Search Results - "Sonnenberg, E"

Quantitative Trait Loci on Chromosomes 3 and 17 Influence Phenotypes of the Metabolic Syndrome by Kissebah, A H, Sonnenberg, G E, Myklebust, J, Goldstein, M, Broman, K, James, R G, Marks, J A, Krakower, G R, Jacob, H J, Weber, J, Martin, L, Blangero, J, Comuzzie, A G

“…Recent research has emphasized the importance of the metabolic cluster, which includes glucose intolerance, dyslipidemia, and high blood pressure, as a strong…”
Get full text

novel pathway to the manifestations of metabolic syndrome by Sonnenberg, G.E, Krakower, G.R, Kissebah, A.H

“…Pathways leading from obesity to the manifestations of metabolic syndrome involve a number of metabolic risk factors, as well as adipokines, mediators of…”
Get full text

A Phase 1 first‐in‐human study of the safety, tolerability, and pharmacokinetics of the ROBO2 fusion protein PF‐06730512 in healthy participants by Lim, Chay Ngee, Kantaridis, Constantino, Huyghe, Isabelle, Gorman, Donal, Berasi, Stephen, Sonnenberg, Gabriele E.

“…Proteinuria associated with podocyte effacement is a hallmark of focal segmental glomerulosclerosis (FSGS). Preclinical studies implicated ROBO2/SLIT2…”
Get full text

Expression and distribution of the transient receptor potential cationic channel ankyrin 1 (TRPA1) in the human vagina by Ückert, S, Sonnenberg, J E, Albrecht, K, Kuczyk, M A, Hedlund, P

“…The transient receptor potential cationic channel type A1 (TRPA1), belonging to a superfamily of cationic membrane channels, has been suggested to act as…”
Get full text

Exposure of Human Seminal Vesicle Tissue to Phosphodiesterase (PDE) Inhibitors Antagonizes the Contraction Induced by Norepinephrine and Increases Production of Cyclic Nucleotides by Birowo, Ponco, Ückert, Stefan, Kedia, George T, Sonnenberg, Joachim E, Sandner, Peter, Thon, Walter F, Scheller, Friedemann, Rahardjo, Djoko, Kuczyk, Markus A

“…Objectives To investigate further the role of phosphodiesterase (PDE) isoenzymes in the control of human seminal vesicle (SV) smooth muscle contractility, we…”
Get full text

Genetic Linkage and Association of the Growth Hormone Secretagogue Receptor (Ghrelin Receptor) Gene in Human Obesity by BAESSLER, Andrea, HASINOFF, Michael J, COMUZZIE, Anthony G, KISSEBAH, Ahmed H, KWITEK, Anne E, FISCHER, Marcus, REINHARD, Wibke, SONNENBERG, Gabriele E, OLIVIER, Michael, ERDMANN, Jeanette, SCHUNKERT, Heribert, DOERING, Angela, JACOB, Howard J

“…Genetic Linkage and Association of the Growth Hormone Secretagogue Receptor (Ghrelin Receptor) Gene in Human Obesity Andrea Baessler 1 2 , Michael J. Hasinoff…”
Get full text

Characterization of the Effects of Various Drugs Likely to Affect Smooth Muscle Tension on Isolated Human Seminal Vesicle Tissue by Birowo, Ponco, Ückert, Stefan, Kedia, George T, Sonnenberg, Joachim E, Thon, Walter F, Rahardjo, Djoko, Kuczyk, Markus A

“…Objectives To investigate the effects of different classes of drugs on the isometric tension of isolated human seminal vesicle (SV) tissue. The contractility…”
Get full text

Placental Failure in Mice Lacking the Mammalian Homolog of Glial Cells Missing, GCMa by Schreiber, Jörg, Riethmacher-Sonnenberg, Eva, Riethmacher, Dieter, Tuerk, Elisabeth E., Enderich, Janna, Bösl, Michael R., Wegner, Michael

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Scatter Factor/Hepatocyte Growth Factor and Its Receptor, the c-Met Tyrosine Kinase, Can Mediate a Signal Exchange between Mesenchyme and Epithelia during Mouse Development by Sonnenberg, Eva, Meyer, Dirk, Weidner, K. Michael, Birchmeier, Carmen

“…Scatter factor/hepatocyte growth factor (SF/HGF) has potent motogenic, mitogenic, and morphogenetic activities on epithelial cells in vitro. The cell surface…”
Get full text

Gallstones: Genetics versus environment by NAKEEB, Attila, COMUZZIE, Anthony G, MARTIN, Lisa, SONNENBERG, Gabriele E, SWARTZ-BASILE, Debra, KISSEBAH, Ahmed H, PITT, Henry A

