Search Results - "Song, Shan"
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Thioparib inhibits homologous recombination repair, activates the type I IFN response, and overcomes olaparib resistance
Published in EMBO molecular medicine (08-03-2023)“…Poly‐ADP‐ribose polymerase (PARP) inhibitors (PARPi) have shown great promise for treating BRCA‐deficient tumors. However, over 40% of BRCA‐deficient patients…”
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2
Lipid-Related Domestication Accounts for the Extreme Cold Sensitivity of Semiwild and Tropic Xishuangbanna Cucumber ( Cucumis sativus L. var. xishuangbannanesis )
Published in International journal of molecular sciences (20-12-2023)“…Xishuangbanna (XIS) cucumber ( L. var. ) is a semiwild variety originating from low latitude tropic areas, and therefore shows extreme cold sensitivity and…”
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3
Corrosion control of copper in 3.5 wt.% NaCl Solution by Domperidone: Experimental and Theoretical Study
Published in Corrosion science (01-08-2014)Get full text
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Increased PARP1‐DNA binding due to autoPARylation inhibition of PARP1 on DNA rather than PARP1‐DNA trapping is correlated with PARP1 inhibitor's cytotoxicity
Published in International journal of cancer (01-08-2019)“…PARP1 inhibitors (PARPis) are used clinically during cancer therapy and are thought to exert their cytotoxicity through PARP1 polymerase inhibition and…”
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5
Inhibition of NLRP3 inflammasome ameliorates podocyte damage by suppressing lipid accumulation in diabetic nephropathy
Published in Metabolism, clinical and experimental (01-05-2021)“…Nucleotide leukin-rich polypeptide 3 (NLRP3) inflammasome is documented as a potent target for treating metabolic diseases and inflammatory disorders. Our…”
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Glycogen synthase kinase 3β inhibition synergizes with PARP inhibitors through the induction of homologous recombination deficiency in colorectal cancer
Published in Cell death & disease (15-02-2021)“…Monotherapy with poly ADP-ribose polymerase (PARP) inhibitors results in a limited objective response rate (≤60% in most cases) in patients with homologous…”
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A Data Compression Method for Wellbore Stability Monitoring Based on Deep Autoencoder
Published in Sensors (Basel, Switzerland) (20-06-2024)“…The compression method for wellbore trajectory data is crucial for monitoring wellbore stability. However, classical methods like methods based on Huffman…”
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Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
Published in Biochemical pharmacology (01-05-2024)“…[Display omitted] Agents that inhibit bromodomain and extra-terminal domain (BET) proteins have been actively tested in the clinic as potential anticancer…”
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9
The gravitational baryogenesis and a new higher-order extended uncertainty principle with parameter adaptability for the minimum length
Published in Annals of physics (01-11-2023)Get full text
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10
Dissimilarity in sensory attributes, shelf life and spoilage bacterial and fungal microbiota of industrial-scale wet starch noodles induced by different preservatives and temperature
Published in Food research international (01-02-2021)“…[Display omitted] •Quality and shelf-life of new high-moisture food (wet starch noodles) is studied.•Combination of sodium dehydroacetate and 4 °C preserves…”
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Obstructive sleep apnea increases risk of female infertility: A 14-year nationwide population-based study
Published in PloS one (15-12-2021)“…To determine the risk of having OSA in a cohort of female subjects who are infertile and the odds of being infertile in women with OSA. A nationwide,…”
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Three-dimensional ZnO nanosheet spheres/graphene foam for electrochemical determination of levodopa in the presence of uric acid
Published in Journal of electroanalytical chemistry (Lausanne, Switzerland) (01-04-2019)“…The ZnO nanosheet spheres (ZnO NSSs) have been hydrothermally synthesized on the surface of graphene foam (GF). A series of characterization techniques, such…”
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13
Identification of YCH2823 as a novel USP7 inhibitor for cancer therapy
Published in Biochemical pharmacology (01-04-2024)“…[Display omitted] Inhibition of the human ubiquitin-specific protease 7 (USP7), the key deubiquitylating enzyme in regulating p53 protein levels, has been…”
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Chiral Imidodiphosphoric Acids-Catalyzed Friedel-Crafts Reactions of Indoles/Pyrroles with 3-Hydroxy-indolyloxindoles: Enantioselective Synthesis of 3,3-Diaryloxindoles
Published in Advanced synthesis & catalysis (03-03-2016)“…The first enantioselective Friedel–Crafts alkylation of indoles and pyrroles with 3‐hydroxy‐3‐indolyloxindoles to access two novel types of 3,3‐diaryloxindoles…”
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15
SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy
Published in Neoplasia (New York, N.Y.) (01-10-2022)“…Inhibition of the NEDD8-activating enzyme (NAE), the key E1 enzyme in the neddylation cascade, has been considered an attractive anticancer strategy with the…”
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16
CNN3 in glioma: The prognostic factor and a potential immunotherapeutic target
Published in Medicine (Baltimore) (19-11-2021)“…Gliomas are the most intrinsic type of primary intracranial tumors. The protein encoded by The calponin 3 (CNN3) has been proven to be a member of the calponin…”
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Competing risk model to determine the prognostic factors and treatment strategies for elderly patients with glioblastoma
Published in Scientific reports (29-04-2021)“…The prognostic factors and optimal treatment for the elderly patient with glioblastoma (GBM) were poorly understood. This study extracted 4975 elderly patients…”
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18
Bulk metallic glass composite with good tensile ductility, high strength and large elastic strain limit
Published in Scientific reports (16-06-2014)“…Bulk metallic glasses exhibit high strength and large elastic strain limit but have no tensile ductility. However, bulk metallic glass composites reinforced by…”
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Zearalenone affects the growth of endometriosis via estrogen signaling and inflammatory pathways
Published in Ecotoxicology and environmental safety (01-08-2022)“…Endometriosis is a chronic, inflammatory, estrogen-dependent gynecological disease characterized by the growth of endometrial stromal cells and glands outside…”
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Sensory stimulation to improve arousal in comatose patients after traumatic brain injury: a systematic review of the literature
Published in Neurological sciences (01-09-2020)“…Background No standard rehabilitative treatment for coma arousal after traumatic brain injury (TBI) exists. Based on our clinical experience, we hypothesized…”
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