Search Results - "Son, Hyo Jin"

Immunosuppressant Drugs Mitigate Immune Responses Generated by Human Mesenchymal Stem Cells Transplanted into the Mouse Parenchyma by Hwang, Jung Won, Myeong, Su Hyeon, Lee, Na-Hee, Kim, Hyeongseop, Son, Hyo Jin, Chang, Jong Wook, Lee, Na Kyung, Na, Duk L.

“…It has been widely accepted that mesenchymal stem cells (MSCs) can evade the immune surveillance of the recipient. However, emerging research cast doubt on…”
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A Novel Pyrazolo[3,4-d]pyrimidine Induces Heme Oxygenase-1 and Exerts Anti-Inflammatory and Neuroprotective Effects by Lee, Ji Ae, Kwon, Young-Won, Kim, Hye Ri, Shin, Nari, Son, Hyo Jin, Cheong, Chan Seong, Kim, Dong Jin, Hwang, Onyou

“…The anti-oxidant enzyme heme oxygenase-1 (HO-1) is known to exert anti-inflammatory effects. From a library of pyrazolo[3,4-d]pyrimidines, we identified a…”
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Impact of Circadian Nuclear Receptor REV-ERBα on Midbrain Dopamine Production and Mood Regulation by Chung, Sooyoung, Lee, Eun Jeong, Yun, Seongsik, Choe, Han Kyoung, Park, Seong-Beom, Son, Hyo Jin, Kim, Kwang-Soo, Dluzen, Dean E., Lee, Inah, Hwang, Onyou, Son, Gi Hoon, Kim, Kyungjin

“…The circadian nature of mood and its dysfunction in affective disorders is well recognized, but the underlying molecular mechanisms are still unclear. Here, we…”
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A Comparison of Immune Responses Exerted Following Syngeneic, Allogeneic, and Xenogeneic Transplantation of Mesenchymal Stem Cells into the Mouse Brain by Hwang, Jung Won, Lee, Na Kyung, Yang, Je Hoon, Son, Hyo Jin, Bang, Sa Ik, Chang, Jong Wook, Na, Duk L

“…Due to their multifactorial aspects, mesenchymal stem cells (MSCs) have been widely established as an attractive and potential candidate for the treatment of a…”
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H2S removal with an immobilized cell hybrid reactor by Son, Hyo-Jin, Lee, Jung-Heon

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A Novel Pyrazolo[3,4- d ]pyrimidine Induces Heme Oxygenase-1 and Exerts Anti-Inflammatory and Neuroprotective Effects by Lee, Ji Ae, Kwon, Young-Won, Kim, Hye Ri, Shin, Nari, Son, Hyo Jin, Cheong, Chan Seong, Kim, Dong Jin, Hwang, Onyou

“…The anti-oxidant enzyme heme oxygenase-1 (HO-1) is known to exert anti-inflammatory effects. From a library of pyrazolo[3,4- ]pyrimidines, we identified a…”
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Ethionamide Preconditioning Enhances the Proliferation and Migration of Human Wharton's Jelly-Derived Mesenchymal Stem Cells by Lee, Na-Hee, Myeong, Su Hyeon, Son, Hyo Jin, Hwang, Jung Won, Lee, Na Kyung, Chang, Jong Wook, Na, Duk L

“…Mesenchymal stem cells (MSCs) are a useful source for cell-based therapy of a variety of immune-mediated diseases, including neurodegenerative disorders…”
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Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease by Kim, Sung Tae, Son, Hyo Jin, Choi, Ji Hyun, Ji, In Jung, Hwang, Onyou

“…Abstract Parkinson's disease (PD) is caused by selective degeneration of the nigral dopaminergic (DArgic) neurons and is accompanied by motor dysfunctions such…”
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Rogdi Defines GABAergic Control of a Wake-promoting Dopaminergic Pathway to Sustain Sleep in Drosophila by Kim, Minjong, Jang, Donghoon, Yoo, Eunseok, Oh, Yangkyun, Sonn, Jun Young, Lee, Jongbin, Ki, Yoonhee, Son, Hyo Jin, Hwang, Onyou, Lee, Changwook, Lim, Chunghun, Choe, Joonho

“…Kohlschutter-Tönz syndrome (KTS) is a rare genetic disorder with neurological dysfunctions including seizure and intellectual impairment. Mutations at the…”
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Identification of potential biomarkers related to mesenchymal stem cell response in patients with Alzheimer's disease by Choi, Yejoo, Shin, Sungho, Son, Hyo Jin, Lee, Na-Hee, Myeong, Su Hyeon, Lee, Cheolju, Jang, Hyemin, Choi, Soo Jin, Kim, Hee Jin, Na, Duk L