“…The aim of this study was to determine if a significant genetic component contributes to the pathogenesis of symptomatic gallstones. Gallstones represent a…”
Get full text

The Effect of Colorectal Cancer (CRC) Control Programs on Access to Care for Colorectal Surgery Patients by Bansal, N, Sonnenberg, E, Meise, C.K, Reinke, C.E, Karakousis, G.C, Bartlett, E.K, Mahmoud, N.N, Roses, R.E, Kelz, R.R

Get full text

Major Quantitative Trait Locus for Resting Heart Rate Maps to a Region on Chromosome 4 by Martin, Lisa J, Comuzzie, Anthony G, Sonnenberg, Gabriele E, Myklebust, Joel, James, Roland, Marks, Jacqueline, Blangero, John, Kissebah, Ahmed H

“…ABSTRACT—Multiple studies have identified resting heart rate as a risk factor for cardiovascular disease independent of other cardiovascular disease risk…”
Get full text

Pharmacokinetics and pharmacodynamics of PF‐05190457: The first oral ghrelin receptor inverse agonist to be profiled in healthy subjects by Denney, William S., Sonnenberg, Gabriele E., Carvajal‐Gonzalez, Santos, Tuthill, Theresa, Jackson, V. Margaret

“…Aim To evaluate safety, tolerability and pharmacokinetics of oral PF‐05190457, an oral ghrelin receptor inverse agonist, in healthy adults. Methods Single…”
Get full text

Effects of endopeptidase inhibition on the relaxation response of isolated human penile erectile tissue to vasoactive peptides by Rahardjo, H. E., Reichelt, K., Sonnenberg, J. E., Sohn, M., Kuczyk, M. A., Ückert, S.

“…Summary Peptides, such as CNP, CGRP and VIP, are involved in the function of male penile erectile tissue. Tissue levels of said peptides are controlled by the…”
Get full text

Leptin : A significant indicator of total body fat but not of visceral fat and insulin insensitivity in African-American women by DUA, A, HENNES, M. I, HOFFMANN, R. G, MAAS, D. L, KRAKOWER, G. R, SONNENBERG, G. E, KISSEBAH, A. H

“…The recently cloned adipose tissue hormone leptin has been proposed to be involved in the neuroendocrine regulation of adiposity and its metabolic sequelae…”
Get full text

Genetic determinants of obesity-related lipid traits by Sonnenberg, Gabriele E., Krakower, Glenn R., Martin, Lisa J., Olivier, Michael, Kwitek, Anne E., Comuzzie, Anthony G., Blangero, John, Kissebah, Ahmed H.

“…In our ongoing effort to identify genes influencing the biological pathways that underlie the metabolic disturbances associated with obesity, we performed…”
Get full text

Decreasing the Rate of Metabolic Ketone Reduction in the Discovery of a Clinical Acetyl-CoA Carboxylase Inhibitor for the Treatment of Diabetes by Griffith, David A, Kung, Daniel W, Esler, William P, Amor, Paul A, Bagley, Scott W, Beysen, Carine, Carvajal-Gonzalez, Santos, Doran, Shawn D, Limberakis, Chris, Mathiowetz, Alan M, McPherson, Kirk, Price, David A, Ravussin, Eric, Sonnenberg, Gabriele E, Southers, James A, Sweet, Laurel J, Turner, Scott M, Vajdos, Felix F

“…Acetyl-CoA carboxylase (ACC) inhibitors offer significant potential for the treatment of type 2 diabetes mellitus (T2DM), hepatic steatosis, and cancer…”
Get full text

Imaging of gastrointestinal stromal tumors before and after imatinib mesylate therapy by Shankar, S, Dundamadappa, S K, Karam, A R, Stay, R M, van Sonnenberg, E

“…Gastrointestinal stromal tumors (GISTs) account for the majority of gastrointestinal mesenchymal tumors. Recent advances in treatment using the molecular…”
Get more information

Plasma leptin and insulin levels in weight-reduced obese women with normal body mass index: relationships with body composition and insulin by GUVEN, S, EL-BERSHAWI, A, SONNENBERG, G. E, WILSON, C. R, HOMNANN, R. G, KRAKOWER, G. R, KISSEBAH, A. H

“…Plasma leptin and insulin levels in weight-reduced obese women with normal body mass index: relationships with body composition and insulin. S Guven , A…”
Get full text

Leptin: a significant indicator of total body fat but not of visceral fat and insulin insensitivity in African-American women by Dua, A., Hennes, M. I., Hoffmann, R. G., Maas, D. L., Krakower, G. R., Sonnenberg, G. E., Kissebah, A. H.

“…Leptin: a significant indicator of total body fat but not of visceral fat and insulin insensitivity in African-American women. A Dua , M I Hennes , R G…”
Get full text