Search Results - "Sonis, S. T."

New thoughts on the initiation of mucositis by Sonis, ST

“…Oral Diseases (2010) 16, 597–600 It has been slightly more than a decade since the classic mechanistic paradigm that defined the pathogenesis of mucositis was…”
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Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action by Wardill, H. R., Sonis, S. T., Blijlevens, N. M. A., Van Sebille, Y. Z. A., Ciorba, M. A., Loeffen, E. A. H., Cheng, K. K. F., Bossi, P., Porcello, L., Castillo, D. A., Elad, S., Bowen, J. M.

“…Purpose Despite advances in personalizing the efficacy of cancer therapy, our ability to identify patients at risk of severe treatment side effects and provide…”
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Ultrasound‐mediated drug delivery by Sonis, ST

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Host-Microbiome Cross-talk in Oral Mucositis by Vasconcelos, R.M., Sanfilippo, N., Paster, B.J., Kerr, A.R., Li, Y., Ramalho, L., Queiroz, E.L., Smith, B., Sonis, S.T., Corby, P.M.

“…Oral mucositis (OM) is among the most common, painful, and debilitating toxicities of cancer regimen–related treatment, resulting in the formation of ulcers,…”
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Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity by Sonis, S.T

“…Mucositis induced by antineoplastic drugs is an important, dose-limiting and costly side effect of cancer therapy. The ulcerative lesions which result are…”
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Oral Mucositis and the Clinical and Economic Outcomes of Hematopoietic Stem-Cell Transplantation by SONIS, Stephen T, OSTER, Gerry, MILLER, Carole, PETERSON, Douglas E, SCHUBERT, Mark M, SPIJKERVET, Frederik K. L, HOROWITZ, Mary, FUCHS, Hank, BELLM, Lisa, BRADFORD, Williamson Z, EDELSBERG, John, HAYDEN, Vanessa, EILERS, June, EPSTEIN, Joel B, LEVEQUE, Francis G

“…To explore the relationship between oral mucositis and selected clinical and economic outcomes in blood and marrow transplant patients. Subjects consisted of…”
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Placebo effect in burning mouth syndrome: a systematic review by Kuten-Shorrer, M, Kelley, JM, Sonis, ST, Treister, NS

“…Placebo controls play a critical role in the evaluation of any pharmacotherapy. This review surveys the placebo arm in 12 randomized controlled trials (RCTs)…”
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Subgingival and Tongue Microbiota during Early Periodontitis by Tanner, A.C.R., Paster, B.J., Lu, S.C., Kanasi, E., Kent, R., Van Dyke, T., Sonis, S.T.

“…Periodontal infections have a microbial etiology. Association of species with early disease would be useful in determining which microbes initiate…”
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The relationship between mucosal cyclooxygenase-2 (COX-2) expression and experimental radiation-induced mucositis by Sonis, S.T., O'Donnell, K.E., Popat, R., Bragdon, C., Phelan, S., Cocks, D., Epstein, J.B.

“…Although cycloooxygenase-2 (COX-2) is upregulated by factors associated with oral mucositis, its role in the pathogenesis of mucositis has not been studied. We…”
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Defining mechanisms of action of interleukin-11 on the progression of radiation-induced oral mucositis in hamsters by Sonis, S.T, Peterson, R.L, Edwards, L.J, Lucey, C.A, Wang, L, Mason, L, Login, G, Ymamkawa, M, Moses, G, Bouchard, P, Hayes, L.L, Bedrosian, C, Dorner, A.J

“…Oral ulcerative mucositis is a common toxicity associated with drug and radiation therapy for cancer. It impacts on quality of life and economic outcomes, as…”
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Assessment of oral mucositis in clinical trials: Impact of training on evaluators in a multi-centre trial by Stokman, M.A., Sonis, S.T., Dijkstra, P.U., Burgerhof, J.G.M., Spijkervet, F.K.L.

“…In the assessment of mucositis, the inter-evaluator variability needs to be minimised and would likely to be best accomplished by training. The aim of this…”
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The gene expression sequence of radiated mucosa in an animal mucositis model by Sonis, S. T., Scherer, J., Phelan, S., Lucey, C. A., Barron, J. E., O'Donnell, K. E., Brennan, R. J., Pan, H., Busse, P., Haley, J. D.

“… Oral mucositis is a common, dose‐limiting, acute toxicity of radiation therapy administered for the treatment of cancers of the head and neck. Accumulating…”
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A longitudinal study of oral ulcerative mucositis in bone marrow transplant recipients by Woo, S B, Sonis, S T, Monopoli, M M, Sonis, A L

“…Few longitudinal studies have investigated the onset, duration, and resolution of ulcerative mucositis in bone marrow transplant recipients. This study…”
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The pathobiology of mucositis by Sonis, Stephen T

“…Oral and gastrointestinal mucositis is a toxicity of many forms of radiotherapy and chemotherapy. It has a significant impact on health, quality of life and…”
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SNP-based Bayesian networks can predict oral mucositis risk in autologous stem cell transplant recipients by Sonis, ST, Antin, JH, Tedaldi, MW, Alterovitz, G

“…Objective Approximately 40% of patients receiving conditioning chemotherapy prior to autologous hematopoietic stem cell transplants (aHSCT) develop severe oral…”
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IL-11, a pleiotropic cytokine: exciting new effects of IL-11 on gastrointestinal mucosal biology by Keith, Jr, J C, Albert, L, Sonis, S T, Pfeiffer, C J, Schaub, R G

“…Recombinant human interleukin 11 (rhIL-11) is a pleiotropic cytokine that stimulates bone marrow stem cells to proliferate and decreases intestinal mucosal…”
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The impact of mucositis on α‐hemolytic streptococcal infection in patients undergoing autologous bone marrow transplantation for hematologic malignancies by Ruescher, Thomas J., Sodeifi, Alireza, Scrivani, Steven J., Kaban, Leonard B., Sonis, Stephen T.

“…BACKGROUND Antibacterial prophylaxis with quinolone antibiotics has resulted in an increase in streptococcal infections among bone marrow transplantation (BMT)…”
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Transplantation of polarized type 2 donor T cells reduces mortality caused by experimental graft-versus-host disease by KRENGER, W, COOKE, K. R, CRAWFORD, J. M, SONIS, S. T, SIMMONS, R, PAN, L, DELMONTE, J. JR, KARANDIKAR, M, FERRARA, J. L. M

“…Acute graft-versus-host disease (GVHD) is thought to be initiated by alloreactive type 1 T cells that secrete gamma-interferon (IFN-gamma). IFN-gamma induces…”
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Bony changes in the jaws of rats treated with zoledronic acid and dexamethasone before dental extractions mimic bisphosphonate-related osteonecrosis in cancer patients by Sonis, Stephen T, Watkins, Brynmor A, Lyng, Gregory D, Lerman, Mark A, Anderson, Kenneth C

“…Summary Osteonecrosis of the jaw is associated with aminobisphosphonate use in patients treated with intravenous doses for the prevention of bony metastases. A…”
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Validation of a new scoring system for the assessment of clinical trial research of oral mucositis induced by radiation or chemotherapy by Sonis, Stephen T., Eilers, June P., Epstein, Joel B., LeVeque, Francis G., Liggett, William H., Mulagha, Mary T., Peterson, Douglas E., Rose, Ann H., Schubert, Mark M., Spijkervet, Frederik K., Wittes, Janet P.

“…BACKGROUND An impediment to mucositis research has been the lack of an accepted, validated scoring system. The objective of this study was to design, test, and…”
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