Search Results - "Soni, Disha M."

Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer’s Disease-Relevant Phenotypes in Mice by Oblak, Adrian L., Kotredes, Kevin P., Pandey, Ravi S., Reagan, Alaina M., Ingraham, Cynthia, Perkins, Bridget, Lloyd, Christopher, Baker, Deborah, Lin, Peter B., Soni, Disha M., Tsai, Andy P., Persohn, Scott A., Bedwell, Amanda A., Eldridge, Kierra, Speedy, Rachael, Meyer, Jill A., Peters, Johnathan S., Figueiredo, Lucas L., Sasner, Michael, Territo, Paul R., Sukoff Rizzo, Stacey J., Carter, Gregory W., Lamb, Bruce T., Howell, Gareth R.

“…Obesity is recognized as a significant risk factor for Alzheimer’s disease (AD). Studies have supported the notion that obesity accelerates AD-related…”
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SHIP1 therapeutic target enablement: Identification and evaluation of inhibitors for the treatment of late‐onset Alzheimer's disease by Jesudason, Cynthia D., Mason, Emily R., Chu, Shaoyou, Oblak, Adrian L., Javens‐Wolfe, June, Moussaif, Mustapha, Durst, Greg, Hipskind, Philip, Beck, Daniel E., Dong, Jiajun, Amarasinghe, Ovini, Zhang, Zhong‐Yin, Hamdani, Adam K., Singhal, Kratika, Mesecar, Andrew D., Souza, Sarah, Jacobson, Marlene, Salvo, Jerry Di, Soni, Disha M., Kandasamy, Murugesh, Masters, Andrea R., Quinney, Sara K, Doolen, Suzanne, Huhe, Hasi, Rizzo, Stacey J. Sukoff, Lamb, Bruce T., Palkowitz, Alan D., Richardson, Timothy I.

“…INTRODUCTION The risk of developing Alzheimer's disease is associated with genes involved in microglial function. Inositol polyphosphate‐5‐phosphatase…”
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Use of AD Informer Set compounds to explore validity of novel targets in Alzheimer's disease pathology by Potjewyd, Frances M., Annor‐Gyamfi, Joel K., Aubé, Jeffrey, Chu, Shaoyou, Conlon, Ivie L., Frankowski, Kevin J., Guduru, Shiva K. R., Hardy, Brian P., Hopkins, Megan D., Kinoshita, Chizuru, Kireev, Dmitri B., Mason, Emily R., Moerk, Charles T., Nwogbo, Felix, Pearce, Kenneth H., Richardson, Timothy I., Rogers, David A., Soni, Disha M., Stashko, Michael, Wang, Xiaodong, Wells, Carrow, Willson, Timothy M., Frye, Stephen V., Young, Jessica E., Axtman, Alison D.

“…Introduction A chemogenomic set of small molecules with annotated activities and implicated roles in Alzheimer's disease (AD) called the AD Informer Set was…”
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AD Informer Set: Chemical tools to facilitate Alzheimer's disease drug discovery by Potjewyd, Frances M., Annor‐Gyamfi, Joel K., Aubé, Jeffrey, Chu, Shaoyou, Conlon, Ivie L., Frankowski, Kevin J., Guduru, Shiva K. R., Hardy, Brian P., Hopkins, Megan D., Kinoshita, Chizuru, Kireev, Dmitri B., Mason, Emily R., Moerk, Charles T., Nwogbo, Felix, Pearce, Kenneth H., Richardson, Timothy I., Rogers, David A., Soni, Disha M., Stashko, Michael, Wang, Xiaodong, Wells, Carrow, Willson, Timothy M., Frye, Stephen V., Young, Jessica E., Axtman, Alison D.

“…Introduction The portfolio of novel targets to treat Alzheimer's disease (AD) has been enriched by the Accelerating Medicines Partnership Program for…”
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Microglial Phagocytosis/Cell Health High-Content Assay by Mason, Emily R, Soni, Disha M, Chu, Shaoyou

“…We report a microglial phagocytosis/cell health high-content assay that has been used to test small molecule chemical probes and support our drug discovery…”
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SHIP1 modulation and proteome characterization of microglia by Ahat, Erpan, Shi, Zanyu, Chu, Shaoyou, Bui, Hai Hoang, Mason, Emily R., Soni, Disha M., Roth, Kenneth D., Chalmers, Michael James, Oblak, Adrian L., Zhang, Jie, Gutierrez, Jesus A., Richardson, Timothy

“…Understanding microglial states in the aging brain has become crucial, especially with the discovery of numerous Alzheimer's disease (AD) risk and protective…”
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Inpp5d haplodeficiency alleviates tau pathology in the PS19 mouse model of Tauopathy by Soni, Disha M., Lin, Peter Bor‐Chian, Lee‐Gosselin, Audrey, Lloyd, Christopher D., Mason, Emily, Ingraham, Cynthia M., Perkins, Abigail, Moutinho, Miguel, Lamb, Bruce T., Chu, Shaoyou, Oblak, Adrian L.

“…INTRODUCTION A noncoding variant (rs35349669) within INPP5D, a lipid and protein phosphatase restricted to microglia in the brain, is linked to increased…”
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Plcg2 M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice by Oblak, Adrian L, Kotredes, Kevin P, Pandey, Ravi S, Reagan, Alaina M, Ingraham, Cynthia, Perkins, Bridget, Lloyd, Christopher, Baker, Deborah, Lin, Peter B, Soni, Disha M, Tsai, Andy P, Persohn, Scott A, Bedwell, Amanda A, Eldridge, Kierra, Speedy, Rachael, Meyer, Jill A, Peters, Johnathan S, Figueiredo, Lucas L, Sasner, Michael, Territo, Paul R, Sukoff Rizzo, Stacey J, Carter, Gregory W, Lamb, Bruce T, Howell, Gareth R

“…Obesity is recognized as a significant risk factor for Alzheimer's disease (AD). Studies have supported the notion that obesity accelerates AD-related…”
Get full text