Search Results - "Soo, Alan"

Functional Roles of JNK and p38 MAPK Signaling in Nasopharyngeal Carcinoma by Pua, Lesley Jia Wei, Mai, Chun-Wai, Chung, Felicia Fei-Lei, Khoo, Alan Soo-Beng, Leong, Chee-Onn, Lim, Wei-Meng, Hii, Ling-Wei

“…c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (MAPK) family members integrate signals that affect proliferation, differentiation,…”
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Inhibition of breast cancer xenografts in a mouse model and the induction of apoptosis in multiple breast cancer cell lines by lactoferricin B peptide by Rahman, Rizdwan, Fonseka, Alyssa Danielle, Sua, Shiang‐Chia, Ahmad, Munirah, Rajendran, Ramkumar, Ambu, Stephen, Davamani, Fabian, Khoo, Alan Soo‐Beng, Chitra, Ebenezer

“…Breast cancer has a diverse aetiology characterized by the heterogeneous expression of hormone receptors and signalling molecules, resulting in varied…”
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A novel and non‐invasive approach utilising nasal washings for the detection of nasopharyngeal carcinoma by Tan, Geok Wee, Sivanesan, Vijaya Mohan, Abdul Rahman, Farah Ida, Hassan, Faridah, Hasbullah, Harissa Husainy, Ng, Ching‐Ching, Khoo, Alan Soo‐Beng, Tan, Lu Ping

“…Nasopharyngeal carcinoma (NPC) is an epithelial cancer of the nasopharynx which is highly associated with Epstein–Barr virus (EBV). Worldwide, most of the top…”
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Antibacterial Action of Curcumin against Staphylococcus aureus: A Brief Review by Khoo, Alan Soo-Beng, Ali, Syed A., Liew, Kitson, Teow, Sin-Yeang, Peh, Suat-Cheng

“…Curcumin, the major constituent of Curcuma longa L. (Zingiberaceae family) or turmeric, commonly used for cooking in Asian cuisine, is known to possess a broad…”
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Metabolic regulation of the tumour and its microenvironment: The role of Epstein-Barr virus by Lee, Shen-Han, Khoo, Alan Soo-Beng, Griffiths, John R, Mat Lazim, Norhafiza

“…The Epstein-Barr virus (EBV), the first identified human tumour virus, infects over 95% of the individuals globally and has the potential to induce different…”
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Systematic comparison of plasma EBV DNA, anti‐EBV antibodies and miRNA levels for early detection and prognosis of nasopharyngeal carcinoma by Tan, Lu Ping, Tan, Geok Wee, Sivanesan, Vijaya Mohan, Goh, Siang Ling, Ng, Xun Jin, Lim, Chun Shen, Kim, Wee Ric, Mohidin, Taznim Begam Binti Mohd, Mohd Dali, Nor Soleha, Ong, Siew Hoon, Wong, Chun Ying, Sawali, Halimuddin, Yap, Yoke Yeow, Hassan, Faridah, Pua, Kin Choo, Koay, Cheng Eng, Ng, Ching Ching, Khoo, Alan Soo‐Beng

“…Nasopharyngeal carcinoma (NPC) is originated from the epithelial cells of nasopharynx, Epstein–Barr virus (EBV)‐associated and has the highest incidence and…”
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Pathogenic Role of Exosomes in Epstein-Barr Virus (EBV)-Associated Cancers by Teow, Sin-Yeang, Liew, Kitson, Khoo, Alan Soo-Beng, Peh, Suat-Cheng

“…Exosomes are 40- to 100-nm membrane-bound small vesicles that carry a great variety of cellular cargoes including proteins, DNA, messenger RNAs (mRNAs), and…”
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Cytotoxic Activity of Boesenbergia rotunda Extracts against Nasopharyngeal Carcinoma Cells (HK1). Cardamonin, a Boesenbergia rotunda Constituent, Inhibits Growth and Migration of HK1 Cells by Inducing Caspase-Dependent Apoptosis and G2/M-Phase Arrest by Break, Mohammed Khaled Bin, Chiang, Michelle, Wiart, Christophe, Chin, Chiew-Foan, Khoo, Alan Soo Beng, Khoo, Teng-Jin

“…Boesenbergia rotunda (L.) Mansf. is an edible herb that is commonly used in the cuisine of several Asian countries. Studies have shown that it possesses high…”
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Current Status and Future Perspectives about Molecular Biomarkers of Nasopharyngeal Carcinoma by Siak, Pui Yan, Khoo, Alan Soo-Beng, Leong, Chee Onn, Hoh, Boon-Peng, Cheah, Shiau-Chuen

“…Nasopharyngeal carcinoma (NPC) is an epithelial malignancy that shows a remarkable ethnic and geographical distribution. It is one of the major public health…”
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6-Shogaol inhibits breast and colon cancer cell proliferation through activation of peroxisomal proliferator activated receptor γ (PPARγ) by Tan, Boon Shing, Kang, Owen, Mai, Chun Wai, Tiong, Kai Hung, Khoo, Alan Soo-Beng, Pichika, Mallikarjuna Rao, Bradshaw, Tracey D, Leong, Chee-Onn

