Search Results - "Sonn, Seong‐Keun"

The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke by Kim, Sinai, Lee, Wonhyo, Jo, Huiju, Sonn, Seong-Keun, Jeong, Se-Jin, Seo, Seungwoon, Suh, Joowon, Jin, Jing, Kweon, Hyae Yon, Kim, Tae Kyeong, Moon, Shin Hye, Jeon, Sejin, Kim, Jong Woo, Kim, Yu Ri, Lee, Eun-Woo, Shin, Hwa Kyoung, Park, Sung Ho, Oh, Goo Taeg

“…Ischemic stroke is the leading cause of immortal disability and death worldwide. For treatment in the acute phase, it is necessary to control excessive…”
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Anti-Inflammatory Actions of Soluble Ninjurin-1 Ameliorate Atherosclerosis by Jeon, Sejin, Kim, Tae Kyeong, Jeong, Se-Jin, Jung, In-Hyuk, Kim, Nayoung, Lee, Mi-Ni, Sonn, Seong-Keun, Seo, Seungwoon, Jin, Jing, Kweon, Hyae Yon, Kim, Sinai, Shim, Dahee, Park, Young Mi, Lee, Sang-Hak, Kim, Kyu-Won, Cybulsky, Myron I., Shim, Hyunbo, Roh, Tae-Young, Park, Woong-Yang, Lee, Hae-Ock, Choi, Jae-Hoon, Park, Sung Ho, Oh, Goo Taeg

“…BACKGROUND:Macrophages produce many inflammation-associated molecules, released by matrix metalloproteinases, such as adhesion molecules, and cytokines, as…”
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2′–5′ oligoadenylate synthetase‑like 1 (OASL1) protects against atherosclerosis by maintaining endothelial nitric oxide synthase mRNA stability by Kim, Tae Kyeong, Jeon, Sejin, Park, Seonjun, Sonn, Seong-Keun, Seo, Seungwoon, Suh, Joowon, Jin, Jing, Kweon, Hyae Yon, Kim, Sinai, Moon, Shin Hye, Kweon, Okhee, Koo, Bon-Hyeock, Kim, Nayoung, Lee, Hae-Ock, Kim, Young-Myeong, Kim, Young-Joon, Park, Sung Ho, Oh, Goo Taeg

“…Endothelial nitric oxide synthase (eNOS) decreases following inflammatory stimulation. As a master regulator of endothelial homeostasis, maintaining optimal…”
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Pancreatic β-cell mitophagy as an adaptive response to metabolic stress and the underlying mechanism that involves lysosomal Ca2+ release by Oh, Soo-Jin, Park, Kihyoun, Sonn, Seong Keun, Oh, Goo Taeg, Lee, Myung-Shik

“…Mitophagy is an excellent example of selective autophagy that eliminates damaged or dysfunctional mitochondria, and it is crucial for the maintenance of…”
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Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway by Kweon, Hyae Yon, Lee, Mi-Ni, Dorfel, Max, Seo, Seungwoon, Gottlieb, Leah, PaPazyan, Thomas, McTiernan, Nina, Ree, Rasmus, Bolton, David, Garcia, Andrew, Flory, Michael, Crain, Jonathan, Sebold, Alison, Lyons, Scott, Ismail, Ahmed, Marchi, Elaine, Sonn, Seong-keun, Jeong, Se-Jin, Jeon, Sejin, Ju, Shinyeong, Conway, Simon J, Kim, Taesoo, Kim, Hyun-Seok, Lee, Cheolju, Roh, Tae-Young, Arnesen, Thomas, Marmorstein, Ronen, Oh, Goo Taeg, Lyon, Gholson J

“…Amino-terminal acetylation is catalyzed by a set of N-terminal acetyltransferases (NATs). The NatA complex (including X-linked Naa10 and Naa15) is the major…”
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CD137‐inducing factors from T cells and macrophages accelerate the destabilization of atherosclerotic plaques in hyperlipidemic mice by Jung, In‐Hyuk, Choi, Jae‐Hoon, Jin, Jing, Jeong, Se‐Jin, Jeon, Sejin, Lim, Chaeji, Lee, Mi‐Ran, Yoo, Ji‐Young, Sonn, Seong‐Keun, Kim, Young Ho, Choi, Beom Kyu, Kwon, Byoung S., Seoh, Ju‐Young, Lee, Cheol Whan, Kim, Dae‐Yong, Oh, Goo Taeg

