Search Results - "Song, Cheng J"

User-friendly microfluidic system reveals native-like morphological and transcriptomic phenotypes induced by shear stress in proximal tubule epithelium by Khalil, Natalie N., Petersen, Andrew P., Song, Cheng J., Chen, Yibu, Takamoto, Kaelyn, Kellogg, Austin C., Chen, Elaine Zhelan, McMahon, Andrew P., McCain, Megan L.

“…Drug-induced nephrotoxicity is a leading cause of drug attrition, partly due to the limited relevance of pre-clinical models of the proximal tubule. Culturing…”
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A kidney resident macrophage subset is a candidate biomarker for renal cystic disease in preclinical models by Li, Zhang, Zimmerman, Kurt A, Cherakara, Sreelakshmi, Chumley, Phillip H, Collawn, James F, Wang, Jun, Haycraft, Courtney J, Song, Cheng J, Chacana, Teresa, Andersen, Reagan S, Croyle, Mandy J, Aloria, Ernald J, Hombal, Raksha P, Thomas, Isis N, Chweih, Hanan, Simanyi, Kristin L, George, James F, Parant, John M, Mrug, Michal, Yoder, Bradley K

“…Although renal macrophages have been shown to contribute to cyst development in polycystic kidney disease (PKD) animal models, it remains unclear whether there…”
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Cx3cr1 controls kidney resident macrophage heterogeneity by Yashchenko, Alex, Bland, Sarah J, Song, Cheng J, Ahmed, Ummey Khalecha Bintha, Sharp, Rachel, Darby, Isabella G, Cordova, Audrey M, Smith, Morgan E, Lever, Jeremie M, Li, Zhang, Aloria, Ernald J, Khan, Shuja, Maryam, Bibi, Liu, Shanrun, Crowley, Michael R, Jones, Kenneth L, Zenewicz, Lauren A, George, James F, Mrug, Michal, Crossman, David K, Hopp, Katharina, Stavrakis, Stavros, Humphrey, Mary B, Ginhoux, Florent, Zimmerman, Kurt A

“…Kidney macrophages are comprised of both monocyte-derived and tissue resident populations; however, the heterogeneity of kidney macrophages and factors that…”
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Tissue-Resident Macrophages Promote Renal Cystic Disease by Zimmerman, Kurt A, Song, Cheng J, Li, Zhang, Lever, Jeremie M, Crossman, David K, Rains, Addison, Aloria, Ernald J, Gonzalez, Nancy M, Bassler, John R, Zhou, Juling, Crowley, Michael R, Revell, Dustin Z, Yan, Zhaoqi, Shan, Dan, Benveniste, Etty N, George, James F, Mrug, Michal, Yoder, Bradley K

“…Mutations affecting cilia proteins have an established role in renal cyst formation. In mice, the rate of cystogenesis is influenced by the age at which cilia…”
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Early infiltrating macrophage subtype correlates with late-stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease by Zimmerman, Kurt A., Song, Cheng J., Aloria, Ernald J.G., Li, Zhang, Zhou, Juling, Bland, Sarah J., Yashchenko, Alex, Crossman, David K., Mrug, Michal, Yoder, Bradley K.

“…Hepatorenal fibrocystic disease (HRFCD) is a genetically inherited disorder related to primary cilia dysfunction in which patients display varying levels of…”
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A Comprehensive Immune Cell Atlas of Cystic Kidney Disease Reveals the Involvement of Adaptive Immune Cells in Injury-Mediated Cyst Progression in Mice by Song, Cheng J, Li, Zhang, Ahmed, Ummey Khalecha Bintha, Bland, Sarah J, Yashchenko, Alex, Liu, Shanrun, Aloria, Ernald J, Lever, Jeremie M, Gonzalez, Nancy M, Bickel, Marisa A, Giles, Cory B, Georgescu, Constantin, Wren, Jonathan D, Lang, Mark L, Benveniste, Etty N, Harrington, Laurie E, Tsiokas, Leo, George, James F, Jones, Kenneth L, Crossman, David K, Agarwal, Anupam, Mrug, Michal, Yoder, Bradley K, Hopp, Katharina, Zimmerman, Kurt A

“…Inducible disruption of cilia-related genes in adult mice results in slowly progressive cystic disease, which can be greatly accelerated by renal injury. To…”
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Ly6chi Infiltrating Macrophages Promote Cyst Progression in Injured Conditional Ift88 Mice by Aloria, Ernald Jules G., Song, Cheng J., Li, Zhang, Croyle, Mandy J., Mrug, Michal, Zimmerman, Kurt A., Yoder, Bradley K.

“…Key Points Ly6c hi infiltrating macrophage numbers are increased in injured, conditional Ift88 mice, compared with controls. Loss of Ly6c hi infiltrating…”
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Ly6c hi Infiltrating Macrophages Promote Cyst Progression in Injured Conditional Ift88 Mice by Aloria, Ernald Jules G, Song, Cheng J, Li, Zhang, Croyle, Mandy J, Mrug, Michal, Zimmerman, Kurt A, Yoder, Bradley K

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Early infiltrating macrophage subtype correlates with late-stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease by Zimmerman, Kurt A, Song, Cheng J, Aloria, Ernald J G, Li, Zhang, Zhou, Juling, Bland, Sarah J, Yashchenko, Alex, Crossman, David K, Mrug, Michal, Yoder, Bradley K

“…Hepatorenal fibrocystic disease (HRFCD) is a genetically inherited disorder related to primary cilia dysfunction in which patients display varying levels of…”
Get full text