Search Results - "Sonmezler, Ozge"

The impact of rare and low-frequency genetic variants in common variable immunodeficiency (CVID) by Bisgin, Atil, Sonmezler, Ozge, Boga, Ibrahim, Yilmaz, Mustafa

“…Next Generation Sequencing (NGS) has uncovered hundreds of common and rare genetic variants involved in complex and rare diseases including immune deficiencies…”
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The emerging clinical relevance of genomic profiling in neuroendocrine tumours by Burak, Guney Isa, Ozge, Sonmezler, Cem, Mujde, Gulgun, Buyukdereli, Zeynep, Dogruca Yapar, Atil, Bisgin

“…Neuroendocrine tumours (NETs) arise from hormone-producing or nervous system cells and can develop from anywhere in the body. They have heterogeneous origins…”
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Germline landscape of BRCAs by 7-site collaborations as a BRCA consortium in Turkey by Bisgin, Atil, Sag, Sebnem Ozemri, Dogan, Muhammet E., Yildirim, Mahmut S., Gumus, Aydeniz Aydin, Akkus, Nejmiye, Balasar, Ozgur, Durmaz, Ceren D., Eroz, Recep, Altiner, Sule, Alemdar, Adem, Aliyeva, Lamia, Boga, Ibrahim, Cam, Fethi S., Dogan, Berkcan, Esbah, Onur, Hanta, Abdullah, Mujde, Cem, Ornek, Cemre, Ozer, Sinem, Rencuzogullari, Cagla, Sonmezler, Ozge, Bozdogan, Sevcan Tug, Dundar, Munis, Temel, Sehime G.

“…BRCA1/2 mutations play a significant role in cancer pathogenesis and predisposition particularly in breast, ovarian and prostate cancers. Thus, germline…”
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Abstract 4264: Liquid biopsy and FFPE tissue based somatic BRCA1/2 variant screening in breast and ovarian cancer by Boga, Ibrahim, Sonmezler, Ozge, Bisgin, Atil

“…Abstract Next generation sequencing (NGS) has widened its use since it provides highly precise and accurate genetic testing with reasonable costs in tumor…”
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Abstract 3602: Validation and implementation of next-generation sequencing in liquid biopsies by a novel NGS platform: Focus on non-small cell lung cancer by Bisgin, Atil, Sonmezler, Ozge, Boga, Ibrahim

“…Abstract Introduction: Liquid biopsy as a novel and non-invasive test for the surveillance of cancer is rapidly growing, by next-generation sequencing (NGS)…”
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Diagnostic utility of next generation sequencing for somatic variants in cancer: A seven year cumulative cohort by Boga, Ibrahim, Sonmezler, Ozge, Rencuzogullari, Cagla, Mujde, Cem, Tug Bozdogan, Sevcan, Bisgin, Atil

“…e15060 Background: Next generation sequencing (NGS) makes it possible to identify the specific molecular biomarkers to define patient eligibility for targeted…”
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Abstract 4154: The emerging clinical relevance of genomic profiling medicine in neuroendocrine tumors by Sonmezler, Ozge, Guney, Isa B., Mujde, Cem, Bisgin, Atil

“…Abstract Neuroendocrine tumors (NET) can develop everywhere in the body which have heterogeneous origins and complicated histology. Thus, genomic profiling…”
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Integration of Liquid Biopsies into Clinical Laboratory Applications via NGS in Cancer Diagnostics by Sonmezler, Ozge, Boga, Ibrahim, Bisgin, Atil

“…Next Generation Sequencing is one of the latest advances in molecular testing and clinical laboratory applications. Next Generation Sequencing techniques…”
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Abstract 1972: The significance of liquid biopsy in colorectal cancer via GeneReader NGS Systems by Mujde, Cem, Hanta, Abdullah, Sonmezler, Ozge, Rencuzogullari, Ahmet, Boga, Ibrahim, Bisgin, Atil

“…Abstract Background: In terms of precision medicine, not only tumoral tissue samples but also with liquid biopsy for somatic variants detection, have been used…”
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Meta-analysis and single-center experience on the comprehensive genomic characterization and landscape of BRCA1 and BRCA2 in Turkey by Bisgin, Atil, Boga, Ibrahim, Sonmezler, Ozge, Mujde, Cem, Hanta, Abdullah, Tug Bozdogan, Sevcan

“…Abstract only e13611 Background: The detection of BRCA1 and BRCA2 mutations both somatic and germ-line became essential for the clinical management strategies…”
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Clinical assessment of HRD scoring in relation to PARPi response in terms of statistical guidance on reporting results for CDx tests evaluation by Bisgin, Atil, Boga, Ibrahim, Eskut, Kaan Ihsan, Rencuzogullari, Cagla, Sonmezler, Ozge, Kose, Fatih, Besen, Ali Ayberk, Olmez, Omer Fatih, Disel, Umut, Kocer, Nazım Emrah, Bolat, Filiz, Jinga, Dan-Corneliu, Lazar, Ioana, Pathak, Surajit

“…e17597 Background: Homologous recombination deficiency (HRD) is a tumor characteristic that can be assessed via different biomarkers such as individual…”
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BRCA mutation characteristics in a series of index cases of breast cancer selected independent of family history by Bisgin, Atil, Boga, Ibrahim, Yalav, Orcun, Sonmezler, Ozge, Tug Bozdogan, Sevcan

“…Certain genetic predisposition factors, such as BRCA1 and BRCA2 mutations play a pivotal role in familial breast cancer development in both males and females…”
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Current Status of Genetic Diagnosis Laboratories and Frequency of Genetic Variants Associated with Cystic Fibrosis through a Newborn-Screening Program in Turkey by Bozdogan, Sevcan Tug, Mujde, Cem, Boga, Ibrahim, Sonmezler, Ozge, Hanta, Abdullah, Rencuzogullari, Cagla, Ozcan, Dilek, Altintas, Derya Ufuk, Bisgin, Atil

“…Cystic fibrosis (CF) is the most common worldwide, life-shortening multisystem hereditary disease, with an autosomal recessive inheritance pattern caused by…”
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Pre-operative Neo-adjuvant Chemotherapy Related miRNAs as Key Regulators and Therapeutic Targets in Colorectal Cancer by Yalav, Orcun, Sonmezler, Ozge, Erdogan, Kivilcim Eren, Rencuzogullari, Ahmet, Doran, Figen, Bisgin, Atil, Boga, Ibrahim

“…In colorectal cancer, the investigation of cancer pathogenesis and the determination of the relevant gene and gene pathways is particularly important to…”
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Site specific genetic differences in colorectal cancer via Next-Generation-Sequencing using a multigene panel by Rencuzogullari, Ahmet, Bisgin, Atil, Erdogan, Kivilcim Eren, Gumus, Serdar, Yalav, Orcun, Boga, Ibrahim, Sonmezler, Ozge, Eray, Ismail Cem

“…Next-generation sequencing (NGS) has been proposed as a comprehensive and efficient genomic profiling tool to guide personalized therapy for colorectal cancer…”
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AML-144 Investigating FLT3 Mutations In Acute Myeloid Leukemia: A Single-Center Real-World Data Study on Patient Outcomes and Treatment Strategies by Açar, İbrahim Halil, Dinçyürek, Hüseyin Derya, Sönmezler, Özge, Yıldız, Şule Menziletoğlu, Bişgin, Atıl, Güvenç, Birol

“…Acute myeloid leukemia (AML) is a complex hematological malignancy with considerable genetic heterogeneity. FMS-like tyrosine kinase 3 (FLT3) mutations are…”
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