Search Results - "Sommerfeld, Sven D."

Role of Inflammation and the Immune System in the Progression of Osteoarthritis by Woodell‐May, Jennifer E., Sommerfeld, Sven D.

“…ABSTRACT Understanding the molecular drivers and feedback loops of osteoarthritis (OA) may provide future therapeutic strategies to modulate the disease…”
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Proteomic composition and immunomodulatory properties of urinary bladder matrix scaffolds in homeostasis and injury by Sadtler, Kaitlyn, Sommerfeld, Sven D, Wolf, Matthew T, Wang, Xiaokun, Majumdar, Shoumyo, Chung, Liam, Kelkar, Dhanashree S, Pandey, Akhilesh, Elisseeff, Jennifer H

“…Graphical abstract…”
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Time to Relax: Mechanical Stress Release Guides Stem Cell Responses by Sommerfeld, Sven D., Elisseeff, Jennifer H.

“…Stem cells integrate spatiotemporal cues, including the mechanical properties of their microenvironment, into their fate decisions. Chaudhuri et al. (2015)…”
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Poly(NaSS) Functionalization Modulates the Conformation of Fibronectin and Collagen Type I To Enhance Osteoblastic Cell Attachment onto Ti6Al4V by Felgueiras, Helena P, Sommerfeld, Sven D, Murthy, N. Sanjeeva, Kohn, Joachim, Migonney, Véronique

“…Functionalization of surfaces with poly­(sodium styrenesulfonate) (poly­(NaSS)) has recently been found to enhance osteointegration of implantable materials…”
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Autologous Protein Solution processing alters lymphoid and myeloid cell populations and modulates gene expression dependent on cell type by Peña, Alexis N, Sommerfeld, Sven D, Anderson, Amy E, Han, Jin, Maestas, Jr, David R, Mejias, Joscelyn C, Woodell-May, Jennifer, King, William, Ganguly, Sudipto, Elisseeff, Jennifer H

“…Osteoarthritis (OA) is a degenerative disease associated with cartilage degradation, osteophyte formation, and fibrillation. Autologous Protein Solution (APS),…”
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A hyaluronic acid binding peptide-polymer system for treating osteoarthritis by Faust, Heather J., Sommerfeld, Sven D., Rathod, Sona, Rittenbach, Andrew, Ray Banerjee, Sangeeta, Tsui, Benjamin M.W., Pomper, Martin, Amzel, Mario L., Singh, Anirudha, Elisseeff, Jennifer H.

“…Hyaluronic acid (HA) is found naturally in synovial fluid and is utilized therapeutically to treat osteoarthritis (OA). Here, we employed a peptide-polymer…”
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Cyclodextrin Modulated Type I Collagen Self‐Assembly to Engineer Biomimetic Cornea Implants by Majumdar, Shoumyo, Wang, Xiaokun, Sommerfeld, Sven D., Chae, Jemin Jeremy, Athanasopoulou, Evangelia‐Nefeli, Shores, Lucas S., Duan, Xiaodong, Amzel, L. Mario, Stellacci, Francesco, Schein, Oliver, Guo, Qiongyu, Singh, Anirudha, Elisseeff, Jennifer H.

“…Collagen‐rich tissues in the cornea exhibit unique and highly organized extracellular matrix ultrastructures, which contribute to its high load‐bearing…”
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Temperature-Activated PEG Surface Segregation Controls the Protein Repellency of Polymers by Murthy, N. Sanjeeva, Wang, Wenjie, Sommerfeld, Sven D, Vaknin, David, Kohn, Joachim

“…Poly­(ethylene glycol) (PEG) is widely used to modulate the hydration states of biomaterials and is often applied to produce nonfouling surfaces. Here, we…”
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Interleukin-36γ-producing macrophages drive IL-17-mediated fibrosis by Sommerfeld, Sven D, Cherry, Christopher, Schwab, Remi M, Chung, Liam, Maestas, Jr, David R, Laffont, Philippe, Stein, Julie E, Tam, Ada, Ganguly, Sudipto, Housseau, Franck, Taube, Janis M, Pardoll, Drew M, Cahan, Patrick, Elisseeff, Jennifer H

“…Biomaterials induce an immune response and mobilization of macrophages, yet identification and phenotypic characterization of functional macrophage subsets in…”
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Structural Investigations of Polycarbonates whose Mechanical and Erosion Behavior Can Be Controlled by Their Isomer Sequence by Sommerfeld, Sven D, Murthy, N. Sanjeeva, Cohen, Jarrod, Zhang, Zheng, Kaduk, James A, Kohn, Joachim

