Search Results - "Sonksen, Peter H"

The effects of recombinant human insulin‐like growth factor‐1/insulin‐like growth factor binding protein‐3 administration on lipid and carbohydrate metabolism in recreational athletes by Guha, Nishan, Nevitt, Simon P., Francis, Michael, Böhning, Walailuck, Böhning, Dankmar, Sönksen, Peter H., Holt, Richard I. G.

“…Objective Previous studies suggested that recombinant human IGF‐1 (rhIGF‐1) administration affects carbohydrate and lipid metabolism in healthy people and in…”
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Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse by Böhning, Dankmar, Böhning, Walailuck, Guha, Nishan, Cowan, David A, Sönksen, Peter H, Holt, Richard I G

“…The GH-2000 score has been developed as a powerful and unique technique for the detection of growth hormone misuse by sportsmen and women. The score depends…”
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The Effects of Growth Hormone and/or Testosterone in Healthy Elderly Men: A Randomized Controlled Trial by Giannoulis, Manthos G., Sonksen, Peter H., Umpleby, Margot, Breen, Louise, Pentecost, Claire, Whyte, Martin, McMillan, Carolyn V., Bradley, Clare, Martin, Finbarr C.

“…Context: Declines in GH and testosterone (Te) secretion may contribute to the detrimental aging changes of elderly men. Objective: To assess the effects of…”
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Erratum to: Statistical methodology for age-adjustment of the GH-2000 score detecting growth hormone misuse by Böhning, Dankmar, Böhning, Walailuck, Guha, Nishan, Cowan, David A, Sönksen, Peter H, Holt, Richard I G

“…After publication of the original article [1], it came to the authors' attention that there was an error affecting equation (7). A correction to this equation…”
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Novel markers to detect recombinant human insulin‐like growth factor‐I (rhIGF‐I)/rhIGF binding protein‐3 (rhIGFBP‐3) misuse in athletes by Holt, Richard I. G., Guha, Nishan, Böhning, Walailuck, Bartlett, Christiaan, Cowan, David A., Sönksen, Peter H., Böhning, Dankmar

“…Insulin‐like growth factor‐I (IGF‐I) is abused by elite athletes for its metabolic and anabolic effects. We have previously shown that it is possible to detect…”
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Insulin-like growth factor-I (IGF-I) misuse in athletes and potential methods for detection by Guha, Nishan, Cowan, David A., Sönksen, Peter H., Holt, Richard I. G.

“…To athletes, insulin-like growth factor-I (IGF-I) is an attractive performance-enhancing drug, particularly as an alternative to growth hormone (GH) because…”
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The development of decision limits for the GH-2000 detection methodology using additional insulin-like growth factor-I and amino-terminal pro-peptide of type III collagen assays by Holt, Richard I. G., Böhning, Walailuck, Guha, Nishan, Bartlett, Christiaan, Cowan, David A., Giraud, Sylvain, Bassett, E. Eryl, Sönksen, Peter H., Böhning, Dankmar

“…The GH‐2000 and GH‐2004 projects have developed a method for detecting GH misuse based on measuring insulin‐like growth factor‐I (IGF‐I) and the amino‐terminal…”
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Challenges in Detecting the Abuse of Growth Hormone in Sport by McHugh, Cathy M, Park, Roderick T, Sonksen, Peter H, Holt, Richard I.G

“…Growth hormone (GH) is reputed to be in widespread use in the sporting arena as a performance-enhancing agent and is on the list of banned substances published…”
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Influence of ethnicity on IGF-I and procollagen III peptide (P-III-P) in elite athletes and its effect on the ability to detect GH abuse by Erotokritou-Mulligan, Ioulietta, Bassett, E. Eryl, Cowan, David A., Bartlett, Christiaan, McHugh, Cathy, Sönksen, Peter H., Holt, Richard I. G.

“…Summary Context  A method based on the two GH dependent markers, IGF‐I and procollagen III peptide (P‐III‐P) has been proposed to detect exogenously…”
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The use of growth hormone (GH)-dependent markers in the detection of GH abuse in sport: Physiological intra-individual variation of IGF-I, type 3 pro-collagen (P-III-P) and the GH-2000 detection score by Erotokritou-Mulligan, Ioulietta, Eryl Bassett, E., Cowan, David A., Bartlett, Christiaan, Milward, Polly, Sartorio, Alessandro, Sönksen, Peter H., Holt, Richard I. G.

