Search Results - "Song, Yuanquan"
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Calcium channels caught in peripheral glia's tug-of-war on axon regeneration in Drosophila
Published in Neural regeneration research (01-02-2025)Get full text
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Glial Metabolic Rewiring Promotes Axon Regeneration and Functional Recovery in the Central Nervous System
Published in Cell metabolism (03-11-2020)“…Axons in the mature central nervous system (CNS) fail to regenerate after axotomy, partly due to the inhibitory environment constituted by reactive glial cells…”
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The Mechanosensitive Ion Channel Piezo Inhibits Axon Regeneration
Published in Neuron (Cambridge, Mass.) (17-04-2019)“…Neurons exhibit a limited ability of repair. Given that mechanical forces affect neuronal outgrowth, it is important to investigate whether mechanosensitive…”
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The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
Published in Nature communications (22-06-2021)“…Atr is a serine/threonine kinase, known to sense single-stranded DNA breaks and activate the DNA damage checkpoint by phosphorylating Chek1, which inhibits…”
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Non-canonical role of the ATR pathway in axon regeneration as a mechanosensitive brake
Published in Neural regeneration research (01-11-2022)Get full text
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A naturally monomeric infrared fluorescent protein for protein labeling in vivo
Published in Nature methods (01-08-2015)“…An infrared fluorescent protein based on a new monomeric scaffold is described in this paper and is tested for protein fusion in cells and in vivo. Infrared…”
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Epidermal cells are the primary phagocytes in the fragmentation and clearance of degenerating dendrites in Drosophila
Published in Neuron (Cambridge, Mass.) (05-02-2014)“…During developmental remodeling, neurites destined for pruning often degenerate on-site. Physical injury also induces degeneration of neurites distal to the…”
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Enzymatic hydrolysis and simultaneous saccharification and fermentation of alkali/peracetic acid-pretreated sugarcane bagasse for ethanol and 2,3-butanediol production
Published in Enzyme and microbial technology (10-09-2011)“…The enzymatic digestibility of alkali/peracetic acid (PAA)-pretreated bagasse was systematically investigated. The effects of initial solid consistency,…”
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Glia instruct axon regeneration via a ternary modulation of neuronal calcium channels in Drosophila
Published in Nature communications (14-10-2023)“…A neuron’s regenerative capacity is governed by its intrinsic and extrinsic environment. Both peripheral and central neurons exhibit cell-type-dependent axon…”
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Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila
Published in eLife (06-10-2020)“…Neuroregeneration is a dynamic process synergizing the functional outcomes of multiple signaling circuits. Channelrhodopsin-based optogenetics shows the…”
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Regulation of axon regeneration by the RNA repair and splicing pathway
Published in Nature neuroscience (01-06-2015)“…In this study, the authors show that the RNA repair and splicing pathway regulates axon regeneration in the nervous system of Drosophila . Rtca, a RNA cyclase,…”
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Neural and synaptic defects in slytherin, a zebrafish model for human congenital disorders of glycosylation
Published in PloS one (29-10-2010)“…Congenital disorder of glycosylation type IIc (CDG IIc) is characterized by mental retardation, slowed growth and severe immunodeficiency, attributed to the…”
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Mechanisms underlying metabolic and neural defects in zebrafish and human multiple acyl-CoA dehydrogenase deficiency (MADD)
Published in PloS one (17-12-2009)“…In humans, mutations in electron transfer flavoprotein (ETF) or electron transfer flavoprotein dehydrogenase (ETFDH) lead to MADD/glutaric aciduria type II, an…”
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PRODUCTION OF 2,3-BUTANEDIOL BY KLEBSIELLA PNEUMONIAE FROM ENZYMATIC HYDROLYZATE OF SUGARCANE BAGASSE
Published in Bioresources (01-01-2012)“…Fermentation conditions for 2,3-butanediol (2,3-BD) production by Klebsiella pneumoniae CGMCC1.9131 were optimized statistically in shake flasks. Four…”
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mll ortholog containing functional domains of human MLL is expressed throughout the zebrafish lifespan and in haematopoietic tissues
Published in British journal of haematology (01-02-2011)“…Summary Infant leukaemia is an embryonal disease in which the underlying MLL translocations initiate in utero. Zebrafish offer unique potential to understand…”
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All hands on deck: Adipocytes lept-in to drive nerve regeneration
Published in Cell metabolism (05-12-2023)“…The glial metabolic state instructs nerve regeneration. In this issue of Cell Metabolism, Sundaram, Schütza, Schröter, et al. demonstrate that nerve injury…”
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Mechanosensitive Ion Channels, Axonal Growth, and Regeneration
Published in The Neuroscientist (01-08-2023)“…Cells sense and respond to mechanical stimuli by converting those stimuli into biological signals, a process known as mechanotransduction. Mechanotransduction…”
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Book Review Journal Article -
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Drosophila Laser Axotomy Injury Model to Investigate RNA Repair and Splicing in Axon Regeneration
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…The limited axon regeneration capacity of mature neurons often leads to insufficient functional recovery after damage to the central nervous system (CNS). To…”
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A Feedforward Mechanism Mediated by Mechanosensitive Ion Channel PIEZO1 and Tissue Mechanics Promotes Glioma Aggression
Published in Neuron (Cambridge, Mass.) (21-11-2018)“…Alteration of tissue mechanical properties is a physical hallmark of solid tumors including gliomas. How tumor cells sense and regulate tissue mechanics is…”
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The microtubule regulator ringer functions downstream from the RNA repair/splicing pathway to promote axon regeneration
Published in The FASEB journal (01-04-2020)“…Abstract only Promoting axon regeneration in the central and peripheral nervous system is of clinical importance in neural injury and neurodegenerative…”
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