Search Results - "Song, Erqun"

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics by Zhu, Guizhi, Zheng, Jing, Song, Erqun, Donovan, Michael, Zhang, Kejing, Liu, Chen, Tan, Weihong

“…Nanotechnology has allowed the construction of various nanostructures for applications, including biomedicine. However, a simple target-specific, economical,…”
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“Iron free” zinc oxide nanoparticles with ion-leaking properties disrupt intracellular ROS and iron homeostasis to induce ferroptosis by Zhang, Changping, Liu, Zixuan, Zhang, Yuhao, Ma, Liang, Song, Erqun, Song, Yang

“…Exposure to nanomaterials (NMs) is an emerging threat to human health, and the understanding of their intracellular behavior and related toxic effects is…”
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Co-administration of lipopolysaccharide and d-galactosamine induces genotoxicity in mouse liver by Dong, Wenjing, Song, Erqun, Song, Yang

“…The acute liver injury (ALI) and hepatic fibrosis caused by the co-treatment of lipopolysaccharide (LPS)/ d -galactosamine (D-GalN) have been extensively…”
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Dual Recognition Strategy for Specific and Sensitive Detection of Bacteria Using Aptamer-Coated Magnetic Beads and Antibiotic-Capped Gold Nanoclusters by Cheng, Dan, Yu, Mengqun, Fu, Fei, Han, Weiye, Li, Gan, Xie, Jianping, Song, Yang, Swihart, Mark T, Song, Erqun

“…Food poisoning and infectious diseases caused by pathogenic bacteria such as Staphylococcus aureus (SA) are serious public health concerns. A method of…”
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Polybrominated diphenyl ether quinone exposure leads to ROS-driven lysosomal damage, mitochondrial dysfunction and NLRP3 inflammasome activation by Yang, Bingwei, Wang, Yuting, Fang, Changyu, Song, Erqun, Song, Yang

“…Polybrominated diphenyl ethers (PBDEs) are aromatic compounds that containing bromine atoms, which possess high efficiency, good thermal stability. However,…”
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Aptamer-quantum dots and teicoplanin-gold nanoparticles constructed FRET sensor for sensitive detection of Staphylococcus aureus by Tao, Xiaoqi, Liao, Ziyi, Zhang, Yaqing, Fu, Fei, Hao, Mengqi, Song, Yang, Song, Erqun

“…In the presence of target S. aureus, the aptamers and teicoplanin bound to S. aureus simultaneously, making the energy donor (aptamer-QDs) and acceptor…”
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Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression by Zhang, Pan, He, Dan, Song, Erqun, Jiang, Mingdong, Song, Yang

“…The current study aimed to identify the radiosensitizing effect of celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, in combination with radiotherapy…”
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Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation by Liu, Zixuan, Lv, Xuying, Xu, Lei, Liu, Xuting, Zhu, Xiangyu, Song, Erqun, Song, Yang

“…Abstract Background With the development of zinc oxide nanoparticles (ZnO NPs) in the field of nanotechnology, their toxicological effects are attracting…”
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A graphene oxide-based FRET sensor for rapid and sensitive detection of matrix metalloproteinase 2 in human serum sample by Song, Erqun, Cheng, Dan, Song, Yang, Jiang, Mingdong, Yu, Jifei, Wang, Yunyun

“…Graphene oxide (GO) has been widely used to develop fluorescence resonance energy transfer (FRET) biosensors for tumor markers (e.g., matrix…”
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Rapid detection of pathogenic bacteria based on a universal dual-recognition FRET sensing system constructed with aptamer-quantum dots and lectin-gold nanoparticles by Zhang, Yaqing, Liu, Yan, Yang, Yun, Li, Linyao, Tao, Xiaoqi, Song, Erqun

“…The threat to public health from bacterial infections has led to an urgent need to develop simpler, faster and more reliable bacterial detection methods. In…”
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Activating Transcription Factor 4 (ATF4)-ATF3-C/EBP Homologous Protein (CHOP) Cascade Shows an Essential Role in the ER Stress-Induced Sensitization of Tetrachlorobenzoquinone-Challenged PC12 Cells to ROS-Mediated Apoptosis via Death Receptor 5 (DR5) Signaling by Liu, Zixuan, Shi, Qiong, Song, Xiufang, Wang, Yuxin, Wang, Yawen, Song, Erqun, Song, Yang

