Search Results - "Sommer, W. H."

A genetic determinant of the striatal dopamine response to alcohol in men by Ramchandani, V A, Umhau, J, Pavon, F J, Ruiz-Velasco, V, Margas, W, Sun, H, Damadzic, R, Eskay, R, Schoor, M, Thorsell, A, Schwandt, M L, Sommer, W H, George, D T, Parsons, L H, Herscovitch, P, Hommer, D, Heilig, M

“…Excessive alcohol use, a major cause of morbidity and mortality, is less well understood than other addictive disorders. Dopamine release in ventral striatum…”
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Bad habits–good goals? Meta-analysis and translation of the habit construct to alcoholism by Giannone, F., Ebrahimi, C., Endrass, T., Hansson, A. C., Schlagenhauf, F., Sommer, W. H.

“…Excessive alcohol consumption remains a global public health crisis, with millions suffering from alcohol use disorder (AUD, or simply “alcoholism”), leading…”
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Variation at the Rat Crhr1 Locus and Sensitivity to Relapse into Alcohol Seeking Induced by Environmental Stress by Hansson, A. C., Cippitelli, A., Sommer, W. H., Fedeli, A., Björk, K., Soverchia, L., Terasmaa, A., Massi, M., Heilig, M., Ciccocioppo, R.

“…Alcoholism is a chronic relapsing disorder with substantial heritability. Uncovering gene-environment interactions underlying this disease process can aid…”
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Interaction between behavioral inhibition and neural alcohol cue-reactivity in ADHD and alcohol use disorder by Vollstädt-Klein, S, Gerhardt, S, Lee, A, Strosche, A, Sharafi, G, Nuriyeva, R, Seidt, J, Hennig, O, Alm, B, Hermann, D, Sommer, WH, Kiefer, F, Luderer, M, Sobanski, E

“…Rationale Compared to the general population, adult Attention-Deficit / Hyperactivity Disorder (ADHD) is more prevalent in patients with Alcohol Use Disorder…”
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Corticosterone Actions on the Hippocampal Brain-Derived Neurotrophic Factor Expression are Mediated by Exon IV Promoter by Hansson, A. C., Sommer, W. H., Metsis, M., Strömberg, I., Agnati, L. F., Fuxe, K.

“…Brain‐derived neurotrophic factor (BDNF) expression is strongly regulated by adrenocorticosteroids via activated gluco‐ and mineralocorticoid receptors. Four…”
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Modulation of voluntary ethanol consumption by beta-arrestin 2 by Björk, K, Rimondini, R, Hansson, A.C, Terasmaa, A, Hyytiä, P, Heilig, M, Sommer, W.H

“…Beta-arrestin 2 is a multifunctional key component of the G protein-coupled receptor complex and is involved in μ-opiate and dopamine D2 receptor signaling,…”
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Optimized contrast volume for dynamic CT angiography in renal transplant patients using a multiphase CT protocol by Helck, A, Bamberg, F, Sommer, W.H, Wessely, M, Becker, C, Clevert, D.A, Notohamiprodjo, M, Reiser, M, Nikolaou, K

“…Abstract Objectives To study the feasibility of an optimized multiphase renal-CT-angiography (MP-CTA) protocol in patients with history of renal…”
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Glutathione-S-transferase expression in the brain: possible role in ethanol preference and longevity by Björk, K, Saarikoski, S.T, Arlinde, C, Kovanen, L, Osei-Hyiaman, D, Ubaldi, M, Reimers, M, Hyytiä, P, Heilig, M, Sommer, W.H

“…Identification of genes that are differentially expressed in rats bidirectionally selected for alcohol preference might reveal biological mechanisms underlying…”
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Transcription factor gene expression profiling after acute intermittent nicotine treatment in the rat cerebral cortex by Belluardo, N., Olsson, P.A., Mudo’, G., Sommer, W.H., Amato, G., Fuxe, K.