“…Highlights • 6-shogaol induced gene expression signatures characteristic of PPARg agonists. • 6-shogaol is capable of binding to PPARg and induces PPARg…”
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Identification and characterization of a novel Epstein-Barr Virus-encoded circular RNA from LMP-2 Gene by Tan, Ke-En, Ng, Wei Lun, Marinov, Georgi K., Yu, Ken Hung-On, Tan, Lu Ping, Liau, Ee Shan, Goh, Sook Yan, Yeo, Kok Siong, Yip, Kevin Y., Lo, Kwok-Wai, Khoo, Alan Soo-Beng, Yap, Lee-Fah, Ea, Chee-Kwee, Lim, Yat-Yuen

“…Epstein-Barr virus (EBV) has been recently found to generate novel circular RNAs (circRNAs) through backsplicing. However, comprehensive catalogs of EBV…”
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Nasopharyngeal carcinoma in adolescent patients: A case series by Sathasivam, Hans Prakash, Chew, Selina Yuet Ling, Kim, Wee‐Ric, Saw, Chee‐Lynn, Tan, Lu Ping, Tengku Din, Tengku Ahmad Damitri Al‐Astani, Adam, Nurul‐Ashikin, Hasbullah, Harissa Husainy, Wan Sohaimi, Wan Fatihah, Tan, Tee‐Yong, Lum, Chee‐Lun, Pua, Kin‐Choo, Khoo, Alan Soo‐Beng

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Dielectrophoresis-based microfluidic platforms for cancer diagnostics by Chan, Jun Yuan, Ahmad Kayani, Aminuddin Bin, Md Ali, Mohd Anuar, Kok, Chee Kuang, Majlis, Burhanuddin Yeop, Hoe, Susan Ling Ling, Marzuki, Marini, Khoo, Alan Soo-Beng, Ostrikov, Kostya (Ken), Rahman, Md. Ataur, Sriram, Sharath

“…The recent advancement of dielectrophoresis (DEP)-enabled microfluidic platforms is opening new opportunities for potential use in cancer disease diagnostics…”
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Selective anticancer copper(II)-mixed ligand complexes: targeting of ROS and proteasomes by Ng, Chew Hee, Kong, Siew Ming, Tiong, Yee Lian, Maah, Mohd Jamil, Sukram, Nurhazwani, Ahmad, Munirah, Khoo, Alan Soo Beng

“…Copper compounds can be alternatives to platinum-based anticancer drugs. This study investigated the effects of a series of ternary copper(II) complexes,…”
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Ternary copper(II) complex: NCI60 screening, toxicity studies, and evaluation of efficacy in xenograft models of nasopharyngeal carcinoma by Ahmad, Munirah, Suhaimi, Shazlan-Noor, Chu, Tai-Lin, Abdul Aziz, Norazlin, Mohd Kornain, Noor-Kaslina, Samiulla, D S, Lo, Kwok-Wai, Ng, Chew-Hee, Khoo, Alan Soo-Beng

“…Copper(II) ternary complex, [Cu(phen)(C-dmg)(H2O)]NO3 was evaluated against a panel of cell lines, tested for in vivo efficacy in nasopharyngeal carcinoma…”
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Dielectrophoretic deformation of breast cancer cells for lab on a chip applications by Chan, Jun Yuan, Ahmad Kayani, Aminuddin Bin, Md Ali, Mohd Anuar, Kok, Chee Kuang, Ramdzan Buyong, Muhamad, Hoe, Susan Ling Ling, Marzuki, Marini, Soo‐Beng Khoo, Alan, Sriram, Sharath, Ostrikov, Kostya (Ken)

“…This paper presents the development and experimental analysis of a curved microelectrode platform for the DEP deformation of breast cancer cells (MDA‐MB‐231)…”
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Targeting the crosstalk of epigenetic modifications and immune evasion in nasopharyngeal cancer by Looi, Chin-King, Foong, Lian-Chee, Chung, Felicia Fei-Lei, Khoo, Alan Soo-Beng, Loo, Ee-Mun, Leong, Chee-Onn, Mai, Chun-Wai

“…Nasopharyngeal carcinoma (NPC) is a distinct type of head and neck cancer that is highly associated with Epstein-Barr virus (EBV) infection. EBV acts as an…”
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The use of neutrophil lymphocyte ratio to predict complications post cardiac surgery by Weedle, Rebecca C, Da Costa, Mark, Veerasingam, Devendran, Soo, Alan W S

“…Cardiac surgery remains the gold standard treatment for select cohorts of patients with coronary artery and valvular heart diseases. It induces an acute…”
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A Cell Internalizing Antibody Targeting Capsid Protein (p24) Inhibits the Replication of HIV-1 in T Cells Lines and PBMCs: A Proof of Concept Study by Ali, Syed A, Teow, Sin-Yeang, Omar, Tasyriq Che, Khoo, Alan Soo-Beng, Choon, Tan Soo, Yusoff, Narazah Mohd

“…There remains a need for newer therapeutic approaches to combat HIV/AIDS. Viral capsid protein p24 plays important roles in HIV pathogenesis. Peptides and…”
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Development of a luciferase/luciferin cell proliferation (XenoLuc) assay for real-time measurements of Gfp-Luc2-modified cells in a co-culture system by Teow, Sin-Yeang, Liew, Kitson, Che Mat, Mohd Firdaus, Marzuki, Marini, Abdul Aziz, Norazlin, Chu, Tai-Lin, Ahmad, Munirah, Khoo, Alan Soo-Beng

“…In vitro modelling of cancer cells is becoming more complex due to prevailing evidence of intimate interactions between cancer cells and their surrounding…”
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