Search Results - "Sonia Volpi"
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Does cystic fibrosis constitute an advantage in COVID-19 infection?
Published in Italian journal of pediatrics (06-10-2020)“…The Veneto region is one of the most affected Italian regions by COVID-19. Chronic lung diseases, such as chronic obstructive pulmonary disease (COPD), may…”
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SARS-CoV-2 viral entry and replication is impaired in Cystic Fibrosis airways due to ACE2 downregulation
Published in Nature communications (10-01-2023)“…As an inherited disorder characterized by severe pulmonary disease, cystic fibrosis could be considered a comorbidity for coronavirus disease 2019. Instead,…”
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Use of mucoactive agents in cystic fibrosis: A consensus survey of Italian specialists
Published in Health science reports (01-07-2022)“…Background The goal of mucoactive therapies in cystic fibrosis (CF) is to enhance sputum clearance and to reduce a progressive decline in lung function over…”
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Toothbrushes may convey bacteria to the cystic fibrosis lower airways
Published in Journal of oral microbiology (01-01-2019)“…Recent findings indicate that the oral cavity acts as a bacterial reservoir and might contribute to the transmission of bacteria to the lower airways. Control…”
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Relationship Between Lung Volumes and Heterogeneity in the Response to Elexacaftor/Tezacaftor/Ivacaftor in Patients With Cystic Fibrosis and Advanced Lung Disease
Published in Chest (01-09-2024)“…The effects of elexacaftor/tezacaftor/ivacaftor (ETI) on respiratory outcomes for people with cystic fibrosis (CF) were demonstrated by several clinical…”
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A longitudinal study of glucose tolerance in cystic fibrosis: the central role of beta cell functional mass
Published in The journal of clinical endocrinology and metabolism (12-07-2024)“…The pathophysiological mechanisms underlying the natural history of glucose intolerance and its fluctuations in subjects with cystic fibrosis (CF) are still…”
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Delayed age at menarche in chronic respiratory diseases
Published in European journal of clinical investigation (01-05-2021)“…Objective Age at menarche (AAM) is an important indicator of physiological development in women, and delayed AAM has been associated with chronic illnesses. We…”
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Long-term clinical outcomes of elexacaftor/tezacaftor/ivacaftor therapy in adults with cystic fibrosis and advanced pulmonary disease
Published in Respiratory medicine (01-11-2023)“…The combination of cystic fibrosis transmembrane conductance regulator (CFTR) modulators elexacaftor, tezacaftor and ivacaftor (ELX/TEZ/IVA) has been approved…”
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Glucose Tolerance Stages in Cystic Fibrosis Are Identified by a Unique Pattern of Defects of Beta-Cell Function
Published in The journal of clinical endocrinology and metabolism (01-04-2021)“…Abstract Objective We aimed to assess the order of severity of the defects of 3 direct determinants of glucose regulation—beta-cell function, insulin…”
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The non-invasive evaluation of vascular liver disease in patients with cystic fibrosis: a prospective cross-sectional study
Published in Journal of hepatology (01-06-2023)Get full text
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THU-293 - The non-invasive evaluation of vascular liver disease in patients with cystic fibrosis: a prospective cross-sectional study
Published in Journal of hepatology (01-06-2023)Get full text
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Inconclusive diagnosis of cystic fibrosis after newborn screening
Published in Pediatrics (Evanston) (01-06-2015)“…To prospectively study infants with an inconclusive diagnosis of cystic fibrosis (CF) identified by newborn screening (NBS; "CF screen positive, inconclusive…”
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The non‐invasive evaluation of liver involvement in patients with cystic fibrosis: A prospective study
Published in Liver international (01-11-2023)“…Background and AimsPorto‐sinusoidal vascular disease (PSVD) has been described as the prominent pathology in liver explants of patients with cystic fibrosis…”
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Age at menarche in girls with cystic fibrosis and asthma
Published in Minerva endocrinology (01-12-2022)Get more information
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The effect of inhaled hypertonic saline on lung structure in children aged 3–6 years with cystic fibrosis (SHIP-CT): a multicentre, randomised, double-blind, controlled trial
Published in The lancet respiratory medicine (01-07-2022)“…In the Saline Hypertonic in Preschoolers (SHIP) study, inhaled 7% hypertonic saline improved the lung clearance index in children aged 3–6 years with cystic…”
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Impact of CFTR Modulators on Beta-Cell Function in Children and Young Adults with Cystic Fibrosis
Published in Journal of clinical medicine (17-07-2022)“…Background: To date, no consistent data are available on the possible impact of CFTR modulators on glucose metabolism. The aim of this study was to test the…”
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Lung function comparison between two decades in cystic fibrosis children: A single centre study
Published in Pediatric pulmonology (01-12-2015)“…Summary Objectives The purpose of this study was to compare two cohorts of cystic fibrosis (CF) patients born and treated in two different decades, diagnosed…”
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Growth and long-term lung function in cystic fibrosis: A longitudinal study of patients diagnosed by neonatal screening
Published in Pediatric pulmonology (01-03-2009)“…Objective So far there is no long‐term analysis relating the achievement of growth milestones (such as prepubertal and pubertal take‐off and peak velocity) to…”
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In silico analysis and theratyping of an ultra-rare CFTR genotype (W57G/A234D) in primary human rectal and nasal epithelial cells
Published in iScience (17-11-2023)“…Mutation targeted therapy in cystic fibrosis (CF) is still not eligible for all CF subjects, especially for cases carrying rare variants such as the CFTR…”
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