles in HIV pathogenesis. Peptides and…”
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14
Development of a luciferase/luciferin cell proliferation (XenoLuc) assay for real-time measurements of Gfp-Luc2-modified cells in a co-culture system
Published in BMC biotechnology (14-06-2019)“…In vitro modelling of cancer cells is becoming more complex due to prevailing evidence of intimate interactions between cancer cells and their surrounding…”
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15
Down-regulation of LPA receptor 5 contributes to aberrant LPA signalling in EBV-associated nasopharyngeal carcinoma
Published in The Journal of pathology (01-02-2015)“…Undifferentiated nasopharyngeal carcinoma (NPC) is a highly metastatic disease that is consistently associated with Epstein–Barr virus (EBV) infection. In this…”
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16
Deregulation of lipid metabolism pathway genes in nasopharyngeal carcinoma cells
Published in Molecular medicine reports (01-03-2013)“…Nasopharyngeal carcinoma (NPC) is a unique tumour of epithelial origin with a distinct geographical distribution, closely associated with the Epstein-Barr…”
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17
Exosomes in Human Immunodeficiency Virus Type I Pathogenesis: Threat or Opportunity?
Published in Advances in virology (01-01-2016)“…Nanometre-sized vesicles, also known as exosomes, are derived from endosomes of diverse cell types and present in multiple biological fluids. Depending on…”
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18
Oxidative stress-induced chromosome breaks within the ABL gene: a model for chromosome rearrangement in nasopharyngeal carcinoma
Published in Human genomics (18-06-2018)“…The mechanism underlying chromosome rearrangement in nasopharyngeal carcinoma (NPC) remains elusive. It is known that most of the aetiological factors of NPC…”
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19
Application of champedak mannose-binding lectin in the glycoproteomic profiling of serum samples unmasks reduced expression of alpha-2 macroglobulin and complement factor B in patients with nasopharyngeal carcinoma
Published in Electrophoresis (01-07-2010)“…The use of lectin affinity chromatography prior to 2-DE separation forms an alternative method to unmask the expression of targeted glycoproteins of lower…”
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20
Oncogenic effects of WNT5A in Epstein-Barr virus-associated nasopharyngeal carcinoma
Published in International journal of oncology (01-05-2014)“…The molecular events that drive the progression of Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) are still to be elucidated. Here, we…”
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