Search Results - "Sonja Schmidt"
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An optimized low-pressure tourniquet murine hind limb ischemia reperfusion model: Inducing acute ischemia reperfusion injury in C57BL/6 wild type mice
Published in PloS one (24-01-2019)“…Acute ischemia reperfusion injury in skeletal muscle remains an important issue in several fields of regenerative medicine. Thus, a valid model is essential to…”
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Inflammatory processes and elevated osteoclast activity chaperon atrophic non-union establishment in a murine model
Published in Journal of translational medicine (12-12-2019)“…Delayed bone healing, especially in long bones poses one of the biggest problems in orthopeadic and reconstructive surgery and causes tremendous costs every…”
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A New Printable Alginate/Hyaluronic Acid/Gelatin Hydrogel Suitable for Biofabrication of In Vitro and In Vivo Metastatic Melanoma Models
Published in Advanced functional materials (01-01-2022)“…Two‐dimensional (2D) cancer models have been the standard for drug development over the past few years, but they frequently do not resemble in vivo properties…”
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Transcription factor activating enhancer-binding protein 2ε (AP2ε) modulates phenotypic plasticity and progression of malignant melanoma
Published in Cell death & disease (21-05-2024)“…Malignant melanoma, the most aggressive form of skin cancer, is often incurable once metastatic dissemination of cancer cells to distant organs has occurred…”
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Contributions of roots and rootstocks to sustainable, intensified crop production
Published in Journal of experimental botany (01-03-2013)“…Sustainable intensification is seen as the main route for meeting the world’s increasing demands for food and fibre. As demands mount for greater efficiency in…”
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Microscale heterogeneity explains experimental variability and non-linearity in soil organic matter mineralisation
Published in PloS one (19-05-2015)“…Soil respiration represents the second largest CO2 flux from terrestrial ecosystems to the atmosphere, and a small rise could significantly contribute to…”
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Tumor Cells Develop Defined Cellular Phenotypes After 3D-Bioprinting in Different Bioinks
Published in Cells (Basel, Switzerland) (22-10-2019)“…Malignant melanoma is often used as a model tumor for the establishment of novel therapies. It is known that two-dimensional (2D) culture methods are not…”
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Alpha1-antitrypsin improves survival in murine abdominal sepsis model by decreasing inflammation and sequestration of free heme
Published in Frontiers in immunology (18-03-2024)“…Excessive inflammation, hemolysis, and accumulation of labile heme play an essential role in the pathophysiology of multi-organ dysfunction syndrome (MODS) in…”
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SGLT2 Inhibition by Intraperitoneal Dapagliflozin Mitigates Peritoneal Fibrosis and Ultrafiltration Failure in a Mouse Model of Chronic Peritoneal Exposure to High-Glucose Dialysate
Published in Biomolecules (Basel, Switzerland) (19-11-2020)“…Peritoneal dialysis (PD) is limited by glucose-mediated peritoneal membrane (PM) fibrosis, angiogenesis, and ultrafiltration failure. Influencing PM integrity…”
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Comparison of Hydrogels for the Development of Well-Defined 3D Cancer Models of Breast Cancer and Melanoma
Published in Cancers (17-08-2020)“…Bioprinting offers the opportunity to fabricate precise 3D tumor models to study tumor pathophysiology and progression. However, the choice of the bioink used…”
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Absence of lymphatic vessels in term placenta
Published in BMC pregnancy and childbirth (29-06-2020)“…There has been debate about the existence of lymphatic vessels in placenta. Lymphatic endothelial cell (LEC) markers such as LYVE-1 and podoplanin/D2-40 have…”
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A vascularized in vivo melanoma model suitable for metastasis research of different tumor stages using fundamentally different bioinks
Published in Materials today bio (01-06-2024)“…Although 2D cancer models have been the standard for drug development, they don't resemble in vivo properties adequately. 3D models can potentially overcome…”
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Myostatin Upregulation in Patients in the Chronic Phase of Severe Burn Injury Leads to Muscle Cell Catabolism
Published in European surgical research (01-01-2019)“…Burn injury leads to a hypercatabolic response and ultimately muscle wasting with drastic implications for recovery of bodily functions, patient's quality of…”
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Molecular Changes Induced in Melanoma by Cell Culturing in 3D Alginate Hydrogels
Published in Cancers (15-08-2021)“…Alginate hydrogels have been used as a biomaterial for 3D culturing for several years. Here, gene expression patterns in melanoma cells cultivated in 3D…”
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Caries prevalence (ICDAS) in 12-year-olds from low caries prevalence areas and association with independent variables
Published in International journal of paediatric dentistry (01-03-2014)“…Background In areas with low caries prevalence, indices are needed for caries detection, which can also be used to identify initial lesions. Aim The aim of…”
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Tailoring Confinement: Nano-Carrier Synthesis via Z-RAFT Star Polymerization
Published in Polymers (01-04-2015)“…A new pathway to nano-sized hollow-sphere particles from six-arm star polymers with an amphiphilic core-corona structure, synthesized in a four-step-procedure…”
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Eph receptor tyrosine kinases in tumor and tumor microenvironment
Published in Current pharmaceutical design (01-01-2004)“…Eph receptors are a unique family of receptor tyrosine kinases (RTK) that play critical roles in embryonic patterning, neuronal targeting, and vascular…”
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Population structure of Tunisian Leishmania infantum and evidence for the existence of hybrids and gene flow between genetically different populations
Published in International journal for parasitology (01-06-2009)“…Twenty-seven strains of Leishmania infantum from north and central Tunisia belonging to the three main MON zymodemes (the MON-typing system is based on…”
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Discriminatory Role of Detergent-Resistant Membranes in the Dimerization and Endocytosis of Prostate-Specific Membrane Antigen
Published in PloS one (19-06-2013)“…Prostate-specific membrane antigen (PSMA) is a type-II membrane glycoprotein that was initially identified in LNCaP cells. It is expressed at elevated levels…”
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Reactions of the melatonin metabolite AMK (N1-acetyl-5-methoxykynuramine) with reactive nitrogen species: Formation of novel compounds, 3-acetamidomethyl-6-methoxycinnolinone and 3-nitro-AMK
Published in Journal of pineal research (01-10-2005)“…: The melatonin metabolite N1‐acetyl‐5‐methoxykynuramine (AMK) was found to be unstable in air when adsorbed on a thin‐layer silica gel chromatography plate,…”
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