Search Results - "Sonzogni, Silvina V"

Intergenerational transmission of maternal care deficiency and offspring development delay induced by perinatal protein malnutrition by Gianatiempo, Octavio, Sonzogni, Silvina V., Fesser, Estefanía A., Belluscio, Laura M., Smucler, Ezequiel, Sued, Mariela R., Cánepa, Eduardo T.

“…Objectives: Early life represents a sensitive and critical period for an individual. Nutrition plays a crucial role in the maturation and functional…”
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E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation by Carcagno, Abel L, Marazita, Mariela C, Ogara, María F, Ceruti, Julieta M, Sonzogni, Silvina V, Scassa, María E, Giono, Luciana E, Cánepa, Eduardo T

“…A central aspect of development and disease is the control of cell proliferation through regulation of the mitotic cycle. Cell cycle progression and…”
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Chromatin relaxation-mediated induction of p19INK4d increases the ability of cells to repair damaged DNA by Ogara, María F, Sirkin, Pablo F, Carcagno, Abel L, Marazita, Mariela C, Sonzogni, Silvina V, Ceruti, Julieta M, Cánepa, Eduardo T

“…The maintenance of genomic integrity is of main importance to the survival and health of organisms which are continuously exposed to genotoxic stress. Cells…”
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CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response by Marazita, Mariela C, Ogara, M Florencia, Sonzogni, Silvina V, Martí, Marcelo, Dusetti, Nelson J, Pignataro, Omar P, Cánepa, Eduardo T

“…DNA damage triggers a phosphorylation-based signaling cascade known as the DNA damage response. p19INK4d, a member of the INK4 family of CDK4/6 inhibitors, has…”
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Oxidative stress associated with spatial memory impairment and social olfactory deterioration in female mice reveals premature aging aroused by perinatal protein malnutrition by Ferroni, Nadina M., Chertoff, Mariela J., Alberca, Carolina D., Berardino, Bruno G., Gianatiempo, Octavio, Brahamian, Martin, Levi, Valeria, Urrutia, Leandro, Falasco, Germán, Cánepa, Eduardo T., Sonzogni, Silvina V.

“…Early-life adversity, like perinatal protein malnutrition, increases the vulnerability to develop long-term alterations in brain structures and function. This…”
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Impaired social cognition caused by perinatal protein malnutrition evokes neurodevelopmental disorder symptoms and is intergenerationally transmitted by Fesser, Estefanía A., Gianatiempo, Octavio, Berardino, Bruno G., Alberca, Carolina D., Urrutia, Leandro, Falasco, Germán, Sonzogni, Silvina V., Chertoff, Mariela, Cánepa, Eduardo T.

“…Nutritional inadequacy before birth and during postnatal life can seriously interfere with brain development and lead to persistent deficits in learning and…”
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Limited contextual memory and transcriptional dysregulation in the medial prefrontal cortex of mice exposed to early protein malnutrition are intergenerationally transmitted by Fesser, Estefanía A., Gianatiempo, Octavio, Berardino, Bruno G., Ferroni, Nadina M., Cambiasso, Maite, Fontana, Vanina A., Calvo, Juan C., Sonzogni, Silvina V., Cánepa, Eduardo T.

“…Memory contextualization is vital for the subsequent retrieval of relevant memories in specific situations and is a critical dimension of social cognition. The…”
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Perinatal protein malnutrition induces the emergence of enduring effects and age-related impairment behaviors, increasing the death risk in a mouse model by Ferroni, Nadina M., Berardino, Bruno G., Belluscio, Laura M., Fernández, María S., Fesser, Estefanía A., Sonzogni, Silvina V., Cánepa, Eduardo T.

“…Early-life adversity impacts on the offspring's brain development and is associated with a higher risk of developing age-associated diseases. In particular,…”
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CDK5-mediated phosphorylation of p19INK4d avoids DNA damage-induced neurodegeneration in mouse hippocampus and prevents loss of cognitive functions by Ogara, María Florencia, Belluscio, Laura M., de la Fuente, Verónica, Berardino, Bruno G., Sonzogni, Silvina V., Byk, Laura, Marazita, Mariela, Cánepa, Eduardo T.

“…DNA damage, which perturbs genomic stability, has been linked to cognitive decline in the aging human brain, and mutations in DNA repair genes have…”
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p19INK4d is involved in the cellular senescence mechanism contributing to heterochromatin formation by Sonzogni, Silvina V., Ogara, María Florencia, Belluscio, Laura M., Castillo, Daniela S., Scassa, María E., Cánepa, Eduardo T.

“…During evolution, organisms with renewable tissues have developed mechanisms to prevent tumorigenesis, including cellular senescence and apoptosis. Cellular…”
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Nuclear translocation of p19INK4d in response to oxidative DNA damage promotes chromatin relaxation by Sonzogni, Silvina V., Ogara, María F., Castillo, Daniela S., Sirkin, Pablo F., Radicella, J. Pablo, Cánepa, Eduardo T.

“…DNA is continuously exposed to damaging agents that can lead to changes in the genetic information with adverse consequences. Nonetheless, eukaryotic cells…”
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E2F1 transcription is induced by genotoxic stress through ATM/ATR activation by Carcagno, Abel L., Ogara, María F., Sonzogni, Silvina V., Marazita, Mariela C., Sirkin, Pablo F., Ceruti, Julieta M., Cánepa, Eduardo T.

“…E2F1, a member of the E2F family of transcription factors, plays a critical role in controlling both cell cycle progression and apoptotic cell death in…”
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Chromatin Relaxation-Mediated Induction of p19INK4d Increases the Ability of Cells to Repair Damaged DNA. e61143 by Ogara, Maria F, Sirkin, Pablo F, Carcagno, Abel L, Marazita, Mariela C, Sonzogni, Silvina V, Ceruti, Julieta M, Canepa, Eduardo T

“…The maintenance of genomic integrity is of main importance to the survival and health of organisms which are continuously exposed to genotoxic stress. Cells…”
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