Search Results - "Sommerfeld, Mark"

In vitro metabolic and mitogenic signaling of insulin glargine and its metabolites by Sommerfeld, Mark R, Müller, Günter, Tschank, Georg, Seipke, Gerhard, Habermann, Paul, Kurrle, Roland, Tennagels, Norbert

“…Insulin glargine (Lantus) is a long-acting basal insulin analog that demonstrates effective day-long glycemic control and a lower incidence of hypoglycemia…”
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Evidence against a beneficial effect of irisin in humans by Raschke, Silja, Elsen, Manuela, Gassenhuber, Hans, Sommerfeld, Mark, Schwahn, Uwe, Brockmann, Barbara, Jung, Raphael, Wisløff, Ulrik, Tjønna, Arnt E, Raastad, Truls, Hallén, Jostein, Norheim, Frode, Drevon, Christian A, Romacho, Tania, Eckardt, Kristin, Eckel, Juergen

“…Brown adipose tissue has gained interest as a potential target to treat obesity and metabolic diseases. Irisin is a newly identified hormone secreted from…”
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Improving Downstream Process Related Manufacturability Based on Protein Engineering—A Feasibility Study by Capito, Florian, Wong, Ting Hin, Faust, Christine, Brand, Kilian, Dittrich, Werner, Sommerfeld, Mark, Tiwari, Garima, Langer, Thomas

“…ABSTRACT While bioactivity and a favorable safety profile for biotherapeutics is of utmost importance, manufacturability is also worth of consideration to ease…”
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A Therapeutic Silencing RNA Targeting Hepatocyte TAZ Prevents and Reverses Fibrosis in Nonalcoholic Steatohepatitis in Mice by Wang, Xiaobo, Sommerfeld, Mark R., Jahn‐Hofmann, Kerstin, Cai, Bishuang, Filliol, Aveline, Remotti, Helen E., Schwabe, Robert F., Kannt, Aimo, Tabas, Ira

“…Nonalcoholic steatohepatitis (NASH) is emerging as a major public health issue and is associated with significant liver‐related morbidity and mortality. At…”
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In Vitro Phosphorylation of Insulin Receptor Substrate 1 by Protein Kinase C-ζ:  Functional Analysis and Identification of Novel Phosphorylation Sites by Sommerfeld, Mark R, Metzger, Sabine, Stosik, Magdalene, Tennagels, Norbert, Eckel, Jürgen

“…Protein kinase C-ζ (PKC-ζ) participates both in downstream insulin signaling and in the negative feedback control of insulin action. Here we used an in vitro…”
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Functional studies with IgM and IgA immunoglobulins: binding to pIgR, FcαμR, FcμR, and CDC activities by Beyer, Hanna, Sommerfeld, Mark, Grandien, Kaj, Faust, Christine, Tillmann, Bodo, Leuschner, Wulf Dirk, Régnier-Vigouroux, Anne, Weil, Sandra, Rao, Ercole, Langer, Thomas

“…IgMs are the first antibodies produced by the immune system upon encounter of a possible pathogen and are one of five antibody subclasses in humans. For IgG,…”
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Comment on Wu and Spiegelman. Irisin ERKs the fat. Diabetes 2014;63:381-383 by Elsen, Manuela, Raschke, Silja, Sommerfeld, Mark, Gassenhuber, Hans, Eckel, Jürgen

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