“…Several studies in different in vitro and in vivo models have demonstrated neuroprotective effects of nicotinic receptor agonists and indirect trophic actions…”
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Plasticity and impact of the central renin-angiotensin system during development of ethanol dependence by SOMMER, W. H, RIMONDINI, R, MARQUITZ, M, LIDSTRÖM, J, SIEMS, W-E, BADER, M, HEILIG, M

“…Pharmacological and genetic interference with the renin-angiotensin system (RAS) seems to alter voluntary ethanol consumption. However, understanding the…”
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Losing Control: Excessive Alcohol Seeking after Selective Inactivation of Cue-Responsive Neurons in the Infralimbic Cortex by Pfarr, Simone, Meinhardt, Marcus W, Klee, Manuela L, Hansson, Anita C, Vengeliene, Valentina, Schönig, Kai, Bartsch, Dusan, Hope, Bruce T, Spanagel, Rainer, Sommer, Wolfgang H

“…Loss of control over drinking is a key deficit in alcoholism causally associated with malfunction of the medial prefrontal cortex (mPFC), but underlying…”
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Cost-effectiveness of stress CTP versus CTA in detecting obstructive CAD or in-stent restenosis in stented patients by Kim, S. H., Rübenthaler, J., Nörenberg, D., Huber, T., Kunz, W. G., Sommer, W. H., Schoenberg, S. O., Janssen, S., Overhoff, D., Froelich, M. F.

“…Objectives The aim of this retrospective study was to determine cost-effectiveness of stress myocardial CT perfusion (CTP), coronary CT angiography (CTA), and…”
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Creating high-quality radiology reports in foreign languages through multilingual structured reporting by Sobez, L. M., Kim, S. H., Angstwurm, M., Störmann, S., Pförringer, D., Schmidutz, F., Prezzi, D., Kelly-Morland, C., Sommer, W. H., Sabel, B., Nörenberg, D., Berndt, M., Galiè, F.

“…Objectives Globalization and migration are increasing the demand for reports in different languages. We aimed to examine if structured reports created by…”
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Neurological and pulmonary adverse effects of subcutaneous methotrexate therapy by Sommer, W. H., Ganiere, V., Gachoud, D., Keta, A., Abou-Hajar, A., Dudler, J., Aujesky, D.

“…We report the case of a patient receiving subcutaneous methotrexate (MTX) treatment for rheumatoid arthritis (RA) who developed a complex pattern of…”
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Targeted overexpression of CRH receptor subtype 1 in central amygdala neurons: effect on alcohol-seeking behavior by Broccoli, L., Uhrig, S., von Jonquieres, G., Schönig, K., Bartsch, D., Justice, N. J., Spanagel, R., Sommer, W. H., Klugmann, M., Hansson, A. C.

“…Rationale The corticotropin-releasing hormone (CRH) system is a key mediator of stress-induced responses in alcohol-seeking behavior. Recent research has…”
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Reprogramming of mPFC transcriptome and function in alcohol dependence by Heilig, M., Barbier, E., Johnstone, A. L., Tapocik, J., Meinhardt, M. W., Pfarr, S., Wahlestedt, C., Sommer, W. H.

“…Despite its limited immediate reinforcement value, alcohol has a potent ability to induce neuroadaptations that promote its incentive salience, escalation of…”
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Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence by Tapocik, J D, Solomon, M, Flanigan, M, Meinhardt, M, Barbier, E, Schank, J R, Schwandt, M, Sommer, W H, Heilig, M

“…Long-term changes in brain gene expression have been identified in alcohol dependence, but underlying mechanisms remain unknown. Here, we examined the…”
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Strategies of collateral blood flow assessment in ischemic stroke: prediction of the follow-up infarct volume in conventional and dynamic CTA by Beyer, S E, Thierfelder, K M, von Baumgarten, L, Rottenkolber, M, Meinel, F G, Janssen, H, Ertl-Wagner, B, Reiser, M F, Sommer, W H

“…Collateral blood flow is an important prognostic marker in the acute stroke situation but approaches for assessment vary widely. Our aim was to compare…”
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Prediction of Stent-Retriever Thrombectomy Outcomes by Dynamic Multidetector CT Angiography in Patients with Acute Carotid T or MCA Occlusions by Thierfelder, K M, Sommer, W H, Ertl-Wagner, B, Beyer, S E, Meinel, F G, Kunz, W G, Buchholz, G, Reiser, M F, Janssen, H

“…The selection of patients for endovascular therapy is an important issue in stroke imaging. The aim of this study was to determine the predictive value of 3…”
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A gene-by-sex interaction for nicotine reward: evidence from humanized mice and epidemiology by Bernardi, R E, Zohsel, K, Hirth, N, Treutlein, J, Heilig, M, Laucht, M, Spanagel, R, Sommer, W H

“…It has been proposed that vulnerability to nicotine addiction is moderated by variation at the μ-opioid receptor locus (OPRM1), but results from human studies…”
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