“…One of the challenges in materials science is to design functional, synthetic polymers that match the desired properties of a specific application. Achieving…”
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Targeted delivery of hyaluronic acid to the ocular surface by a polymer-peptide conjugate system for dry eye disease by Lee, David, Lu, Qiaozhi, Sommerfeld, Sven D., Chan, Amanda, Menon, Nikhil G., Schmidt, Tannin A., Elisseeff, Jennifer H., Singh, Anirudha

“…[Display omitted] Hyaluronic acid (HA) solutions effectively lubricate the ocular surface and are used for the relief of dry eye related symptoms. However, HA…”
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Competitive Adsorption of Plasma Proteins Using a Quartz Crystal Microbalance by Felgueiras, Helena P, Murthy, N. Sanjeeva, Sommerfeld, Sven D, Brás, M. Manuela, Migonney, Véronique, Kohn, Joachim

“…Proteins that get adsorbed onto the surfaces of biomaterials immediately upon their implantation mediate the interactions between the material and the…”
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Helminth egg derivatives as proregenerative immunotherapies by Maestas, Jr, David R, Chung, Liam, Han, Jin, Wang, Xiaokun, Sommerfeld, Sven D, Kelly, Sean H, Moore, Erika, Nguyen, Helen Hieu, Mejías, Joscelyn C, Peña, Alexis N, Zhang, Hong, Hooks, Joshua S T, Chin, Alexander F, Andorko, James I, Berlinicke, Cynthia A, Krishnan, Kavita, Choi, Younghwan, Anderson, Amy E, Mahatme, Ronak, Mejia, Christopher, Eric, Marie, Woo, JiWon, Ganguly, Sudipto, Zack, Donald J, Zhao, Liang, Pearce, Edward J, Housseau, Franck, Pardoll, Drew M, Elisseeff, Jennifer H

“…The immune system is increasingly recognized as an important regulator of tissue repair. We developed a regenerative immunotherapy from the helminth soluble…”
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Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts by Sommerfeld, Sven D, Zhou, Xianyu, Mejías, Joscelyn C, Oh, Byoung Chol, Maestas, Jr, David R, Furtmüller, Georg J, Laffont, Philippe A, Elisseeff, Jennifer H, Brandacher, Gerald

“…Vascularized composite allotransplantation (VCA) is a restorative option for patients suffering from severe tissue defects not amenable to conventional…”
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Enzymatic Surface Erosion of High Tensile Strength Polycarbonates Based on Natural Phenols by Sommerfeld, Sven D, Zhang, Zheng, Costache, Marius C, Vega, Sebastián L, Kohn, Joachim

“…Surface erosion has been recognized as a valuable design tool for resorbable biomaterials within the context of drug delivery devices, surface coatings, and…”
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Cornea Implants: Cyclodextrin Modulated Type I Collagen Self‐Assembly to Engineer Biomimetic Cornea Implants (Adv. Funct. Mater. 41/2018) by Majumdar, Shoumyo, Wang, Xiaokun, Sommerfeld, Sven D., Chae, Jemin Jeremy, Athanasopoulou, Evangelia‐Nefeli, Shores, Lucas S., Duan, Xiaodong, Amzel, L. Mario, Stellacci, Francesco, Schein, Oliver, Guo, Qiongyu, Singh, Anirudha, Elisseeff, Jennifer H.

“…Corneal collagen fibrils are controlled during development by small leucine‐rich proteoglycans to create a robust, yet optically transparent tissue. In article…”
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PRELIMINARILY DEVELOPMENT OF A MOISTURE-ACTIVATED BIORESORBABLE POLYMERIC PLATFORM FOR DRUG DELIVERY by Couto, Renê O. do, Sommerfeld, Sven D., Dube, Koustubh, Freitas, Osvaldo de, Kohn, Joachim

“…Bioresorbable polymeric films were prepared by solvent casting using a tyrosine-derived polycarbonate and metronidazole (MDZ) as the model drug at 2.5%, 5% and…”
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Oriented, Multimeric Biointerfaces of the L1 Cell Adhesion Molecule: An Approach to Enhance Neuronal and Neural Stem Cell Functions on 2-D and 3-D Polymer Substrates by Cherry, Jocie F., Carlson, Aaron L., Benarba, Farah L., Sommerfeld, Sven D., Verma, Devendra, Loers, Gabriele, Kohn, Joachim, Schachner, Melitta, Moghe, Prabhas V.

“…This article focuses on elucidating the key presentation features of neurotrophic ligands at polymer interfaces. Different biointerfacial configurations of the…”
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Temperature-Activated PEG Surface Segregation Controls the Protein Repellency of Polymers by Murthy, N. Sanjeeva, Wang, Wenjie, Sommerfeld, Sven D., Vaknin, David, Kohn, Joachim

“…Poly(ethylene glycol) (PEG) is widely used to modulate the hydration states of biomaterials and is often applied to produce nonfouling surfaces. Here, we…”
Get full text