Search Results - "Soni, Sanooj"

Clinical and survival differences during separate COVID-19 surges: Investigating the impact of the Sars-CoV-2 alpha variant in critical care patients by Ritchie, Andrew I, Kadwani, Owais, Saleh, Dina, Baharlo, Behrad, Broomhead, Lesley R, Randell, Paul, Waheed, Umeer, Templeton, Maie, Brown, Elizabeth, Stümpfle, Richard, Patel, Parind, Brett, Stephen J, Soni, Sanooj

“…A number of studies have highlighted physiological data from the first surge in critically unwell Covid-19 patients but there is a paucity of data describing…”
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Microvesicle-Mediated Communication Within the Alveolar Space: Mechanisms of Uptake by Epithelial Cells and Alveolar Macrophages by Soni, Sanooj, O'Dea, Kieran P, Abe, Eiko, Khamdan, Maryam, Shah, Sneh V, Sarathchandra, Padmini, Wilson, Michael R, Takata, Masao

“…Intra-alveolar microvesicles (MVs) are important mediators of inter-cellular communication within the alveolar space, and are key components in the…”
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Monocytes mediate homing of circulating microvesicles to the pulmonary vasculature during low-grade systemic inflammation by O'Dea, Kieran P., Tan, Ying Ying, Shah, Sneh, V Patel, Brijesh, C Tatham, Kate, Wilson, Mike R., Soni, Sanooj, Takata, Masao

“…Microvesicles (MVs), a plasma membrane-derived subclass of extracellular vesicles, are produced and released into the circulation during systemic inflammation,…”
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Alveolar macrophage-derived microvesicles mediate acute lung injury by Soni, Sanooj, Wilson, Michael R, O'Dea, Kieran P, Yoshida, Mariko, Katbeh, Umar, Woods, Samantha J, Takata, Masao

“…Microvesicles (MVs) are important mediators of intercellular communication, packaging a variety of molecular cargo. They have been implicated in the…”
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Conservative versus Liberal Oxygen Therapy by Watson, Naomi, Brown, Elizabeth, Ritchie, Andrew I., Soni, Sanooj

“…Watson discusses the study by D. Mackle and colleagues on conservative oxygen therapy during mechanical ventilation in the intensive care unit (ICU). The…”
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Analysis of Critical Care Severity of Illness Scoring Systems in Patients With Coronavirus Disease 2019: A Retrospective Analysis of Three U.K. ICUs by Stephens, Jonny R., Stümpfle, Richard, Patel, Parind, Brett, Stephen, Broomhead, Robert, Baharlo, Behrad, Soni, Sanooj

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The Video Classification of Intubation (VCI) score: a new description tool for tracheal intubation using videolaryngoscopy: A pilot study by Chaggar, Rajinder Singh, Shah, Sneh Vinu, Berry, Michael, Saini, Rajan, Soni, Sanooj, Vaughan, David

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Reply to comment about the Video Classification of Intubation (VCI) score: a new description tool for tracheal intubation using videolaryngoscopy: a pilot study by Chaggar, Rajinder Singh, Shah, Sneh Vinu, Berry, Michael, Saini, Rajan, Soni, Sanooj, Vaughan, David

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Reply to comment about The Video Classification of Intubation score: a new description tool for tracheal intubation using videolaryngoscopy: A pilot study by Chaggar, Rajinder Singh, Shah, Sneh Vinu, Berry, Michael, Saini, Rajan, Soni, Sanooj, Vaughan, David

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ATP redirects cytokine trafficking and promotes novel membrane TNF signaling via microvesicles by Soni, Sanooj, O'Dea, Kieran P., Tan, Ying Ying, Cho, Kahori, Abe, Eiko, Romano, Rosalba, Cui, Jiang, Ma, Daqing, Sarathchandra, Padmini, Wilson, Michael R., Takata, Masao

“…ABSTRACTCellular stress or injury induces release of endogenous danger signals such as ATP, which plays a central role in activating immune cells. ATP is…”
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Recommended Reading from the Imperial College, London Fellows by Watson, Naomi, Brown, Elizabeth, Ritchie, Andrew I, Soni, Sanooj