“…Summary Background  Growth Hormone is abused by athletes for its lipolytic and anabolic properties. Its use is prohibited by the World Anti‐Doping Agency. The…”
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The Effects of Growth Hormone and/or Testosterone on Whole Body Protein Kinetics and Skeletal Muscle Gene Expression in Healthy Elderly Men: A Randomized Controlled Trial by Giannoulis, Manthos G., Jackson, Nicola, Shojaee-Moradie, Fariba, Nair, K. Sreekumaran, Sonksen, Peter H., Martin, Finbarr C., Umpleby, A. Margot

“…Context: Alterations of protein turnover may contribute to the progressive decline of muscle mass with aging. Objective: Our objective was to examine the…”
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Biochemical markers of recombinant human insulin-like growth factor-I (rhIGF-I)/rhIGF binding protein-3 (rhIGFBP-3) misuse in athletes by Guha, Nishan, Erotokritou-Mulligan, Ioulietta, Nevitt, Simon P., Francis, Michael, Bartlett, Christiaan, Cowan, David A., Bassett, E. Eryl, Sönksen, Peter H., Holt, Richard I. G.

“…Insulin‐like growth factor‐I (IGF‐I) is reportedly misused by elite athletes, either alone or with growth hormone (GH). The GH‐2000 and GH‐2004 research groups…”
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The Growth Hormone/Insulin-Like Growth Factor-I Axis in Exercise and Sport by Gibney, James, Healy, Marie-Louise, Sönksen, Peter H

“…The syndrome of adult GH deficiency and the effects of GH replacement therapy provide a useful model with which to study the effects of the GH/IGF-I axis on…”
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The Effect of a Six-Month Exercise Program on Very Low-Density Lipoprotein Apolipoprotein B Secretion in Type 2 Diabetes by Alam, Saima, Stolinski, Michael, Pentecost, Claire, Boroujerdi, Massoud A., Jones, Richard H., Sonksen, Peter H., Umpleby, A. Margot

“…The dyslipidemia and insulin resistance of type 2 diabetes can be improved by aerobic exercise. The effect of 6 months supervised exercise on very low-density…”
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Hyperandrogenism controversy in elite women's sport: an examination and critique of recent evidence by Sőnksen, Peter H, Bavington, L Dawn, Boehning, Tan, Cowan, David, Guha, Nishan, Holt, Richard, Karkazis, Katrina, Ferguson-Smith, Malcolm Andrew, Mircetic, Jovan, Bőhning, Dankmar

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The use of growth hormone (GH)-dependent markers in the detection of GH abuse in sport: physiological intra-individual variation of IGF-I, type 3 pro-collagen (P-III-P) and the GH- 2000 detection score: authors' response by Erotokritou-Mulligan, Ioulietta, Eryl Bassett, E., Sönksen, Peter H., Holt, Richard I. G.

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Moving one step closer to catching the GH cheats: The GH-2004 experience by Holt, Richard I.G, Bassett, E. Eryl, Erotokritou-Mulligan, Ioulietta, McHugh, Cathy, Cowan, David, Bartlett, Christiaan, Sönksen, Peter H

“…Abstract Growth hormone is abused by athletes for its anabolic and lipolytic properties. The detection of GH abuse is challenging because it is an endogenous…”
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Combined growth hormone/insulin-like growth factor I in addition to glutamine-supplemented TPN results in net protein anabolism in critical illness by Carroll, Paul V, Jackson, Nicola C, Russell-Jones, David L, Treacher, David F, Sönksen, Peter H, Umpleby, A Margot

“…Protein loss leading to reduced lean body mass is recognized to contribute to the high levels of morbidity and mortality seen in critical illness. This…”
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Use and misuse of hormones in sport by Sonksen, Peter H, Cowan, David, Holt, Richard I G

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The history of doping and growth hormone abuse in sport by Holt, Richard I.G, Erotokritou-Mulligan, Ioulietta, Sönksen, Peter H

“…Abstract The earliest records of doping in sport come from the Ancient Olympics games when athletes are reported to have taken figs to improve their…”
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