Search Results - "Sonobe, Yukiko"
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Neutrophil-to-lymphocyte ratio is a prognostic factor reflecting immune condition of tumor microenvironment in squamous cell lung cancer
Published in Scientific reports (03-01-2024)“…Inflammatory factors in the peripheral blood, such as the C-reactive protein level and neutrophil-to-lymphocyte ratio (NLR), are prognostic markers in multiple…”
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MITF suppression improves the sensitivity of melanoma cells to a BRAF inhibitor
Published in Cancer letters (28-11-2017)“…Microphthalmia-associated transcription factor (MITF) is expressed in melanomas and has a critical role in melanocyte development and transformation. Because…”
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An anti-glypican 3/CD3 bispecific T cell-redirecting antibody for treatment of solid tumors
Published in Science translational medicine (04-10-2017)“…Cancer care is being revolutionized by immunotherapies such as immune checkpoint inhibitors, engineered T cell transfer, and cell vaccines. The bispecific T…”
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MITF suppression by CH5552074 inhibits cell growth in melanoma cells
Published in Cancer chemotherapy and pharmacology (01-06-2017)“…Purpose Although treatment of melanoma with BRAF inhibitors and immune checkpoint inhibitors achieves a high response rate, a subset of melanoma patients with…”
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Molecular subtypes of lung adenocarcinoma present distinct immune tumor microenvironments
Published in Cancer science (01-06-2024)“…Overcoming resistance to immune checkpoint inhibitors is an important issue in patients with non‐small‐cell lung cancer (NSCLC). Transcriptome analysis shows…”
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Tumor-infiltrating Leukocyte Profiling Defines Three Immune Subtypes of NSCLC with Distinct Signaling Pathways and Genetic Alterations
Published in Cancer research communications (01-06-2023)“…Resistance to immune checkpoint blockade remains challenging in patients with non-small cell lung cancer (NSCLC). Tumor-infiltrating leukocyte (TIL) quantity,…”
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