Search Results - "Sonis, Stephen T."

The broadening scope of oral mucositis and oral ulcerative mucosal toxicities of anticancer therapies by Elad, Sharon, Yarom, Noam, Zadik, Yehuda, Kuten‐Shorrer, Michal, Sonis, Stephen T.

“…Oral mucositis (OM) is a common, highly symptomatic complication of cancer therapy that affects patients' function, quality of life, and ability to tolerate…”
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Mucositis: The impact, biology and therapeutic opportunities of oral mucositis by Sonis, Stephen T

“…Summary The history of mucositis is as old as radiation- and chemotherapy. Despite being regularly reported and documented as one of the worst side effects of…”
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Radiotherapy-induced severe oral mucositis: pharmacotherapies in recent and current clinical trials by Villa, Alessandro, Sonis, Stephen T

“…Oral mucositis (OM) is among the most common, damaging side effects of head and neck radiation therapy and may interfere with patients' ability to comply with…”
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Pharmacotherapy for the management of cancer regimen-related oral mucositis by Villa, Alessandro, Sonis, Stephen T

“…Oral mucositis is a frequent and devastating toxicity secondary to cancer treatment, which may affect 20-40% of patients receiving conventional chemotherapy…”
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New Frontiers in the Pathobiology and Treatment of Cancer Regimen-Related Mucosal Injury by Cinausero, Marika, Aprile, Giuseppe, Ermacora, Paola, Basile, Debora, Vitale, Maria G, Fanotto, Valentina, Parisi, Giuseppe, Calvetti, Lorenzo, Sonis, Stephen T

“…Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It often affects compliance to anticancer therapies as it frequently…”
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Cytokine‐mediated blood brain barrier disruption as a conduit for cancer/chemotherapy‐associated neurotoxicity and cognitive dysfunction by Wardill, Hannah R., Mander, Kimberley A., Van Sebille, Ysabella Z.A., Gibson, Rachel J., Logan, Richard M., Bowen, Joanne M., Sonis, Stephen T.

“…Neurotoxicity is a common side effect of chemotherapy treatment, with unclear molecular mechanisms. Clinical studies suggest that the most frequent neurotoxic…”
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Precision medicine for risk prediction of oral complications of cancer therapy–The example of oral mucositis in patients receiving radiation therapy for cancers of the head and neck by Sonis, Stephen T.

“…Oral complications of cancer therapy are common, markedly symptomatic, negatively impact patients' quality of life, and add significantly to the cost of care…”
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GM-1111 reduces radiation-induced oral mucositis in mice by targeting pattern recognition receptor-mediated inflammatory signaling by Pulsipher, Abigail, Savage, Justin R, Kennedy, Thomas P, Gupta, Kavita, Cuiffo, Benjamin G, Sonis, Stephen T, Lee, Won Yong

“…Oral mucositis (OM) is a common, painful side effect of radiation therapy used for the treatment of head and neck cancer (HNC). Activation of the innate immune…”
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Management of Oral Mucositis in Patients Who Have Cancer by Lalla, Rajesh V., BDS, PhD, CCRP, Sonis, Stephen T., DMD, DMSc, Peterson, Douglas E., DMD, PhD

“…Oral mucositis is a clinically important and sometimes dose-limiting complication of cancer therapy. Mucositis lesions can be painful, affect nutrition and…”
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The Chicken or the Egg? Changes in Oral Microbiota as Cause or Consequence of Mucositis During Radiation Therapy by Sonis, Stephen T.

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Updated clinical practice guidelines for the prevention and treatment of mucositis by Keefe, Dorothy M., Schubert, Mark M., Elting, Linda S., Sonis, Stephen T., Epstein, Joel B., Raber‐Durlacher, Judith E., Migliorati, Cesar A., McGuire, Deborah B., Hutchins, Ronald D., Peterson, Douglas E.