“…CD137 (4‐1BB), a member of the tumor necrosis factor receptor superfamily, has been reported to be expressed in atherosclerotic plaques, and to promote lesion…”
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ER-associated CTRP1 regulates mitochondrial fission via interaction with DRP1 by Sonn, Seong Keun, Seo, Seungwoon, Yang, Jaemoon, Oh, Ki Sook, Chen, Hsiuchen, Chan, David C., Rhee, Kunsoo, Lee, Kyung S., Yang, Young, Oh, Goo Taeg

“…C1q/TNF-related protein 1 (CTRP1) is a CTRP family member that has collagenous and globular C1q-like domains. The secreted form of CTRP1 is known to be…”
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Peroxiredoxin 3 deficiency induces cardiac hypertrophy and dysfunction by impaired mitochondrial quality control by Sonn, Seong Keun, Song, Eun Ju, Seo, Seungwoon, Kim, Young Yeon, Um, Jee-Hyun, Yeo, Franklin Joonyeop, Lee, Da Seul, Jeon, Sejin, Lee, Mi-Ni, Jin, Jing, Kweon, Hyae Yon, Kim, Tae Kyeong, Kim, Sinai, Moon, Shin Hye, Rhee, Sue Goo, Chung, Jongkyeong, Yang, Jaemoon, Han, Jin, Choi, Eui-Young, Lee, Sung Bae, Yun, Jeanho, Oh, Goo Taeg

“…Mitochondrial quality control (MQC) consists of multiple processes: the prevention of mitochondrial oxidative damage, the elimination of damaged mitochondria…”
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Evaluation of VCAM-1 antibodies as therapeutic agent for atherosclerosis in apolipoprotein E-deficient mice by Park, Jong-Gil, Ryu, Su Yeon, Jung, In-Hyuk, Lee, You-Han, Kang, Kyung Jae, Lee, Mi-Ran, Lee, Mi-Ni, Sonn, Seong Keun, Lee, Jeong Hwa, Lee, Hang, Oh, Goo Taeg, Moon, Kyungduk, Shim, Hyunbo

“…Abstract Objective Blocking agents targeting cell adhesion molecules have been developed to prevent cardiovascular diseases such as atherosclerosis, whereas…”
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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs by Jin, Jing, Jung, In-Hyuk, Moon, Shin Hye, Jeon, Sejin, Jeong, Se-Jin, Sonn, Seong-Keun, Seo, Seungwoon, Lee, Mi-Ni, Song, Eun Ju, Kweon, Hyae Yon, Kim, Sinai, Kim, Tae Kyeong, Kim, Juyang, Cho, Hong Rae, Choi, Jae-Hoon, Kwon, Byungsuk, Oh, Goo Taeg

“…CD137, a potent costimulatory receptor for CD8+ T cells, is expressed in various non-T cells, but little is known about its regulatory functions in these…”
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Mitochondrial H2O2 Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury by Kim, Sin Ri, Park, Ji Won, Choi, You-Jin, Sonn, Seong Keun, Oh, Goo Taeg, Lee, Byung-Hoon, Chang, Tong-Shin

“…Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences, including hepatic injury. The detrimental hepatotoxicity of…”
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5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion by Choi, Jae-Hoon, Park, Jong-Gil, Jeon, Hyung-Jun, Kim, Mi-Sun, Lee, Mi-Ran, Lee, Mi-Ni, Sonn, Seong-Keun, Kim, Jae-Hong, Lee, Mun-Han, Choi, Myung-Sook, Park, Yong-Bok, Kwon, Oh-Seung, Jeong, Tae-Sook, Lee, Woo-Song, Shim, Hyun-Bo, Shin, Dong-Hae, Oh, Goo-Taeg

