Search Results - "Song, Linsheng"

Ammonia exposure induces oxidative stress, endoplasmic reticulum stress and apoptosis in hepatopancreas of pacific white shrimp (Litopenaeus vannamei) by Liang, Zhongxiu, Liu, Rui, Zhao, Depeng, Wang, Lingling, Sun, Mingzhe, Wang, Mengqiang, Song, Linsheng

“…Ammonia is one of major environmental pollutants in the aquatic system that poses a great threat to the survival of shrimp. In the present study, the mRNA…”
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Pathogen-Derived Carbohydrate Recognition in Molluscs Immune Defense by Wang, Weilin, Song, Xiaorui, Wang, Lingling, Song, Linsheng

“…Self-nonself discrimination is a common theme for all of the organisms in different evolutionary branches, which is also the most fundamental step for host…”
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The Establishment of Complement System Is from Gene Duplication and Domain Shuffling by Sun, Jiejie, Liu, Chang, Wang, Lingling, Song, Linsheng

“…The mammalian complement system constitutes a highly sophisticated body defense machinery. The evolutionary origin of the complement system can be traced to…”
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Recent Advances of Shell Matrix Proteins and Cellular Orchestration in Marine Molluscan Shell Biomineralization by Song, Xiaorui, Liu, Zhaoqun, Wang, Lingling, Song, Linsheng

“…Biomineralization refers to the dynamic physiological processes whereby living organisms elaborate mineralized tissues. The existence of extremely abundant…”
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The Neuroendocrine-Immune Regulation in Response to Environmental Stress in Marine Bivalves by Liu, Zhaoqun, Li, Meijia, Yi, Qilin, Wang, Lingling, Song, Linsheng

“…Marine bivalves, which include many species worldwide, from intertidal zones to hydrothermal vents and cold seeps, are important components of the ecosystem…”
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The granulocytes are the main immunocompetent hemocytes in Crassostrea gigas by Wang, Weilin, Li, Meijia, Wang, Lingling, Chen, Hao, Liu, Zhaoqun, Jia, Zhihao, Qiu, Limei, Song, Linsheng

“…Hemocytes comprise diverse cell types with morphological and functional heterogeneity and play indispensable roles in immunological homeostasis of…”
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The various components implied the diversified Toll-like receptor (TLR) signaling pathway in mollusk Chlamys farreri by Wang, Mengqiang, Wang, Lingling, Jia, Zhihao, Yi, Qilin, Song, Linsheng

“…Toll-like receptor (TLR) signaling pathway, composed of various components, plays pivotal roles in host innate immune defense mechanism. In the present study,…”
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Metabolomic and transcriptomic profiling reveals the alteration of energy metabolism in oyster larvae during initial shell formation and under experimental ocean acidification by Liu, Zhaoqun, Zhang, Yukun, Zhou, Zhi, Zong, Yanan, Zheng, Yan, Liu, Chang, Kong, Ning, Gao, Qiang, Wang, Lingling, Song, Linsheng

“…Marine bivalves secrete calcified shells to protect their soft bodies from predation and damages, which is of great importance for their survival, and for the…”
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The cGAS/STING–TBK1–IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster by Qiao, Xue, Zong, Yanan, Liu, Zhaoqun, Wu, Zhaojun, Li, Yuanmei, Wang, Lingling, Song, Linsheng

“…Interferon (IFN) system is considered as the first defense line against viral infection, and it has been extensively studied in vertebrates from fish to…”
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The Modification of H3K4me3 Enhanced the Expression of CgTLR3 in Hemocytes to Increase CgIL17-1 Production in the Immune Priming of Crassostrea gigas by Lian, Xingye, Li, Yinan, Wang, Weilin, Zuo, Jiajun, Yu, Tianqi, Wang, Lingling, Song, Linsheng

“…Increasing evidence confirms that histone modification plays a critical role in preserving long-term immunological memory. Immune priming is a novel form of…”
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The glutaminase (CgGLS-1) mediates anti-bacterial immunity by prompting cytokine synthesis and hemocyte apoptosis in Pacific oyster Crassostrea gigas by Liang, Yage, Li, Meijia, Liu, Zhaoqun, Li, Yuanmei, Wang, Lingling, Song, Linsheng

