Search Results - "Sonawat, Haripalsingh M."

Early Perturbations in Red Blood Cells in Response to Murine Malarial Parasite Infection: Proof-of-Concept 1H NMR Metabolomic Study by Sengupta, Arjun, Ghosh, Soumita, Sharma, Shobhona, Sonawat, Haripalsingh

“…Background: The major focus of metabolomics research has been confined to the readily available biofluids—urine and blood serum. However, red blood cells…”
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Early Perturbations in Glucose Utilization in Malaria-Infected Murine Erythrocytes, Liver and Brain Observed by Metabolomics by Sengupta, Arjun, Ghosh, Soumita, Sharma, Shobhona, Sonawat, Haripalsingh M.

“…Investigation of glucose utilization during an infection is central to the study of energy metabolism. The heavy utilization of glucose by the malaria…”
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Metabolic perturbations of kidney and spleen in murine cerebral malaria: (1)H NMR-based metabolomic study by Ghosh, Soumita, Sengupta, Arjun, Sharma, Shobhona, Sonawat, Haripalsingh M

“…A significant fraction of global population is under the threat of malaria. Majority of annual death is due to the more complicated form of the infection i.e…”
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Alterations in urine, serum and brain metabolomic profiles exhibit sexual dimorphism during malaria disease progression by Basant, Angika, Rege, Mayuri, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Metabolic changes in the host in response to Plasmodium infection play a crucial role in the pathogenesis of malaria. Alterations in metabolism of male and…”
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Host Responses in Malaria Disease Evaluated Through Nuclear Magnetic Resonance–Based Metabonomics by Sonawat, Haripalsingh M., PhD, Sharma, Shobhona, PhD

“…Malaria is a widespread disease caused by several species of Plasmodium. The parameters that render the hosts susceptible to severe disease complications are…”
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1H NMR metabonomics indicates continued metabolic changes and sexual dimorphism post-parasite clearance in self-limiting murine malaria model by Sengupta, Arjun, Ghosh, Soumita, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Malaria, a mosquito-borne disease caused by Plasmodium spp. is considered to be a global threat, specifically for the developing countries. In human subjects…”
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Metabolomic changes in vertebrate host during malaria disease progression by Ghosh, Soumita, Pathak, Sulabha, Sonawat, Haripalsingh M., Sharma, Shobhona, Sengupta, Arjun

“…Metabolomics refers to top-down systems biological analysis of metabolites in biological specimens. Phenotypic proximity of metabolites makes them interesting…”
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Early Perturbations in Red Blood Cells in Response to Murine Malarial Parasite Infection: Proof-of-Concept [sup.1]H NMR Metabolomic Study by Sengupta, Arjun, Ghosh, Soumita, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Background: The major focus of metabolomics research has been confined to the readily available biofluids—urine and blood serum. However, red blood cells…”
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Kinetics of salt-dependent unfolding of [2Fe-2S] ferredoxin of Halobacterium salinarum by Bandyopadhyay, Amal K, Krishnamoorthy, G, Padhy, Lakshmi C, Sonawat, Haripalsingh M

“…The [2Fe-2S] ferredoxin from the extreme haloarchaeon Halobacterium salinarum is stable in high (>1.5 M) salt concentration. At low salt concentration the…”
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Early prediction of cerebral malaria by (1)H NMR based metabolomics by Ghosh, Soumita, Sengupta, Arjun, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Cerebral malaria (CM) is a life-threatening disease, caused mainly by Plasmodium falciparum in humans. In adults only 1-2% of P. falciparum-infected hosts…”
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Liver Metabolic Alterations and Changes in Host Intercompartmental Metabolic Correlation during Progression of Malaria by Sengupta, Arjun, Basant, Angika, Ghosh, Soumita, Sharma, Shobhona, Sonawat, Haripalsingh M.

“…1H NMR-based metabonomics was used to investigate the multimodal response of mice to malarial parasite infection by P. berghei ANKA. Liver metabolism was…”
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Glycolysis in Plasmodium falciparum results in modulation of host enzyme activities by Mehta, Monika, Sonawat, Haripalsingh M, Sharma, Shobhona

“…Plasmodium falciparum, the causative agent of the most serious form of malaria, infects about 5-10% of the world human population per year. It is well…”
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Early prediction of cerebral malaria by 1H NMR based metabolomics by Ghosh, Soumita, Sengupta, Arjun, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Background Cerebral malaria (CM) is a life-threatening disease, caused mainly by Plasmodium falciparum in humans. In adults only 1-2 % of P. falciparum…”
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Global host metabolic response to Plasmodium vivax infection: a H NMR based urinary metabonomic study by Sengupta, Arjun, Ghosh, Soumita, Basant, Angika, Malusare, Suhas, Johri, Parul, Pathak, Sulabha, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Background Plasmodium vivax is responsible for the majority of malarial infection in the Indian subcontinent. This species of the parasite is generally…”
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Metabolic Perturbations of Kidney and Spleen in Murine Cerebral Malaria: 1H NMR-Based Metabolomic Study by Ghosh, Soumita, Sengupta, Arjun, Sharma, Shobhona, Sonawat, Haripalsingh M.

“…A significant fraction of global population is under the threat of malaria. Majority of annual death is due to the more complicated form of the infection i.e…”
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Metabolomic analysis of urine samples of vivax malaria in-patients for biomarker identification by Sengupta, Arjun, Ghosh, Soumita, Pathak, Sulabha, Gogtay, Nithya, Thatte, Urmilla, Doshi, Maulik, Sharma, Shobhona, Sonawat, Haripalsingh M.

“…Plasmodium vivax is the most dominating species in the Indian subcontinent among the five Plasmodium species causing malarial infection in humans. This species…”
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Multivariate modelling with (1)H NMR of pleural effusion in murine cerebral malaria by Ghosh, Soumita, Sengupta, Arjun, Sharma, Shobhona, Sonawat, Haripalsingh M

“…Cerebral malaria is a clinical manifestation of Plasmodium falciparum infection. Although brain damage is the predominant pathophysiological complication of…”
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Malaria parasite-infected erythrocytes inhibit glucose utilization in uninfected red cells by Mehta, Monika, Sonawat, Haripalsingh M., Sharma, Shobhona

“…The erythrocytic stages of the malaria parasite depend on anaerobic glycolysis for energy. Using [2- 13C]glucose and nuclear magnetic resonance, the glucose…”
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Host metabolic responses to Plasmodium falciparum infections evaluated by 1 H NMR metabolomics by Sengupta, Arjun, Ghosh, Soumita, Das, Bidyut K, Panda, Abhinash, Tripathy, Rina, Pied, Sylviane, Ravindran, B, Pathak, Sulabha, Sharma, Shobhona, Sonawat, Haripalsingh M

“…The human malarial parasite Plasmodium falciparum causes the most severe forms of malarial infections, which include cerebral malaria and various organ…”
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Salt Dependent Stability and Unfolding of [Fe2-S2] Ferredoxin of Halobacterium salinarum: Spectroscopic Investigations by Bandyopadhyay, Amal K., Sonawat, Haripalsingh M.

“…Ferredoxin from the haloarchaeon Halobacterium salinarum is a 14.6-kDa protein with a [Fe2-S2] center and is involved in the oxidative decarboxylation of…”
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