Search Results - "Sonne, Nina"

Mono and dual agonists of the amylin, calcitonin, and CGRP receptors and their potential in metabolic diseases by Sonne, Nina, Karsdal, Morten A., Henriksen, Kim

“…Therapies for metabolic diseases are numerous, yet improving insulin sensitivity beyond that induced by weight loss remains challenging. Therefore, search…”
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Dual amylin and calcitonin receptor agonist treatment improves insulin sensitivity and increases muscle-specific glucose uptake independent of weight loss by Larsen, Anna Thorsø, Melander, Simone A., Sonne, Nina, Bredtoft, Emma, Al-Rubai, Mays, Karsdal, Morten A., Henriksen, Kim

“…Dual amylin and calcitonin receptor agonists (DACRAs) are known to induce significant weight loss as well as improve glucose tolerance, glucose control, and…”
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The dual amylin and calcitonin receptor agonist KBP-089 and the GLP-1 receptor agonist liraglutide act complimentarily on body weight reduction and metabolic profile by Larsen, Anna Thorsø, Gydesen, Sofie, Sonne, Nina, Karsdal, Morten Asser, Henriksen, Kim

“…Weight loss therapy is becoming more and more important, and two classes of molecules, namely amylin receptor and GLP-1 receptor agonists, have shown promise…”
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The Impact of Exposure Profile on the Efficacy of Dual Amylin and Calcitonin Receptor Agonist Therapy by Sonne, Nina, Larsen, Anna Thorsø, Karsdal, Morten Asser, Henriksen, Kim

“…Background: Dual Amylin and Calcitonin Receptor Agonists (DACRAs) are treatment candidates for obesity and type 2 diabetes. Recently, a once-weekly DACRA…”
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The calcitonin receptor plays a major role in glucose regulation as a function of dual amylin and calcitonin receptor agonist therapy by Larsen, Anna Thorsø, Sonne, Nina, Andreassen, Kim Vietz, Karsdal, Morten Asser, Henriksen, Kim

“…Amylin treatment improves body weight and glucose control, though limited by a short action and need for high doses. DACRAs are dual amylin and calcitonin…”
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The Dual Amylin and Calcitonin Receptor Agonist KBP-088 Induces Weight Loss and Improves Insulin Sensitivity Superior to Chronic Amylin Therapy by Larsen, Anna Thorsø, Sonne, Nina, Andreassen, Kim Vietz, Gehring, Kristoffer, Karsdal, Morten Asser, Henriksen, Kim

“…KBP-088 (KeyBiosciencePeptide 088) is a potent dual amylin and calcitonin receptor agonist (DACRA). DACRAs are known to elicit potent activity in terms of…”
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The Dual Amylin and Calcitonin Receptor Agonist, KBP-066, Induces an Equally Potent Weight Loss Across a Broad Dose Range While Higher Doses May Further Improve Insulin Action by Sonne, Nina, Larsen, Anna Thorsø, Andreassen, Kim Vietz, Karsdal, Morten Asser, Henriksen, Kim

“…Pharmacological treatment with dual amylin and calcitonin receptor agonists (DACRAs) cause significant weight loss and improvement of glucose homeostasis. In…”
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Early laparoscopic cholecystectomy for acute cholecystitis is safe regardless of timing by Bundgaard, Nina Sonne, Bohm, Aske, Hansted, Anna Koldbro, Skovsen, Anders Peter

“…Purpose The optimal timing for laparoscopic cholecystectomy for acute cholecystitis (AC) has not been resolved. In the revised Tokyo Guidelines from 2018…”
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824-P: Dual Amylin and Calcitonin Receptor Agonists Improve Insulin Sensitivity and Increase Tissue-Specific Glucose Uptake Independent of Weight Loss by LARSEN, ANNA T., SONNE, NINA, BREDTOFT, EMMA-MARIE, KARSDAL, MORTEN A., HENRIKSEN, KIM

“…Dual amylin and calcitonin receptor agonists (DACRAs) are known to induce a significant weight loss and improve glucose tolerance and glucose control in rats…”
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A novel dual amylin and calcitonin receptor agonist, KBP‐089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference by Gydesen, Sofie, Hjuler, Sara Toftegaard, Freving, Zenia, Andreassen, Kim Vietz, Sonne, Nina, Hellgren, Lars I, Karsdal, Morten Asser, Henriksen, Kim

“…Background and Purpose Obesity and associated co‐morbidities, such as type 2 diabetes and non‐alcoholic fatty liver disease, are major health challenges…”
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823-P: The Long-Acting Dual Amylin and Calcitonin Receptor Agonist KBP Has Increased Efficacy on Weight Loss and Glucose Control Compared with Cagrilintide in Obese and Diabetic Rats by LARSEN, ANNA T., SONNE, NINA, MOHAMED, KHALED ELHADY, BREDTOFT, EMMA-MARIE, ANDERSEN, FREDERIK, KARSDAL, MORTEN A., HENRIKSEN, KIM

“…Long-acting dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates for treatment of type 2 diabetes (T2D) and obesity due to their…”
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1993-P: Deconstruction of the Role of the Amylin and Calcitonin Receptors in the Regulation of Body Weight and Glucose Tolerance by LARSEN, ANNA T., SONNE, NINA, ANDREASSEN, KIM V., KARSDAL, MORTEN ASSER, HENRIKSEN, KIM

“…Dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates for treatment of T2D and obesity due to their beneficial effects on body weight,…”
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Dose Frequency Optimization of the Dual Amylin and Calcitonin Receptor Agonist KBP-088: Long-Lasting Improvement in Food Preference and Body Weight Loss by Larsen, Anna Thorsø, Sonne, Nina, Andreassen, Kim V, Karsdal, Morten A, Henriksen, Kim

“…Dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates for treatment of type 2 diabetes and obesity because of their beneficial effects on…”
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2016-P: High Dose DACRA Treatment Improves Glucose Homeostasis, without Additional Weight Loss by SONNE, NINA, LARSEN, ANNA T., ANDREASSEN, KIM V., KARSDAL, MORTEN ASSER, HENRIKSEN, KIM

“…KBP is a Dual Amylin and Calcitonin Receptor Agonist (DACRA). DACRAs have shown efficacy on weight loss and glucose control in rats. However, it is unclear…”
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1995-P: Optimization of DACRA Dosing Frequency—The Balance between Efficacy and Tolerability by LARSEN, ANNA T., ANDREASSEN, KIM V., SONNE, NINA, KARSDAL, MORTEN ASSER, HENRIKSEN, KIM

“…Potent dual amylin and calcitonin receptor agonists (DACRAs) are novel candidates for treatment of T2D and obesity due to their beneficial effects on body…”
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Treatment of anal fissures by Bundgaard, Nina Sonne, Hagen, Kikke Kirsten, Nordholm-Carstensen, Andreas

“…Anal fissure is a common ailment, however, the pathophysiology and optimal treatment strategy is unclear. Anal fissures may be classified as acute or chronic…”
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