Search Results - "Son, Jonghyeon"

Leucine-sensing mechanism of leucyl-tRNA synthetase 1 for mTORC1 activation by Kim, Sulhee, Yoon, Ina, Son, Jonghyeon, Park, Junga, Kim, Kibum, Lee, Ji-Ho, Park, Sam-Yong, Kang, Beom Sik, Han, Jung Min, Hwang, Kwang Yeon, Kim, Sunghoon

“…Leucyl-tRNA synthetase 1 (LARS1) mediates activation of leucine-dependent mechanistic target of rapamycin complex 1 (mTORC1) as well as ligation of leucine to…”
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Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl‐tRNA synthetase 1 by Yoon, Ina, Kim, Sulhee, Cho, Minjae, You, Kyung Ah, Son, Jonghyeon, Lee, Caroline, Suh, Ji Hun, Bae, Da‐Jeong, Kim, Jong Min, Oh, Sinae, Park, Songhwa, Kim, Sanga, Cho, Seong Hyeok, Park, Seonha, Bang, Kyuhyeon, Seo, Minjeong, Kim, Jong Hyun, Lee, Bongyong, Park, Joon Seok, Hwang, Kwang Yeon, Kim, Sunghoon

“…Prolyl‐tRNA synthetase 1 (PARS1) has attracted much interest in controlling pathologic accumulation of collagen containing high amounts of proline in fibrotic…”
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Investigating the Functional Role of the Cysteine Residue in Dehydrin from the Arctic Mouse-Ear Chickweed Cerastium arcticum by Kim, Il-Sup, Choi, Woong, Park, Ae Kyung, Kim, Hyun, Son, Jonghyeon, Lee, Jun Hyuck, Shin, Seung Chul, Kim, T Doohun, Kim, Han-Woo

“…The stress-responsive, SK subclass, dehydrin gene, , has been identified from the Arctic mouse-ear chickweed . CaDHN contains an unusual single cysteine…”
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Structural and biochemical insights into PsEst3, a new GHSR-type esterase obtained from Paenibacillus sp. R4 by Son, Jonghyeon, Choi, Woong, Kim, Hyun, Kim, Minseo, Lee, Jun Hyuck, Shin, Seung Chul, Kim, Han Woo

“…PsEst3, a psychrophilic esterase obtained from Paenibacillus sp. R4, which was isolated from the permafrost of Alaska, exhibits relatively high activity at low…”
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Structural Analysis of an Epitope Candidate of Triosephosphate Isomerase in Opisthorchis viverrini by Son, Jonghyeon, Kim, Sulhee, Kim, So Eun, Lee, Haemin, Lee, Myoung-Ro, Hwang, Kwang Yeon

“…Opisthorchis viverrini , a parasitic trematode, was recategorized as a group 1 biological carcinogen because it causes opisthorchiasis, which may result in…”
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Structural insights into a 20.8-kDa tegumental-allergen-like (TAL) protein from Clonorchis sinensis by Jo, Chang Hwa, Son, Jonghyeon, Kim, Sulhee, Oda, Takashi, Kim, Jaehoon, Lee, Myoung-Ro, Sato, Mamoru, Kim, Hyun Tae, Unzai, Satoru, Park, Sam-Yong, Hwang, Kwang Yeon

“…Survival of Clonorchis sinensis , a cause of human clonorchiasis, requires tegument proteins, which are localized to the tegumental outer surface membrane…”
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Identification, Characterization, and Preliminary X-ray Diffraction Analysis of a Single Stranded DNA Binding Protein (LjSSB) from Psychrophilic Lacinutrix jangbogonensis PAMC 27137 by Choi, Woong, Son, Jonghyeon, Park, Aekyung, Jin, Hongshi, Shin, Seung Chul, Lee, Jun Hyuck, Kim, T. Doohun, Kim, Han-Woo

“…Single-stranded DNA-binding proteins (SSBs) are essential for DNA metabolism, including repair and replication, in all organisms. SSBs have potential…”
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Structural and kinetic insights into flavin-containing monooxygenase and calponin-homology domains in human MICAL3 by Kim, Junsoo, Lee, Haemin, Roh, Yeon Jin, Kim, Han-Ul, Shin, Donghyuk, Kim, Sorah, Son, Jonghyeon, Lee, Aro, Kim, Minseo, Park, Junga, Hwang, Seong Yun, Kim, Kyunghwan, Lee, Yong Kwon, Jung, Hyun Suk, Hwang, Kwang Yeon, Lee, Byung Cheon

“…MICAL is an oxidoreductase that participates in cytoskeleton reorganization via actin disassembly in the presence of NADPH. Although three MICALs (MICAL1,…”
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Structure-based mechanism of action of a viral poly(ADP-ribose) polymerase 1-interacting protein facilitating virus replication by Chung, Woo-Chang, Kim, Junsoo, Kim, Byung Chul, Kang, Hye-Ri, Son, JongHyeon, Ki, Hosam, Hwang, Kwang Yeon, Song, Moon Jung

“…Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that modifies nuclear proteins by poly(ADP-ribosyl)ation, regulates various cellular activities and restricts…”
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Phospho‐dependent signaling during the general stress response by the atypical response regulator and ClpXP adaptor RssB by Schwartz, Jacob, Son, Jonghyeon, Brugger, Christiane, Deaconescu, Alexandra M.

