Search Results - "Somvanshi, Rishi K"

Somatostatin-Mediated Changes in Microtubule-Associated Proteins and Retinoic Acid–Induced Neurite Outgrowth in SH-SY5Y Cells by Paik, Seungil, Somvanshi, Rishi K., Kumar, Ujendra

“…Somatostatin (SST) is a growth hormone inhibitory peptide involved in regulation of several physiological responses of cells including neurotransmission, cell…”
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δ-opioid receptor and somatostatin receptor-4 heterodimerization: possible implications in modulation of pain associated signaling by Somvanshi, Rishi K, Kumar, Ujendra

“…Pain relief is the principal action of opioids. Somatostatin (SST), a growth hormone inhibitory peptide is also known to alleviate pain even in cases when…”
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Interaction of structure-specific and promiscuous G-protein–coupled receptors mediates small-molecule signaling in Caenorhabditis elegans by Park, Donha, O'Doherty, Inish, Somvanshi, Rishi K, Bethke, Axel, Schroeder, Frank C, Kumar, Ujendra, Riddle, Donald L

“…A chemically diverse family of small-molecule signals, the ascarosides, control developmental diapause (dauer), olfactory learning, and social behaviors of the…”
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One-pot synthesis of highly substituted imidazoles using molecular iodine: A versatile catalyst by Kidwai, Mazaahir, Mothsra, Poonam, Bansal, Vikas, Somvanshi, Rishi K., Ethayathulla, Abdul S., Dey, Sharmistha, Singh, Tej P.

“…Molecular iodine has been used as an efficient catalyst for an improved and rapid one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted…”
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Somatostatin-Mediated Regulation of Retinoic Acid-Induced Differentiation of SH-SY5Y Cells: Neurotransmitters Phenotype Characterization by Singh, Sneha, Somvanshi, Rishi K, Kumar, Ujendra

“…During brain development, neurite formation plays a critical role in neuronal communication and cognitive function. In the present study, we compared…”
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Somatostatin Ameliorates β-Amyloid-Induced Cytotoxicity via the Regulation of CRMP2 Phosphorylation and Calcium Homeostasis in SH-SY5Y Cells by Paik, Seungil, Somvanshi, Rishi K, Oliveira, Helen A, Zou, Shenglong, Kumar, Ujendra

“…Somatostatin is involved in the regulation of multiple signaling pathways and affords neuroprotection in response to neurotoxins. In the present study, we…”
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Pathophysiology of GPCR Homo- and Heterodimerization: Special Emphasis on Somatostatin Receptors by Somvanshi, Rishi K, Kumar, Ujendra

“…G-protein coupled receptors (GPCRs) are cell surface proteins responsible for translating >80% of extracellular reception to intracellular signals. The…”
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Comparative changes in breast cancer cell proliferation and signalling following somatostatin and cannabidiol treatment by Oliveira, Helen A., Somvanshi, Rishi K., Kumar, Ujendra

“…Breast cancer is the most commonly diagnosed cancer and a leading cause of cancer-related death among women worldwide. Somatostatin (SST) and Cannabinoids have…”
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C-tail mediated modulation of somatostatin receptor type-4 homo- and heterodimerizations and signaling by Somvanshi, Rishi K., Billova, Sabina, Kharmate, Geetanjali, Rajput, Padmesh S., Kumar, Ujendra

“…Somatostatin receptors show great diversity in response to agonist mediated receptor-specific homo- and heterodimerizations. Here, using…”
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Cannabinol modulates neuroprotection and intraocular pressure: A potential multi-target therapeutic intervention for glaucoma by Somvanshi, Rishi K, Zou, Shenglong, Kadhim, Salam, Padania, Sapna, Hsu, Eric, Kumar, Ujendra

“…Glaucoma is characterized by progressive damage of the retinal ganglion cells (RGCs), resulting in irreversible vision loss. Cannabinoids (CBs) ameliorate…”
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Colocalization of dopamine receptor subtypes with dopamine and cAMP-regulated phosphoprotein (DARPP-32) in rat brain by Rajput, Padmesh S., Kharmate, Geetanjali, Somvanshi, Rishi K., Kumar, Ujendra