“…Glutaminase, an amidohydrolase enzyme that hydrolyzes glutamine to glutamate, plays crucial roles in various immunomodulatory processes such as cell apoptosis,…”
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The Roles of Two miRNAs in Regulating the Immune Response of Sea Cucumber by Zhang, Pengjuan, Li, Chenghua, Zhang, Ran, Zhang, Weiwei, Jin, Chunhua, Wang, Lingling, Song, Linsheng

“…MicroRNAs (miRNAs) have emerged as key regulators in many pathological processes by suppressing the transcriptional and post-transcriptional expression of…”
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C-type lectin in Chlamys farreri (CfLec-1) mediating immune recognition and opsonization by Yang, Jialong, Wang, Lingling, Zhang, Huan, Qiu, Limei, Wang, Hao, Song, Linsheng

“…C-type lectins are a superfamily of Ca(2+) dependent carbohydrate-recognition proteins that play significant diverse roles in nonself-recognition and clearance…”
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Chromosome-level genome assembly of the deep-sea snail Phymorhynchus buccinoides provides insights into the adaptation to the cold seep habitat by Liu, Zhaoqun, Huang, Yuting, Chen, Hao, Liu, Chang, Wang, Minxiao, Bian, Chao, Wang, Lingling, Song, Linsheng

“…Abstract Background The deep-sea snail Phymorhynchus buccinoides belongs to the genus Phymorhynchus (Neogastropoda: Raphitomidae), and it is a dominant specie…”
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An integrin from oyster Crassostrea gigas mediates the phagocytosis toward Vibrio splendidus through LPS binding activity by Jia, Zhihao, Zhang, Tao, Jiang, Shuai, Wang, Mengqiang, Cheng, Qi, Sun, Mingzhe, Wang, Lingling, Song, Linsheng

“…Integrins are a family of cell adhesion molecules which play important roles in the regulation of cell adhesion, migration, proliferation, apoptosis and…”
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An Ancient BCR-like Signaling Promotes ICP Production and Hemocyte Phagocytosis in Oyster by Sun, Jiejie, Wang, Lingling, Yang, Chuanyan, Song, Linsheng

“…BCR/TCR-based adaptive immune systems arise in the jawed vertebrates, and B cell receptors (BCRs) play an important role in the clonal selection of B cells and…”
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CfLec-3 from scallop: an entrance to non-self recognition mechanism of invertebrate C-type lectin by Yang, Jialong, Huang, Mengmeng, Zhang, Huan, Wang, Lingling, Wang, Hao, Wang, Leilei, Qiu, Limei, Song, Linsheng

“…A C-type lectin (CfLec-3) from Chlamys farreri with three carbohydrate-recognition domains (CRDs) was selected to dissect the possible mechanisms of PAMP…”
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The identification and characteristics of immune-related microRNAs in haemocytes of oyster Crassostrea gigas by Zhou, Zhi, Wang, Lingling, Song, Linsheng, Liu, Rui, Zhang, Huan, Huang, Mengmeng, Chen, Hao

“…MicroRNAs (miRNAs) represent a class of small ncRNAs that repress gene expression on the post-transcriptional level by the degradation or translation…”
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Histone lysine-specific demethylase 1 regulates the proliferation of hemocytes in the oyster Crassostrea gigas by Gu, Xiaoyu, Qiao, Xue, Yu, Simiao, Song, Xiaorui, Wang, Lingling, Song, Linsheng

“…Lysine-specific demethylase 1 (LSD1) is an essential epigenetic regulator of hematopoietic differentiation, which can specifically mono-methylate H3K4…”
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The broad pattern recognition spectrum of the Toll-like receptor in mollusk Zhikong scallop Chlamys farreri by Wang, Mengqiang, Wang, Lingling, Guo, Ying, Sun, Rui, Yue, Feng, Yi, Qilin, Song, Linsheng

“…•CfTLR was primitive mollusk TLR.•CfTLR developed a hybrid function in pattern recognition with broader ligands.•The mosaic capability of CfTLR might be due to…”
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