“…A variety of benzylidenethiazole analogs have been demonstrated to inhibit 5-lipoxygenase (5-LOX). Here we report the anti-atherogenic potential of…”
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Anti-atherogenic effect of BHB-TZD having inhibitory activities on cyclooxygenase and 5-lipoxygenase in hyperlipidemic mice by Choi, Jae-Hoon, Jeon, Hyung Jun, Park, Jong-Gil, Sonn, Seong Keun, Lee, Mi-Ran, Lee, Mi-Ni, You, Hye Jin, Kim, Geun-Young, Kim, Jae-Hong, Lee, Mun Han, Kwon, Oh-Seung, Nam, Ki-Hoan, Kim, Hyoung-Chin, Jeong, Tae-Sook, Lee, Woo Song, Oh, Goo Taeg

“…Abstract Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX), which play pivotal roles in atherogenesis, have been reported to be involved in plaque stability…”
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Prdx3 deficiency aggravates abdominal aortic aneurysm by inducing vascular smooth muscle cell senescence by Oh, Gootaeg, Jung, Moajury, Shim, Hyunbo, Sonn, Seong Keun, Lee, Da Seul

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Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity by Seo, Seungwoon, Sonn, Seong Keun, Kweon, Hyae Yon, Jin, Jing, Kume, Tsutomu, Ko, Je Yeong, Park, Jong Hoon, Oh, Goo Taeg

“…Intraflagellar transport 46 (IFT46) is an integral subunit of the IFT-B complex, playing a key role in the assembly and maintenance of primary cilia…”
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Impaired TFEB activation and mitophagy as a cause of PPP3/calcineurin inhibitor-induced pancreatic β-cell dysfunction by Park, Kihyoun, Sonn, Seong Keun, Seo, Seungwoon, Kim, Jinyoung, Hur, Kyu Yeon, Oh, Goo Taeg, Lee, Myung-Shik

“…Macroautophagy/autophagy or mitophagy plays crucial roles in the maintenance of pancreatic β-cell function. PPP3/calcineurin can modulate the activity of TFEB,…”
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Extracellular peroxiredoxin 5 exacerbates atherosclerosis via the TLR4/MyD88 pathway by Kweon, Hyae Yon, Song, Eun Ju, Jeong, Se-Jin, Lee, SoonHo, Sonn, Seong-Keun, Seo, Seungwoon, Jin, Jing, Kim, Sinai, Kim, Tae Kyeong, Moon, Shin Hye, Kim, Doyeon, Park, Young Mi, Woo, Hyun Ae, Oh, Goo Taeg

“…Peroxiredoxin 5 (PRDX5), an atypical 2-Cys peroxiredoxin (PRDX), is known to regulate global oxidative stresses and inflammatory responses. Inflammation and…”
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Mitochondrial H 2 O 2 Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury by Kim, Sin Ri, Park, Ji Won, Choi, You-Jin, Sonn, Seong Keun, Oh, Goo Taeg, Lee, Byung-Hoon, Chang, Tong-Shin

“…Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences, including hepatic injury. The detrimental hepatotoxicity of…”
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Mitochondrial H[sub.2]O[sub.2] Is a Central Mediator of Diclofenac-Induced Hepatocellular Injury by Kim, Sin Ri, Park, Ji Won, Choi, You-Jin, Sonn, Seong Keun, Oh, Goo Taeg, Lee, Byung-Hoon, Chang, Tong-Shin

“…Nonsteroidal anti-inflammatory drug (NSAID) use is associated with adverse consequences, including hepatic injury. The detrimental hepatotoxicity of…”
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The adipokine Retnla modulates cholesterol homeostasis in hyperlipidemic mice by Lee, Mi-Ran, Lim, Chae-ji, Lee, You-Han, Park, Jong-Gil, Sonn, Seong Keun, Lee, Mi-Ni, Jung, In-Hyuk, Jeong, Se-Jin, Jeon, Sejin, Lee, Myoungsook, Oh, Ki Sook, Yang, Young, Kim, Jae Bum, Choi, Hueng-Sik, Jeong, Woojin, Jeong, Tae-Sook, Yoon, Won Kee, Kim, Hyoung Chin, Choi, Jae-Hoon, Oh, Goo Taeg

“…Hyperlipidemia is a well-recognized risk factor for atherosclerosis and can be regulated by adipokines. Expression of the adipokine resistin-like molecule…”
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