“…Considerable progress in research and clinical application has been made since the original guidelines for managing mucositis in cancer patients were published…”
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Treatment-related gastrointestinal toxicities and advanced colorectal or pancreatic cancer:A critical update by Aprile, Giuseppe, Rihawi, Karim, De Carlo, Elisa, Sonis, Stephen T

“…Gastrointestinal toxicities(GIT), including oral mucositis,nausea and vomiting, and diarrhea, are common side effects of chemotherapy and targeted agents in…”
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Monte Carlo based dosimetry of extraoral photobiomodulation for prevention of oral mucositis by Yaroslavsky, Anna N., Iorizzo, Tyler W., Juliano, Amy F., Adnan, Ather, Carroll, James D., Sonis, Stephen T., Duncan, Christine N., London, Wendy B., Treister, Nathaniel S.

“…Photobiomodulation therapy (PBMT) is recommended for prevention and treatment of oral mucositis, a painful condition that occurs in cancer patients. Intraoral…”
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Mechanisms of cellular fibrosis associated with cancer regimen-related toxicities by Mancini, Maria L, Sonis, Stephen T

“…Fibrosis is a common, persistent and potentially debilitating complication of chemotherapy and radiation regimens used for the treatment of cancer. The…”
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The Use of Hyperbaric Oxygen for the Prevention and Management of Osteoradionecrosis of the Jaw: A Dana‐Farber/Brigham and Women's Cancer Center Multidisciplinary Guideline by Sultan, Ahmed, Hanna, Glenn J., Margalit, Danielle N., Chau, Nicole, Goguen, Laura A., Marty, Francisco M., Rabinowits, Guilherme, Schoenfeld, Jonathan D., Sonis, Stephen T., Thomas, Tom, Tishler, Roy B., Treister, Nathaniel S., Villa, Alessandro, Woo, Sook‐Bin, Haddad, Robert, Mawardi, Hani

“…Background Osteoradionecrosis of the jaw (ORN) is an infrequent yet potentially devastating complication of radiation therapy to the head and neck region…”
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Topical Application of the Synthetic Triterpenoid RTA 408 Protects Mice from Radiation-Induced Dermatitis by Reisman, Scott A., Lee, Chun-Yue I., Meyer, Colin J., Proksch, Joel W., Sonis, Stephen T., Ward, Keith W.

“…Free radicals produced during cancer radiotherapy often leads to dermatitis, with the insult ranging from mild erythema to moist desquamation and ulceration…”
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Clinical practice guidelines for the prevention and treatment of cancer therapy–induced oral and gastrointestinal mucositis by Rubenstein, Edward B., Peterson, Douglas E., Schubert, Mark, Keefe, Dorothy, McGuire, Deborah, Epstein, Joel, Elting, Linda S., Fox, Philip C., Cooksley, Catherine, Sonis, Stephen T.

“…BACKGROUND Oral and gastrointestinal (GI) mucositis can affect up to 100% of patients undergoing high‐dose chemotherapy and hematopoietic stem cell…”
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Bardoxolone methyl analogs RTA 405 and dh404 are well tolerated and exhibit efficacy in rodent models of Type 2 diabetes and obesity by Chin, Melanie, Lee, Chun-Yue Ivy, Chuang, Jen-Chieh, Bumeister, Ron, Wigley, W Christian, Sonis, Stephen T, Ward, Keith W, Meyer, Colin

“…Bardoxolone methyl and related triterpenoids are well tolerated and efficacious in numerous animal models potentially relevant to patients with Type 2 diabetes…”
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Robust pathway sampling in phenotype prediction. Application to triple negative breast cancer by Cernea, Ana, Fernández-Martínez, Juan Luis, deAndrés-Galiana, Enrique J, Fernández-Ovies, Francisco Javier, Alvarez-Machancoses, Oscar, Fernández-Muñiz, Zulima, Saligan, Leorey N, Sonis, Stephen T

“…Phenotype prediction problems are usually considered ill-posed, as the amount of samples is very limited with respect to the scrutinized genetic probes. This…”
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Local and Systemic Pathogenesis and Consequences of Regimen-Induced Inflammatory Responses in Patients with Head and Neck Cancer Receiving Chemoradiation by Russi, Elvio G., Raber-Durlacher, Judith E., Sonis, Stephen T.

“…Treatment-related toxicities are common among patients with head and neck cancer, leading to poor clinical outcomes, reduced quality of life, and increased use…”
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