“…In the present study using indirect immunofluorescence immunohistochemistry, co-immunoprecipitation and western blot analysis we determined the colocalization…”
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Role of somatostatin receptor 1 and 5 on epidermal growth factor receptor mediated signaling by Kharmate, Geetanjali, Rajput, Padmesh S., Watt, Heather L., Somvanshi, Rishi K., Chaudhari, Nicole, Qiu, Xiaofan, Kumar, Ujendra

“…Epidermal growth factor (EGF) regulates normal and tumor cell proliferation via epidermal growth factor receptor (EGFR) phosphorylation, homo- or…”
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Somatostatin receptor 5 is a prominent regulator of signaling pathways in cells with coexpression of Cannabinoid receptors 1 by Zou, Shenglong, Somvanshi, Rishi K, Kumar, Ujendra

“…Highlights • SSTR5 and CB1R exist as constitutive heterodimers in rat brain regions and cotransfected HEK-293 cells. • Concurrent receptor activation leads to…”
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Somatostatin Maintains Permeability and Integrity of Blood-Brain Barrier in β-Amyloid Induced Toxicity by Paik, Seungil, Somvanshi, Rishi K., Kumar, Ujendra

“…In Alzheimer’s disease (AD), the impaired clearance of β-amyloid peptide (Aβ) due to disrupted tight junction and transporter proteins is the prominent cause…”
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Regional and subcellular distribution of GABAC ρ3 receptor in brain of R6/2 mouse model of Huntington’s disease by Kumar, Ujendra, Heer, Michael, Somvanshi, Rishi K.

“…•GABAC ρ3 expression decreases in the cortex, striatum and hippocampus of HD tg mouse brain.•Loss of GABAc ρ3 receptor immunoreactivity may account for…”
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Comparative distribution of somatostatin and somatostatin receptors in PTU-induced hypothyroidism by Singh, Sneha, Somvanshi, Rishi K., Panda, Vandana, Kumar, Ujendra

“…Purpose Propylthiouracil (PTU)-induced hypothyroidism is a well-established model for assessing hormonal and morphological changes in thyroid as well as other…”
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Heterodimerization of β2 adrenergic receptor and somatostatin receptor 5: Implications in modulation of signaling pathway by Somvanshi, Rishi K, Chaudhari, Nicole, Qiu, Xiaofan, Kumar, Ujendra

“…In the present study, we describe heterodimerization between human-Somatostatin Receptor 5 (hSSTR5) and β2-Adrenergic Receptor (β2AR) and its impact on the…”
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Surface plasmon resonance studies and biochemical evaluation of a potent peptide inhibitor against cyclooxygenase-2 as an anti-inflammatory agent by Somvanshi, Rishi K., Kumar, Ashwini, Kant, Shashi, Gupta, Deepti, Singh, S. Bhaskar, Das, Utpal, Srinivasan, Alagiri, Singh, Tej P., Dey, Sharmistha

“…Cyclooxygenase (COX) is a key enzyme in the biosynthetic pathway leading to the formation of prostaglandins, which are mediators of inflammation [D.L. Dewitt,…”
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Phospholipase A2 as a Target Protein for Nonsteroidal Anti-Inflammatory Drugs (NSAIDs): Crystal Structure of the Complex Formed between Phospholipase A2 and Oxyphenbutazone at 1.6 Å Resolution by Singh, Nagendra, Jabeen, Talat, Somvanshi, Rishi K, Sharma, Sujata, Dey, Sharmistha, Singh, Tej P

“…Phospholipase A2 (PLA2; EC 3.1.1.4) is a key enzyme involved in the production of proinflammatory mediators known as eicosanoids. The binding of the substrate…”
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Characterization of somatostatin receptors and associated signaling pathways in pancreas of R6/2 transgenic mice by Somvanshi, Rishi K., Jhajj, Amrit, Heer, Michael, Kumar, Ujendra

“…The present study describes the status of somatostatin receptors (SSTRs) and their colocalization with insulin (β), glucagon (α) and somatostatin (δ) producing…”
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