Search Results - "Sonoda, Yudai"
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Chemical augmentation of mitochondrial electron transport chains tunes T cell activation threshold in tumors
Published in Journal for immunotherapy of cancer (01-02-2022)“…BackgroundCancer immunotherapy shows insufficient efficacy for low immunogenic tumors. Furthermore, tumors often downregulate antigen and major…”
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Journal Article -
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CCR8-targeted specific depletion of clonally expanded Treg cells in tumor tissues evokes potent tumor immunity with long-lasting memory
Published in Proceedings of the National Academy of Sciences - PNAS (15-02-2022)“…Foxp3-expressing CD25 CD4 regulatory T cells (Tregs) are abundant in tumor tissues. Here, hypothesizing that tumor Tregs would clonally expand after they are…”
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Journal Article