Search Results - "Song, Jingrui"
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The first mitochondrial genomes for Pyralinae (Pyralidae) and Glaphyriinae (Crambidae), with phylogenetic implications of Pyraloidea
Published in PloS one (27-03-2018)“…In the present study, we report five complete and one nearly complete mitochondrial genomes of the Pyraloidea including the first representatives from the…”
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Design, Synthesis, and Anti-Leukemic Evaluation of a Series of Dianilinopyrimidines by Regulating the Ras/Raf/MEK/ERK and STAT3/c-Myc Pathways
Published in Molecules (Basel, Switzerland) (01-04-2024)“…Although the long-term survival rate for leukemia has made significant progress over the years with the development of chemotherapeutics, patients still suffer…”
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Calothrixin B derivatives induce apoptosis and cell cycle arrest on HEL cells through the ERK/Ras/Raf/MEK pathway
Published in Biomedicine & pharmacotherapy (01-02-2024)“…Acute erythroleukemia (AEL) is acute myeloid leukemia characterized by malignant erythroid proliferation. AEL has a low survival rate, which has seriously…”
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L20, a Calothrixin B analog, induces intrinsic apoptosis on HEL cells through ROS/γ-H2AX/p38 MAPK pathway
Published in Biomedicine & pharmacotherapy (01-05-2021)“…Erythroleukemia is a malignant disease in the blood system. Quinones consists of a class of antitumor agents. Calothrixin B is a carbazole-1,4-quinone alkaloid…”
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Garmultin-A Incites Apoptosis in CB3 Cells Through miR-17-5p by Attenuating Poly (ADP-Ribose) Polymerase-1
Published in Dose-response (01-10-2022)“…Background Leukemia accounts for a large number of deaths, worldwide, every year. Treating this ailment is always a challenging job. Recently, oncogenic miRNA…”
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A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model
Published in Biomedicine & pharmacotherapy (01-09-2021)“…Leukemia is responsible for a reason of death, globally. Even though there are several treatment regimens available in the clinics against this disease, a…”
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BW18, a C-21 steroidal glycoside, exerts an excellent anti-leukemia activity through inducing S phase cell cycle arrest and apoptosis via MAPK pathway in K562 cells
Published in Biomedicine & pharmacotherapy (01-04-2019)“…[Display omitted] •BW18 inhibits cell viability and proliferation of K562 cells.•BW18 induces S phase cell cycle arrest and apoptosis of K562 cells.•BW18…”
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TMJ-105, an extract of Carpesium cernuum, induced G2/M phase arrest and apoptosis via the JAK2/STAT3 axis and MAPKs signaling pathway in leukemia HEL cells
Published in Heliyon (30-07-2024)“…Leukemia is a malignant tumor of the hematologic system. Studies have shown that cernuumolide J (TMJ-105), an extract of Carpesium cernuum, has anti-cancer…”
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A natural small molecule induces megakaryocytic differentiation and suppresses leukemogenesis through activation of PKCδ/ERK1/2 signaling pathway in erythroleukemia cells
Published in Biomedicine & pharmacotherapy (01-10-2019)“…[Display omitted] •KCR inhibits cell viability of erythroleukemia cells.•KCR promotes cell apoptosis of erythroleukemia cells.•KCR induces G2/M phase cell…”
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Design, Synthesis, and Antileukemic Evaluation of a Novel Mikanolide Derivative Through the Ras/Raf/MEK/ERK Pathway
Published in Frontiers in pharmacology (20-05-2022)“…Chronic myeloid leukemia (CML) accounts for a major cause of death in adult leukemia patients due to mutations or other reasons for dysfunction in the ABL…”
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E3 Ligase FBXW7 Facilitates Mycobacterium Immune Evasion by Modulating TNF-α Expression
Published in Frontiers in cellular and infection microbiology (16-05-2022)“…Tumor necrosis factor alpha (TNF-α) is a crucial factor in the control of ( ) infection. Pathogenic mycobacteria can inhibit and/or regulate host cell TNF-α…”
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A New Indole Derivative, LWX-473, Overcomes Glucocorticoid Resistance in Jurkat Cells by Activating Mediators of Apoptosis
Published in Frontiers in bioscience (Landmark. Print) (23-04-2024)“…Glucocorticoids (GCs) are commonly used as the primary chemotherapy for lymphoid malignancies, including acute lymphoblastic leukemia (ALL). However, the…”
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13
Pathogenic mycobacterium upregulates cholesterol 25-hydroxylase to promote granuloma development via foam cell formation
Published in iScience (15-03-2024)“…Pathogenic mycobacteria orchestrate the complex cell populations known as granuloma that is the hallmark of tuberculosis. Foam cells, a lipid-rich cell-type,…”
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14
The first mitochondrial genomes for Pyralinae
Published in PloS one (27-03-2018)“…In the present study, we report five complete and one nearly complete mitochondrial genomes of the Pyraloidea including the first representatives from the…”
Get full text
Journal Article -
15
The first mitochondrial genomes for Pyralinae , with phylogenetic implications of Pyraloidea
Published in PloS one (27-03-2018)“…In the present study, we report five complete and one nearly complete mitochondrial genomes of the Pyraloidea including the first representatives from the…”
Get full text
Journal Article -
16
IQGAP1 domesticates macrophages to favor mycobacteria survival via modulating NF-κB signal and augmenting VEGF secretion
Published in International immunopharmacology (10-09-2024)“…•IQGAP1 was induced in macrophages via a mycobacterial virulence determinant-dependent manner during M.marinum infection.•It’s the first report to demonstrate…”
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17
The Flavagline Compound 1
Published in Drug design, development and therapy (31-08-2022)“…Purpose: Chronic myelogenous leukemia (CML) is a hematological malignancy with increased proliferation of cells of the myeloid series. This can disrupt normal…”
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The Flavagline Compound 1--Rocaglaol Induces Apoptosis in K562 Cells by Regulating the PI3K/Akt/mTOR, JAK2/STAT3, and MAPK Pathways
Published in Drug design, development and therapy (31-08-2022)“…Purpose: Chronic myelogenous leukemia (CML) is a hematological malignancy with increased proliferation of cells of the myeloid series. This can disrupt normal…”
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A racemosin B derivative, C25, suppresses breast cancer growth via lysosomal membrane permeabilization and inhibition of autophagic flux
Published in Biochemical pharmacology (01-07-2022)“…[Display omitted] Breast cancer is the most common malignancy among women worldwide. As conventional therapies are only partially successful in eradicating…”
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Incaspitolide A extracted from Carpesium cernuum induces apoptosis in vitro via the PI3K/AKT pathway in benign prostatic hyperplasia
Published in Bioscience reports (25-06-2021)“…Benign prostatic hyperplasia (BPH) is a common disease that occurs mainly in older men. The pathogenesis of BPH is complex and patients face a prolonged…”
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