Search Results - "Son, Yeonho"
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Single-cell transcriptomic analysis reveals dynamic activation of cellular signaling pathways regulating beige adipogenesis
Published in Experimental & molecular medicine (01-10-2024)“…PDGFRA+ cells have been identified as adipocyte stem cells (ASCs) that differentiate into beige adipocytes in white adipose tissue (WAT) following thermogenic…”
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Development of CIDEA reporter mouse model and its application for screening thermogenic drugs
Published in Scientific reports (16-09-2021)“…Cell death-inducing DNA fragmentation factor-like effector A (CIDEA) is a lipid droplet-associated protein and is a known marker of the thermogenic capacity of…”
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Anti-obesity effects of heat-transformed green tea extract through the activation of adipose tissue thermogenesis
Published in Nutrition & metabolism (03-03-2022)“…Adipose tissue thermogenesis is a potential therapeutic target to increase energy expenditure and thereby combat obesity. The aim of the present study was to…”
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Adipocyte lysoplasmalogenase TMEM86A regulates plasmalogen homeostasis and protein kinase A-dependent energy metabolism
Published in Nature communications (14-07-2022)“…Dysregulation of adipose tissue plasmalogen metabolism is associated with obesity-related metabolic diseases. We report that feeding mice a high-fat diet…”
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Antiobesity effects of coumestrol through expansion and activation of brown adipose tissue metabolism
Published in The Journal of nutritional biochemistry (01-02-2020)“…Coumestrol is a dietary phytoestrogen with estrogen-mimicking characteristics. This study investigated the molecular mechanisms of antiobesity effects of…”
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MicroRNA-10a-5p regulates macrophage polarization and promotes therapeutic adipose tissue remodeling
Published in Molecular metabolism (Germany) (01-11-2019)“…This study investigated the role of microRNAs generated from adipose tissue macrophages (ATMs) during adipose tissue remodeling induced by pharmacological and…”
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Epigallocatechin-3-Gallate Reduces Visceral Adiposity Partly through the Regulation of Beclin1-Dependent Autophagy in White Adipose Tissues
Published in Nutrients (08-10-2020)“…Epigallocatechin-3-gallate (EGCG) is a primary bioactive phytochemical in green tea. Its therapeutic potential in metabolic diseases has been reported;…”
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Polymethoxyselenoflavones exert anti-obesity effects through activation of lipolysis and brown adipocyte metabolism
Published in International Journal of Obesity (01-01-2021)“…Background/objectives Polymethoxyselenoflavone (PMSF) is a compound that substitutes the oxygen atom in a flavonoid with selenium. This study aimed to…”
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Adipocyte-specific Beclin1 deletion impairs lipolysis and mitochondrial integrity in adipose tissue
Published in Molecular metabolism (Germany) (01-09-2020)“…Beclin1 is a core molecule of the macroautophagy machinery. Although dysregulation of macroautophagy is known to be involved in metabolic disorders, the…”
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Anti-Obesity Effects of Soybean Embryo Extract and Enzymatically-Modified Isoquercitrin
Published in Biomolecules (Basel, Switzerland) (30-09-2020)“…Soy isoflavones are bioactive phytoestrogens with known health benefits. Soybean embryo extract (SEE) has been consumed as a source of isoflavones, mainly…”
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Use of CIDEA Reporter Mouse Model for Screening Thermogenic Fat-Activating Drugs
Published in Methods in molecular biology (Clifton, N.J.) (2023)“…Excessive fat accumulation is a risk factor for metabolic diseases. Activating non-shivering thermogenesis in adipose tissue increases energy expenditure and…”
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Green tea extract exhibits antidiabetic effects partly through regulating dipeptidyl peptidase-4 expression in adipose tissue
Published in The Journal of nutritional biochemistry (01-01-2023)“…The antidiabetic effects of green tea have been demonstrated in clinical trials and epidemiological studies. This study investigated the antidiabetic effects…”
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Anti-obesity effects of the dual-active adenosine A2A/A3 receptor-ligand LJ-4378
Published in International Journal of Obesity (01-12-2022)“…Background and objectives A 2A adenosine receptor (A 2A AR)-mediated signaling in adipose tissues has been investigated as a potential target for…”
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TM4SF5 Knockout Protects Mice From Diet-Induced Obesity Partly by Regulating Autophagy in Adipose Tissue
Published in Diabetes (New York, N.Y.) (01-09-2021)“…Transmembrane 4 L six family member 5 (TM4SF5) functions as a sensor for lysosomal arginine levels and activates the mammalian target of rapamycin complex 1…”
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REEP6 knockout leads to defective β-adrenergic signaling in adipocytes and promotes obesity-related metabolic dysfunction
Published in Metabolism, clinical and experimental (01-05-2022)“…The mobilization and catabolism of lipid energy is a central function of adipocytes that is under the control of the β-adrenergic signaling pathway, and…”
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Integration of ZnO with g-C3N4 structures in core–shell approach via sintering process for rapid detoxification of water under visible irradiation
Published in Current applied physics (01-01-2016)“…We integrated ZnO with g-C3N4 nanostructures via successful core–shell formation using single step simple sintering process for photocatalysis application…”
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Coating 1-Octanethiol-Coated Copper Nano-Ink on a Paper Substrate via Multi-Pulse Flash Light Sintering for Application in Disposable Devices
Published in Electronic materials (Basel) (01-12-2020)“…Inkjet-printed patterns were formed on a paper substrate using anti-oxidant copper nano-ink for application to disposable electronic devices. To prevent…”
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STK3/STK4 signalling in adipocytes regulates mitophagy and energy expenditure
Published in Nature metabolism (01-03-2021)“…Obesity reduces adipocyte mitochondrial function, and expanding adipocyte oxidative capacity is an emerging strategy to improve systemic metabolism. Here, we…”
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Integration of ZnO with g-C3N4 structures in coreeshell approach via sintering process for rapid detoxification of water under visible irradiation
Published in Current applied physics (01-01-2016)“…We integrated ZnO with g-C3N4 nanostructures via successful coreeshell formation using single step simple sintering process for photocatalysis application…”
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Aging-Induced Brain-Derived Neurotrophic Factor in Adipocyte Progenitors Contributes to Adipose Tissue Dysfunction
Published in Aging and disease (01-06-2020)“…Aging-related adipose tissue dysfunction contributes to the progression of chronic metabolic diseases. We investigated the role of age-dependent expression of…”
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