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Ventilator-induced Lung Injury Promotes Inflammation within the Pleural Cavity by Baldi, Rhianna F, Koh, Marissa W, Thomas, Chubicka, Sabbat, Tomasz, Wang, Bincheng, Tsatsari, Stefania, Young, Kieron, Wilson-Slomkowski, Alexander, Soni, Sanooj, O'Dea, Kieran P, Patel, Brijesh V, Takata, Masao, Wilson, Michael R

“…Mechanical ventilation contributes to the morbidity and mortality of patients in intensive care, likely through the exacerbation and dissemination of…”
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One hundred eighteen days on a ventilator: a COVID-19 success story against all odds by Chia, Germaine, Barrett, Hannah, Patel, Parind, Soni, Sanooj

“…Emerging data suggest that patients with certain comorbidities requiring intensive care unit (ICU) admission for COVID-19 have a poor prognosis. This report…”
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Intra-alveolar neutrophil-derived microvesicles are associated with disease severity in COPD by Soni, Sanooj, Garner, Justin L, O'Dea, Kieran P, Koh, Marissa, Finney, Lydia, Tirlapur, Nikhil, Srikanthan, Karthi, Tenda, Eric D, Aboelhassan, Arafa M, Singh, Suveer, Wilson, Michael R, Wedzicha, Jadwiga A, Kemp, Samuel V, Usmani, Omar S, Shah, Pallav L, Takata, Masao

“…Despite advances in the pathophysiology of chronic obstructive pulmonary disease (COPD), there is a distinct lack of biochemical markers to aid clinical…”
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Secreted Extracellular Cyclophilin A Is a Novel Mediator of Ventilator-induced Lung Injury by Koh, Marissa W, Baldi, Rhianna F, Soni, Sanooj, Handslip, Rhodri, Tan, Ying Ying, O'Dea, Kieran P, Malesevic, Miroslav, McAuley, Daniel F, O'Kane, Cecilia M, Patel, Brijesh V, Takata, Masao, Wilson, Michael R

“…Mechanical ventilation is a mainstay of intensive care but contributes to the mortality of patients through ventilator-induced lung injury. eCypA…”
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Ventilation following established ARDS: a preclinical model framework to improve predictive power by Oakley, Charlotte, Koh, Marissa, Baldi, Rhianna, Soni, Sanooj, O'Dea, Kieran, Takata, Masao, Wilson, Michael

“…Despite advances in understanding the pathophysiology of acute respiratory distress syndrome, effective pharmacological interventions have proven elusive. We…”
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Enhanced Recognition and Internalisation of Microvesicles by Lung‐Marginated, Ly‐6C high Monocytes During Endotoxaemia by Tan, Ying Ying, O'Dea, Kieran Patrick, Soni, Sanooj, Shah, Sneh, Patel, Brijesh Vipinchandra, Takata, Masao

“…Background Circulating microvesicles (MVs) have been implicated as long‐range mediators of vascular inflammation, but their precise role in the pathophysiology…”
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Microvesicles as new therapeutic targets for the treatment of the acute respiratory distress syndrome (ARDS) by Soni, Sanooj, Tirlapur, Nikhil, O'Dea, Kieran P, Takata, Masao, Wilson, Michael R

“…: Acute respiratory distress syndrome (ARDS) is a heterogeneous and multifactorial disease; it is a common and devastating condition that has a high mortality…”
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Microvesicles are key mediators of inflammation in acute lung injury by Soni, Sanooj

“…Acute lung injury (ALI) and its clinical presentation Acute Respiratory Distress Syndrome (ARDS) has an unacceptably high mortality, surpassing 40% in those…”
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Flecainide overdose causing a Brugada-type pattern on electrocardiogram in a previously well patient by Soni, Sanooj, Gandhi, Sandeep

“…Since its definition in 1992, Brugada syndrome has been identified as the most common cause of natural death in men younger than 50 years in parts of Asia…”
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