Search Results - "Song, Paul Y."

Photobiomodulation therapy: management of mucosal necrosis of the oropharynx in previously treated head and neck cancer patients by Epstein, Joel B., Song, Paul Y., Ho, Allen S., Larian, Babak, Asher, Arash, Bensadoun, Rene-Jean

“…Necrosis of the oral mucosa following head and neck cancer radiation therapy presents considerable clinical management challenges. We report three cases of…”
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296 HER2-specific highly scalable CAR NK cell (anti-HER2-CAR SNK02) exhibits a significantly enhanced antitumor activity against HER2-expressing tumors as an off-the-shelf allogeneic immune cell therapy by Rhee, Yong-hee, Chae, Hee-Sung, Kim, Minji, Kang, Seo-Gu, Lee, Joungmin, Kang, Yoon Mi, Jung, Jae Seob, Song, Paul Y, Kim, Yong Man, Gil, Minchan

“…BackgroundAlthough anti-HER2 monoclonal antibodies (e.g., trastuzumab) are currently recognized as effective therapeutics in patients with HER2-overexpressing…”
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Phase I study of SNK01 (autologous non-genetically modified natural killer cells with enhanced cytotoxicity) in refractory metastatic solid tumors by Chawla, Sant P., Kim, Katherine M, Chua, Victoria S., Jafari, Omid, Song, Paul Y.

“…Abstract only e15024 Background: Natural Killer (NK) cells possess the innate ability to detect transformed cancer cells and kill them, thus playing a key role…”
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The combination of CD16A/EGFR innate cell engager, AFM24, with SNK01 autologous natural killer cells in patients with advanced solid tumors by El-Khoueiry, Anthony B., Song, Paul Y., Rubel, Jennifer, Pourang, Dorna Y., Raab, Christa, Hintzen, Gabriele, Emig, Michael, Nava-Parada, Pilar

“…TPS2675 Background: Natural killer (NK) cells are a critical component of the innate immune system involved in the eradication of transformed cells via…”
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Interim analysis of a phase I study of SNK01 (Autologous Nongenetically Modified Natural Killer Cells with Enhanced Cytotoxicity) and avelumab in advanced refractory sarcoma by Chawla, Sant P., Chua-Alcala, Victoria S., Gordon, Erlinda Maria, Kim, Ted T., Feske, William, Gibson, Brenda L., Chang, Paul Y, Robinson, Debra, Song, Paul Y.

“…11517 Background: For patients (pts) with advanced sarcomas in the relapsed/refractory setting, there are very few if any effective salvage treatment options…”
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Use of Expanded Non‐genetically Modified Natural Killer Cells (SNK01) with Enhanced Cytotoxicity in Patients with Advanced Alzheimer’s Disease – Interim Report of a Phase I trial by Gil, Clemente Humberto Zúñiga, Gallo, Blanca Isaura Acosta, Díaz, Rufino Menchaca, Amescua, Cesar Alejandro, Hui, Lucia, Lee, Hank, Mata, Juan, Chang, Paul, Song, Paul Y

“…Background Misfolded protein deposits are known to illicit a cascade of autoreactive neuroinflammation and damage in Alzheimer’s disease (AD). It is clear that…”
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The safety and efficacy of SNK01 (autologous natural killer cells) in combination with cytotoxic chemotherapy after failure of prior tyrosine kinase inhibitor in non-small cell lung cancer: Preclinical mouse model and phase I/IIa clinical study by Choi, Myeong Geun, Son, Gun Woo, Ko, Dae-Hyun, Ji, Wonjun, Rho, Jin Kyung, Lee, Jae Cheol, Kim, Yong Man, Jung, Jae Seob, Song, Paul Y., Yoon, Byeong Gon, Jo, Jong-min, Choi, Mi Young, Choi, Chang-Min

“…9057 Background: It is challenging to choose subsequent treatment option in patients with Osimertinib resistance in epidermal growth factor receptor…”
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A randomized phase I/IIa study to evaluate the safety and efficacy of SNK01 (non-genetically modified autologous natural killer cells with enhanced cytotoxicity) plus pembrolizumab in patients with stage IV non-small cell lung cancer by Kim, Eo Jin, Ko, Dae-Hyun, Ji, Wonjun, Rho, Jin Kyung, Lee, Jae Cheol, Song, Paul Y., Choi, Chang-Min

“…Abstract only 3037 Background: Despite the increased promise of checkpoint inhibitors in the treatment of lung cancer, the overall response rate is…”
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Preliminary analysis of a phase I study of SNK01 (Autologous Non-genetically Modified Natural Killer Cells With Enhanced Cytotoxicity) monotherapy in patients with advanced solid tumors by Chua-Alcala, Victoria S., Chawla, Sant P., Gordon, Erlinda Maria, Kim, Ted T., Sekhon, Simranjit, Feske, William, Hui, Lucia, Gibson, Brenda L., Chang, Paul Y, Robinson, Debra, Song, Paul Y.