“…Tetrachlorobenzoquinone (TCBQ) is a downstream metabolite of pentachlorophenol (PCP). Previously, we demonstrated that TCBQ caused cytotoxicity due to…”
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Bazhen decoction protects against acetaminophen induced acute liver injury by inhibiting oxidative stress, inflammation and apoptosis in mice by Song, Erqun, Fu, Juanli, Xia, Xiaomin, Su, Chuanyang, Song, Yang

“…Bazhen decoction is a widely used traditional Chinese medicinal decoction, but the scientific validation of its therapeutic potential is lacking. The objective…”
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A Spherical Nucleic Acid Platform Based on Self-Assembled DNA Biopolymer for High-Performance Cancer Therapy by Zheng, Jing, Zhu, Guizhi, Li, Yinhui, Li, Chunmei, You, Mingxu, Chen, Tao, Song, Erqun, Yang, Ronghua, Tan, Weihong

“…Based on their enhanced cellular uptake, stability, biocompatibility, and versatile surface functionalization, spherical nucleic acids (SNAs) have become a…”
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MicroRNA-33b, upregulated by EF24, a curcumin analog, suppresses the epithelial-to-mesenchymal transition (EMT) and migratory potential of melanoma cells by targeting HMGA2 by Zhang, Pu, Bai, Huiyuan, Liu, Gentao, Wang, Heyong, Chen, Feng, Zhang, Baoshun, Zeng, Panying, Wu, Chengxiang, Peng, Cong, Huang, Changjin, Song, Yang, Song, Erqun

“…•EF24 suppressed melanoma migration and EMT.•EF24 increased miR-33b expression and subsequently inhibited HMGA2 expression.•EF24 suppressed melanoma EMT by…”
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Selenium deficiency sensitizes the skin for UVB-induced oxidative damage and inflammation which involved the activation of p38 MAPK signaling by Zhu, Xiaokang, Jiang, Mingdong, Song, Erqun, Jiang, Xiaoji, Song, Yang

“…•Selenium deficiency sensitizes UVB-induced oxidative damage.•Selenium deficiency sensitizes UVB-induced loss of antioxidant enzyme activities.•Selenium…”
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Polychlorinated biphenyl quinone induces hepatocytes iron overload through up-regulating hepcidin expression by Liu, Jing, Tan, Ya, Yang, Bingwei, Wu, Yunjie, Fan, Bailing, Zhu, Sixi, Song, Erqun, Song, Yang

“…•PCB29-pQ-induced lipid peroxidation and iron overload.•PCB29-pQ-induced iron overload is related to ROS.•PCB29-pQ stimulated hepcidin expression through Nrf2…”
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Hepatotoxicity and genotoxicity of patulin in mice, and its modulation by green tea polyphenols administration by Song, Erqun, Xia, Xiaomin, Su, Chuanyang, Dong, Wenjing, Xian, Yaping, Wang, Wei, Song, Yang

“…•PAT increased serum ALT and AST activities significantly.•PAT increased TBARS and ROS level, decreased GSH level.•PAT increased micronucleus and chromosomal…”
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Synergistic hydroxyl radical formation, system XC- inhibition and heat shock protein crosslinking tango in ferrotherapy: A prove-of-concept study of “sword and shield” theory by Xie, Li, Chen, Wenjie, Chen, Qifang, Jiang, Yang, Song, Erqun, Zhu, Xiaokang, Song, Yang

“…Ferroptosis provide new insights into designing nanomedicines for enhanced cancer therapy; however, its antitumor efficacy is relatively low, mainly due to…”
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Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k by Shi, Qiong, Song, Xiufang, Liu, Zixuan, Wang, Yawen, Wang, Yuxin, Fu, Juanli, Su, Chuanyang, Xia, Xiaomin, Song, Erqun, Song, Yang

“…Autophagy is a “self-eating” destructive process that eliminates damaged organelles to maintain cellular homeostasis. Polychlorinated biphenyls (PCBs) are one…”
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Neohesperidin Dihydrochalcone versus CCl4‑Induced Hepatic Injury through Different Mechanisms: The Implication of Free Radical Scavenging and Nrf2 Activation by Su, Chuanyang, Xia, Xiaomin, Shi, Qiong, Song, Xiufang, Fu, Juanli, Xiao, Congxue, Chen, Hongjun, Lu, Bin, Sun, Zhiyin, Wu, Shanmei, Yang, Siyu, Li, Xuegang, Ye, Xiaoli, Song, Erqun, Song, Yang

“…Neohesperidin dihydrochalcone (NHDC), a sweetener derived from citrus, belongs to the family of bycyclic flavonoids dihydrochalcones. NHDC has been reported to…”
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