Search Results - "Song, Libing"
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Oncogenic miR-210-3p promotes prostate cancer cell EMT and bone metastasis via NF-κB signaling pathway
Published in Molecular cancer (10-07-2017)“…The primary issue arising from prostate cancer (PCa) is its high prevalence to metastasize to bone, which severely affects the quality of life and survival…”
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2
cMyc-mediated activation of serine biosynthesis pathway is critical for cancer progression under nutrient deprivation conditions
Published in Cell research (01-04-2015)“…Cancer cells are known to undergo metabolic reprogramming to sustain survival and rapid proliferation, however, it remains to be fully elucidated how oncogenic…”
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3
Nicotine-mediated OTUD3 downregulation inhibits VEGF-C mRNA decay to promote lymphatic metastasis of human esophageal cancer
Published in Nature communications (01-12-2021)“…Nicotine addiction and the occurrence of lymph node spread are two major significant factors associated with esophageal cancer’s poor prognosis; however,…”
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4
Wnt5a induces and maintains prostate cancer cells dormancy in bone
Published in The Journal of experimental medicine (04-02-2019)“…In a substantial fraction of prostate cancer (PCa) patients, bone metastasis appears after years or even decades of latency. Canonical Wnt/β-catenin signaling…”
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5
Hepatocellular carcinoma redirects to ketolysis for progression under nutrition deprivation stress
Published in Cell research (01-10-2016)“…Cancer cells are known for their capacity to rewire metabolic pathways to support survival and proliferation under various stress conditions. Ketone bodies,…”
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6
USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer
Published in Nature communications (26-09-2022)“…Indoleamine 2,3 dioxygenase 1 (IDO1) is an attractive target for cancer immunotherapy. However, IDO1 inhibitors have shown disappointing therapeutic efficacy…”
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7
Circular RNA circIKBKB promotes breast cancer bone metastasis through sustaining NF-κB/bone remodeling factors signaling
Published in Molecular cancer (29-07-2021)“…Breast cancer (BC) has a marked tendency to spread to the bone, resulting in significant skeletal complications and mortality. Recently, circular RNAs…”
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8
HIF-1-Mediated Suppression of Acyl-CoA Dehydrogenases and Fatty Acid Oxidation Is Critical for Cancer Progression
Published in Cell reports (Cambridge) (25-09-2014)“…Hypoxia-inducible factor 1 (HIF-1) mediates a metabolic switch that blocks the conversion of pyruvate to acetyl-CoA in cancer cells. Here, we report that…”
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9
Epigenetic Induction of Mitochondrial Fission Is Required for Maintenance of Liver Cancer-Initiating Cells
Published in Cancer research (Chicago, Ill.) (15-07-2021)“…Mitochondrial dynamics play vital roles in the tumorigenicity and malignancy of various types of cancers by promoting the tumor-initiating potential of cancer…”
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10
Nucleolar and spindle associated protein 1 promotes metastasis of cervical carcinoma cells by activating Wnt/β-catenin signaling
Published in Journal of experimental & clinical cancer research (24-01-2019)“…The primary obstacle to treat cervical cancer is its high prevalence of metastasis, which severely affects patients' quality of life and survival time…”
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11
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1
Published in Nature communications (10-10-2014)“…Aberrant expression of Lin28 and let-7 has been observed in many human malignancies. However, its functions and underlying mechanisms remain largely elusive…”
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12
Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis
Published in The Journal of clinical investigation (01-06-2015)“…Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation. GLS is being explored as a…”
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13
Sphingosine Kinase-1 Enhances Resistance to Apoptosis through Activation of PI3K/Akt/NF-κB Pathway in Human Non-Small Cell Lung Cancer
Published in Clinical cancer research (01-04-2011)“…The present study was to examine the effect of sphingosine kinase-1 (SPHK1) on chemotherapeutics-induced apoptosis in non-small cell lung cancer (NSCLC) cells,…”
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14
Overexpression of GOLPH3 Promotes Proliferation and Tumorigenicity in Breast Cancer via Suppression of the FOXO1 Transcription Factor
Published in Clinical cancer research (01-08-2012)“…Golgi phosphoprotein 3 (GOLPH3) has been reported to be involved in various biologic processes. The clinical significance and biologic role of GOLPH3 in breast…”
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15
Thymosin beta 10 is a key regulator of tumorigenesis and metastasis and a novel serum marker in breast cancer
Published in Breast cancer research : BCR (08-02-2017)“…Thymosin beta 10 (TMSB10) has been demonstrated to be involved in the malignant process of many cancers. The purpose of this study was to determine the…”
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16
N-cadherin promotes epithelial-mesenchymal transition and cancer stem cell-like traits via ErbB signaling in prostate cancer cells
Published in International journal of oncology (01-02-2016)“…N-cadherin has been reported to be upregulated and associated with metastasis and poor prognosis in prostate cancer patients, however the underlying mechanism…”
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17
Unregulated miR-96 induces cell proliferation in human breast cancer by downregulating transcriptional factor FOXO3a
Published in PloS one (23-12-2010)“…FOXO transcription factors are key tumor suppressors in mammalian cells. Until now, suppression of FOXOs in cancer cells was thought to be mainly due to…”
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B3GNT3 Expression Is a Novel Marker Correlated with Pelvic Lymph Node Metastasis and Poor Clinical Outcome in Early-Stage Cervical Cancer
Published in PloS one (28-12-2015)“…The β1,3-N-acetylglucosaminyltransferase-3 gene (B3GNT3) encodes a member of the B3GNT family that functions as the backbone structure of dimeric sialyl-Lewis…”
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19
AKIP1 promotes early recurrence of hepatocellular carcinoma through activating the Wnt/β-catenin/CBP signaling pathway
Published in Oncogene (04-07-2019)“…The early recurrence of hepatocellular carcinoma (HCC) is the main obstacle for long-term survival of patients. Wnt/β-catenin signaling has been involved in…”
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Zinc finger protein 367 promotes metastasis by inhibiting the Hippo pathway in breast cancer
Published in Oncogene (01-03-2020)“…Circulating tumor cells (CTC) disseminating is an important cause of distant metastasis. However, the mechanism involved in increasing the numbers of CTCs in…”
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