Search Results - "Sommermann, Erica M."
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Phase 1b Trial of Biweekly Intravenous Pexa-Vec (JX-594), an Oncolytic and Immunotherapeutic Vaccinia Virus in Colorectal Cancer
Published in Molecular therapy (01-09-2015)“…Fifteen patients with treatment-refractory colorectal cancer were enrolled on a phase 1b study of Pexa-Vec (pexastimogene devacirepvec; JX-594), an oncolytic…”
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Feedforward regulatory logic controls the specification-to-differentiation transition and terminal cell fate during Caenorhabditis elegans endoderm development
Published in Development (Cambridge) (15-06-2022)“…The architecture of gene regulatory networks determines the specificity and fidelity of developmental outcomes. We report that the core regulatory circuitry…”
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Endoderm development in Caenorhabditis elegans: The synergistic action of ELT-2 and -7 mediates the specification→differentiation transition
Published in Developmental biology (01-11-2010)“…The transition from specification of cell identity to the differentiation of cells into an appropriate and enduring state is critical to the development of…”
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Pharmacy Operationalization of the Intralesional Oncolytic Immunotherapy Talimogene Laherparepvec
Published in Hospital pharmacy (Philadelphia) (01-10-2018)“…Objective: Oncolytic immunotherapy involves the use of viruses to target and destroy cancer cells and to induce immune responses for an enhanced antitumor…”
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Essential role for Notch signaling in restricting developmental plasticity
Published in Genes & development (01-11-2012)“…We report that Notch signaling is essential for the switch from developmental plasticity to commitment during Caenorhabditis elegans embryogenesis. The GLP-1…”
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Essential role for Notch signaling in restricting developmental plasticity
Published in Genes & development (01-03-2013)Get full text
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Endoderm development in C. elegans: the synergistic action of ELT-2 and -7 mediates the specification→differentiation transition
Published in Developmental biology (31-08-2010)“…The transition from specification of cell identity to the differentiation of cells into an appropriate and enduring state is critical to the development of…”
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