“…2644 Background: Natural killer (NK) cells play a key role as the main effector cells toward cancer in innate immunity. Thus, a leading approach is to boost…”
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Phase Ib, international, dose-escalation study to evaluate the safety, pharmacokinetics (PK) and efficacy of ST-617 for the attenuation of oral mucositis (OM) in patients receiving chemoradiation (CRT) for head and neck (H&N) cancer by Osei-Fofie, Daniel, Wetter, Julie, Landers, Greg A., Kraus, Peter Alfred, Sukumaran, Shawgi, Mun, Hui, Stein, Brian N., Bray, Victoria Jane, Framroze, Bomi, Gelfand, Jeffrey, Song, Paul Y., Lategan, Andries, Dimitriu, Mikaela, Sonis, Stephen T.

“…Abstract only 6075 Background: OM is a common, painful, and costly toxicity associated with cytotoxic regimens used to treat H&N cancers, which may result in…”
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Natural killer cells and their activity as a potential biomarker for predicting response to checkpoint inhibitors in non-small cell lung cancer by Song, Paul Y., Cho, Yong-Hee, Choi, Myeong Geun, Kim, Dong Ha, Choi, Yun Jung, Kim, Seon Ye, Sung, Ki Jung, Lee, Jae Cheol, Kim, Sang-Yeob, Rho, Jin Kyung, Choi, Chang-Min

“…Abstract only e15559 Background: Despite the increased promise of checkpoint inhibitors in the treatment of non-small cell lung cancer, the majority of…”
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Use of serial multi-template liquid biopsies in triple negative breast cancer monitoring by Song, Paul Y., Simmons, Jill, Dempsey, Paul W., Klem, Erich, Carter, Chris, Tahvilian, Shahram, Scollick, Brian, Strauss, William

“…Abstract only 1091 Background: Triple negative breast cancer (TNBC) remains the most aggressive subtype of breast cancer in which up to 1/3 of all patients…”
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AFM24 in combination with autologous NK cells (SNK01) in patients with advanced/metastatic epidermal growth factor receptor (EGFR) expressing solid tumors: Initial results from the phase 1 dose-escalation study by El-Khoueiry, Anthony B., Olson, Daniel, Thomas, Jacob Stephen, Pearson, Alexander T., Rubel, Jennifer, Pourang, Dorna Y., Hui, Lucia, Ravenstijn, Paulien, Lutkewitz, Sarah, Hintzen, Gabriele, Emig, Michael, Song, Paul Y., Nava-Parada, Pilar

“…26 Background: AFM24 is a novel tetravalent bispecific IgG1-scFv fusion antibody (scFv-IgAb) binding specifically to EGFR on target cells and CD16A on NK…”
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Effect of BPM 31510 on survival outcomes when used in combination with gemcitabine in a preclinical model of pancreatic cancer by Jimenez, Joaquin J., Mauro, Lucia M, Akmaev, Viacheslav R, McCook, John, Du, Min, Luan, Shen, Song, Paul Y., Sarangarajan, Rangaprasad, Narain, Niven R

“…Abstract only e14593 Background: BPM 31510 is a novel small molecule that targets the metabolic machinery of the cancer microenvironment to create a hallmark…”
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Phase I study of BPM 31510 in advanced solid tumors: Updated analysis of a novel treatment with promising activity by Hendifar, Andrew Eugene, Chawla, Sant P., Quon, Doris, Chua, Victoria S, Fernandez, Lita, Nagre, Sandeep, Okunnu, Marita, Chmielowski, Bartosz, Singh, Arun S., Akmaev, Slava, Chatman, David, McCook, John, Luan, Shen, Sarangarajan, Rangaprasad, Song, Paul Y., Narain, Niven R

“…Abstract only 3015 Background: BPM 31510 is a novel small molecule that targets the metabolic machinery of the cancer microenvironment to reverse the aerobic…”
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Abstract 3735: Increased efficacy with use of combination therapy of API 31510 and gemcitabine in the treatment of pancreatic cancer by Narain, Niven R., Sarangarajan, Rangaprasad, Ouro-Djobo, Rakib, Bourdelais, Justin J., Grund, Eric, Vishnudas, Vivek, Mauro, Lucia M., Lens, Assuan, Yunis, Adel, Agarwal, Shuili, Song, Paul Y., McCook, John P., Jimenez, Joaquin J.

“…Abstract Pancreatic Carcinoma is one of the deadliest types of cancers and certainly one that is most clinically difficult to manage given that most diagnoses…”
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A comparison of four patient immobilization devices in the treatment of prostate cancer patients with three dimensional conformal radiotherapy by Song, P Y, Washington, M, Vaida, F, Hamilton, R, Spelbring, D, Wyman, B, Harrison, J, Chen, G T

“…To determine the variability of patient positioning during three-dimensional conformal radiotherapy (3D-CRT) for prostate cancer treated with no immobilization…”
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A method of analyzing rectal surface area irradiated and rectal complications in prostate conformal radiotherapy by Lu, Y, Song, P Y, Li, S D, Spelbring, D R, Vijayakumar, S, Haraf, D J, Chen, G T

“…To develop a method of analyzing rectal surface area irradiated and rectal complications in prostate conformal radiotherapy. Dose-surface histograms of the…”
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Medulloblastoma: differences in adults and children--regarding Frost et al., IJROBP 32:951-957; 1995 and Prados et al., IJROBP 32:1145-1152; 1995 by Haie-Meder, C, Song, P Y

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Liquid biopsy testing in monitoring TNBC by Song, Paul Y

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