“…In the model organism Escherichia coli and related species, the general stress response relies on tight regulation of the intracellular levels of the promoter…”
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EPRS1 Controls the TGF-β Signaling Pathway via Interaction with TβRI in Hepatic Stellate Cell by Yoon, Ina, Song, Ji Ae, Suh, Ji Hun, Kim, Sulhee, Son, Jonghyeon, Kim, Jong Hyun, Jang, Song Yee, Hwang, Kwang Yeon, Kim, Myung Hee, Kim, Sunghoon

“…Glutamyl-prolyl-tRNA synthetase 1 (EPRS1) is known to associated with fibrosis through its catalytic activity to produce prolyl-tRNA. Although its catalytic…”
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Crystal structure of tRNA His guanylyltransferase from Saccharomyces cerevisiae by Lee, Kitaik, Lee, Eun Hye, Son, Jonghyeon, Hwang, Kwang Yeon

“…tRNA maturation involves several steps, including processing, splicing, CCA addition, and posttranscriptional modifications. tRNA guanylyltransferase (Thg1) is…”
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Crystal structure of tRNAHis guanylyltransferase from Saccharomyces cerevisiae by Lee, Kitaik, Lee, Eun Hye, Son, Jonghyeon, Hwang, Kwang Yeon

“…tRNA maturation involves several steps, including processing, splicing, CCA addition, and posttranscriptional modifications. tRNAHis guanylyltransferase (Thg1)…”
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Conformational changes in human prolyl-tRNA synthetase upon binding of the substrates proline and ATP and the inhibitor halofuginone by Son, Jonghyeon, Lee, Eun Hye, Park, Minyoung, Kim, Jong Hyun, Kim, Junsoo, Kim, Sunghoon, Jeon, Young Ho, Hwang, Kwang Yeon

“…Aminoacyl‐tRNA synthetases recognize cognate amino acids and tRNAs from their noncognate counterparts and catalyze the formation of aminoacyl‐tRNAs…”
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The structure of the pleiotropic transcription regulator CodY provides insight into its GTP-sensing mechanism by Han, Ah-Reum, Kang, Hye-Ri, Son, Jonghyeon, Kwon, Do Hoon, Kim, Sulhee, Lee, Woo Cheol, Song, Hyun Kyu, Song, Moon Jung, Hwang, Kwang Yeon

“…GTP and branched-chain amino acids (BCAAs) are metabolic sensors that are indispensable for the determination of the metabolic status of cells. However, their…”
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Crystal structure of Legionella pneumophila type IV secretion system effector LegAS4 by Son, Jonghyeon, Jo, Chang Hwa, Murugan, Ravichandran N., Bang, Jeong Kyu, Hwang, Kwang Yeon, Lee, Woo Cheol

“…The SET domain of LegAS4, a type IV secretion system effector of Legionella pneumophila, is a eukaryotic protein motif involved in histone methylation and…”
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Essential Role of the Linker Region in the Higher Catalytic Efficiency of a Bifunctional MsrA–MsrB Fusion Protein by Han, Ah-reum, Kim, Moon-Jung, Kwak, Geun-Hee, Son, Jonghyeon, Hwang, Kwang Yeon, Kim, Hwa-Young

“…Many bacteria, particularly pathogens, possess methionine sulfoxide reductase A (MsrA) and B (MsrB) as a fusion form (MsrAB). However, it is not clear why they…”
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Screening and Genetic Network Analysis of Genes Involved in Freezing and Thawing Resistance in DaMDHAR -Expressing Saccharomyces cerevisiae Using Gene Expression Profiling by Kim, Il-Sup, Choi, Woong, Son, Jonghyeon, Lee, Jun Hyuck, Lee, Hyoungseok, Lee, Jungeun, Shin, Seung Chul, Kim, Han-Woo

“…The cryoprotection of cell activity is a key determinant in frozen-dough technology. Although several factors that contribute to freezing tolerance have been…”
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Processing of A-form ssDNA by cryptic RNase H fold exonuclease PF2046 by Kim, Junsoo, Sambalkhundev, Gerelt-Od, Kim, Sulhee, Son, Jonghyeon, Han, Ah-reum, Ko, Sul-Min, Hwang, Kwang Yeon, Lee, Woo Cheol

“…RNase H fold protein PF2046 of Pyrococcus furiosus is a 3′-5′ ssDNA exonuclease that cleaves after the second nucleotide from the 3′ end of ssDNA and prefers…”
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