“…Preclinical studies showed that mesenchymal stem cells (MSCs) ameliorate tau phosphorylation, amyloid-beta accumulation, and inflammation in Alzheimer's…”
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novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells by Choi, Dong Hee, Kim, Eun-Mee, Son, Hyo Jin, Joh, Tong H, Kim, Yoon Seong, Kim, Donghou, Flint Beal, M, Hwang, Onyou

“…We have previously demonstrated that the active form of matrix metalloproteinase-3 (actMMP-3) is released from dopamine(DA)rgic neurons undergoing apoptosis…”
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Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress by Kim, Eun-Mee, Shin, Eun-Jung, Choi, Ji Hyun, Son, Hyo Jin, Park, Il-Seon, Joh, Tong H., Hwang, Onyou

“…Although endoplasmic reticulum (ER) stress-induced apoptosis has been associated with pathogenesis of neurodegenerative diseases, the cellular components…”
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Syntheses of NAMDA derivatives inhibiting NO production in BV-2 cells stimulated with lipopolysaccharide by Seo, Jai Woong, Srisook, Ekaruth, Son, Hyo Jin, Hwang, Onyou, Cha, Young-Nam, Chi, Dae Yoon

“…Sixteen derivatives of NAMDA ( 1), an inhibitor of BH 4 synthesis, were designed and synthesized. Sixteen derivatives of N-acetyl-3- O-methyldopamine (NAMDA),…”
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Combination of Dexamethasone and Tofacitinib Reduces Xenogeneic MSC-Induced Immune Responses in a Mouse Model of Alzheimer’s Disease by Lee, Na Kyung, Myeong, Su Hyeon, Hwang, Jung Won, Sa, Jason K, Son, Hyo Jin, Kim, Hee Jin, Jang, Hyemin, Chang, Jong Wook, Na, Duk L

“…We have recently reported on how transplantation of human mesenchymal stem cells (MSCs) into the mouse parenchyma generated immune responses. To facilitate the…”
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A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP by Son, Hyo Jin, Lee, Ji Ae, Shin, Nari, Choi, Ji Hyun, Seo, Jai Woong, Chi, Dae Yoon, Lee, Cheol Soon, Kim, Eun‐Mee, Choe, Han, Hwang, Onyou

“…BACKGROUND AND PURPOSE In Parkinson's disease, the dopaminergic neurones in the substantia nigra undergo degeneration. While the exact mechanism for the…”
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Cytosolic labile zinc accumulation in degenerating dopaminergic neurons of mouse brain after MPTP treatment by Lee, Joo-Yong, Son, Hyo Jin, Choi, Ji Hyun, Cho, Eunsil, Kim, Jean, Chung, Sun Ju, Hwang, Onyou, Koh, Jae-Young

“…Abstract High levels of labile zinc accumulate in degenerating neurons after brain injury, such as ischemic stroke, trauma, epilepsy, and hypoglycemia…”
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Syntheses of tetrahydroisoquinoline derivatives that inhibit NO production in activated BV-2 microglial cells by Seo, Jai Woong, Srisook, Ekaruth, Son, Hyo Jin, Hwang, Onyou, Cha, Young-Nam, Chi, Dae Yoon

“…Seventeen tetrahydroisoquinoline derivatives were designed, synthesized and evaluated for inhibition of NO production in lipopolysaccharide-stimulated BV-2…”
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Matrix metalloproteinase-3 contributes to vulnerability of the nigral dopaminergic neurons by Kim, Sung Tae, Kim, Eun-Mee, Choi, Ji Hyun, Son, Hyo Jin, Ji, In Jung, Joh, Tong H., Chung, Sun Ju, Hwang, Onyou

“…Dopamine(DA)rgic neurons are particularly vulnerable due to the presence of oxidative stress-inducing molecules such as DA, tetrahydrobiopterin, iron and…”
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Assessing the Emergence and Evolution of Artificial Intelligence and Machine Learning Research in Neuroradiology by Boutet, Alexandre, Haile, Samuel S, Yang, Andrew Z, Son, Hyo Jin, Malik, Mikail, Pai, Vivek, Nasralla, Mehran, Germann, Jurgen, Vetkas, Artur, Khalvati, Farzad, Ertl-Wagner, Birgit B

“…Interest in artificial intelligence (AI) and machine learning (ML) has been growing in neuroradiology, but there is limited knowledge on how this interest has…”
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A novel pyrazolo [3,4-d] pyrimidine, KKC080106, activates the Nrf2 pathway and protects nigral dopaminergic neurons by Lee, Ji Ae, Kim, Hye Ri, Son, Hyo Jin, Shin, Nari, Han, Se Hee, Cheong, Chan Seong, Kim, Dong Jin, Hwang, Onyou

“…The transcription factor nuclear factor-erythroid 2-related factor-2 (Nrf2) is known to induce neuroprotective and anti-inflammatory effects and is considered…”
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