Search Results - "Somogyi, A.A"

Possible involvement of toll-like receptor 4/myeloid differentiation factor-2 activity of opioid inactive isomers causes spinal proinflammation and related behavioral consequences by Hutchinson, M.R, Lewis, S.S, Coats, B.D, Rezvani, N, Zhang, Y, Wieseler, J.L, Somogyi, A.A, Yin, H, Maier, S.F, Rice, K.C, Watkins, L.R

“…Abstract Opioid-induced glial activation and its proinflammatory consequences have been associated with both reduced acute opioid analgesia and the enhanced…”
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Innate Immune Genetic Markers Predict Postoperative Morphine Consumption in an Ethnicity-Dependent Manner by Somogyi, A.A, Barratt, D.T, Tan, E.-C, Sia, A.T

“…Total patient-controlled analgesia (PCA) morphine use in the first 24 hours post-surgery was square-root transformed to a normal distribution to facilitate…”
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Pharmacokinetics and pharmacodynamics of the short-acting sedative CNS 7056 in sheep by Upton, R.N., Somogyi, A.A., Martinez, A.M., Colvill, J, Grant, C

“…CNS 7056 is a new short-acting esterase-metabolized benzodiazepine. We report the first pharmacokinetic (PK) and pharmacodynamic (PD) study of CNS 7056 and its…”
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81. Association between immune genetic markers and alcohol dependence by Coller, J.K, Hutchinson, M.R, Daly, A.K, White, J.M, Somogyi, A.A

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TLR4 haplotypes in alcohol and opioid dependent populations by Coller, J.K, Wu, Y, White, J.M, Hutchinson, M.R, Somogyi, A.A

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Potentiation of buprenorphine antinociception with ultra-low dose naltrexone in healthy subjects by Hay, J.L, La Vincente, S.F, Somogyi, A.A, Chapleo, C.B, White, J.M

“…Abstract Previous reports have demonstrated greater antinociception following administration of a buprenorphine/naloxone combination compared to buprenorphine…”
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97. Contributions of innate immune signaling to opioid & alcohol responses by Hutchinson, M.R, Wu, Y, Jaehne, E.J, Liu, L, Diener, K.R, Hayball, J.D, Rice, K.C, Watkins, L.R, Somogyi, A.A

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Opioid and alcohol action: The role of brain and spinal cord innate immune signalling by Hutchinson, M.R, Wu, Y, Liu, L, Phipps, S, Rice, K.C, Coller, J.K, Watkins, L.R, Somogyi, A.A

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Persistent postoperative pain after total knee arthroplasty: a prospective cohort study of potential risk factors by Rice, D A, Kluger, M T, McNair, P J, Lewis, G N, Somogyi, A A, Borotkanics, R, Barratt, D T, Walker, M

“…Persistent postoperative pain (PPP) is common after total knee arthroplasty (TKA). The primary aim of this prospective cohort study was to identify important…”
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High and variable population prevalence of HLA‐B56:02 in indigenous Australians and relation to phenytoin‐associated drug reaction with eosinophilia and systemic symptoms by Somogyi, Andrew A., Barratt, Daniel T., Phillips, Elizabeth J., Moore, Kylies, Ilyas, Fahmida, Gabb, Genevieve M.

“…Phenytoin drug reaction with eosinophilia and systemic symptoms (DRESS) in 3 Aboriginal Australians positive for HLA‐B*56:02 has been previously reported. We…”
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Acute pain management in opioid-tolerant patients: a growing challenge by HUXTABLE, C. A, ROBERTS, L. J, SOMOGYI, A. A, MACINTYRE, P. E

“…In Australia and New Zealand, in parallel with other developed countries, the number of patients prescribed opioids on a long-term basis has grown rapidly over…”
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Benzodiazepine dependence: focus on withdrawal syndrome by Authier, N, Balayssac, D, Sautereau, M, Zangarelli, A, Courty, P, Somogyi, A A, Vennat, B, Llorca, P-M, Eschalier, A

“…Benzodiazepines are potentially addictive drugs: psychological and physical dependence can develop within a few weeks or years of regular or repeated use. The…”
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Lack of influence of CYP2D6 genotype on the clearance of (R)-, (S)- and racemic-methadone by Coller, J K, Joergensen, C, Foster, D J R, James, H, Gillis, D, Christrup, L, Somogyi, A A

“…To investigate the influence of CYP2D6 genotype on the oral clearance of (R)-, (S)- and rac-methadone. In this retrospective study, CYP2D6 genotypes were…”
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330 BLOOD: BRAIN DISTRIBUTION OF M6G IN SHEEP by Villesen, H.H., Foster, D.J.R., Upton, R.N., Christrup, L.L., Somogyi, A.A., Martinez, A., Grant, C.

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327 CEREBRAL KINETICS OF BUPRENORPHINE AND NORBUPRENORPHINE IN CONSCIOUS SHEEP by Jensen, M.L., Foster, D.J., Upton, R.N., Grant, C., Martinez, A., Somogyi, A.A.

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Reply to Dr. Clark's comment on Doverty et al., hyperalgesic responses in methadone maintenance patients (Pain 2001;90:91–96) by Doverty, M, White, J.M, Somogyi, A.A, Bochner, F, Ali, R, Ling, W

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Acute Toxicity of 3,4-Methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti Rats by Malpass, A, White, J.M, Irvine, R.J, Somogyi, A.A, Bochner, F

“…Ingestion of MDMA (“ecstasy”) by humans can cause acute toxicity manifested by hyperthermia and death. Demethylenation of MDMA is catalyzed by cytochrome P-450…”
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Mu receptor binding of some commonly used opioids and their metabolites by Chen, Z R, Irvine, R J, Somogyi, A A, Bochner, F

“…The binding affinity to the mu receptor of some opioids chemically related to morphine and some of their metabolites was examined in rat brain homogenates with…”
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A new simple diagnostic assay for the identification of the major CYP2D6 genotypes by DNA sequencing analysis by James, H M, Coller, J K, Gillis, D, Bahnisch, J, Sallustio, B C, Somogyi, A A

“…To establish a method suitable for diagnostic genotyping of CYP2D6 alleles by DNA sequencing. Initial PCR reactions were performed to specifically amplify…”
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Determinants of withdrawal in a methadone maintenance population by White, J.M., Dyer, K.R., Bochner, F., Menelaou, A., Somogyi, A.A.

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