Search Results - "Somji, S"

Adequacy of Hemodialysis and Its Associated Factors among Patients Undergoing Chronic Hemodialysis in Dar es Salaam, Tanzania by Somji, Samina S., Moledina, Sibtain, Ruggajo, Pascal

“…The worldwide prevalence of maintenance hemodialysis continues to rise. An adequate delivery of hemodialysis dose as measured by Kt/V or urea reduction ratio…”
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A double-blind placebo-controlled trial of azithromycin to reduce mortality and improve growth in high-risk young children with non-bloody diarrhoea in low resource settings: the Antibiotics for Children with Diarrhoea (ABCD) trial protocol by Alam, T, Ahmed, D, Ahmed, T, Chisti, M. J, Rahman, M. W, Asthana, A. K, Bansal, P. K, Chouhan, A, Deb, S, Dhingra, P, Dhingra, U, Dutta, A, Jaiswal, V. K, Kumar, J, Pandey, A, Sazawal, S, Sharma, A. K, McGrath, C, Nyabinda, C, Okello, M, Pavlinac, P. B, Singa, B, Walson, J. L, Bar-Zeev, N, Dube, Q, Freyne, B, Ndamala, C, Ndeketa, L, Badji, H, Booth, J. P, Coulibaly, F, Haidara, F, Kotloff, K, Malle, D, Mehta, A, Sow, S, Tapia, M, Tennant, S, Hotwani, A, Kabir, F, Qamar, F, Qureshi, S, Shakoor, S, Thobani, R, Yousufzai, M. T, Bakari, M, Duggan, C, Kibwana, U, Kisenge, R, Manji, K, Somji, S, Sudfeld, C, Ashorn, P, Bahl, R, De Costa, A, Simon, J

“…Acute diarrhoea is a common cause of illness and death among children in low- to middle-income settings. World Health Organization guidelines for the clinical…”
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Expression of Metallothionein Isoform 3 (MT-3) Determines the Choice between Apoptotic or Necrotic Cell Death in Cd+2-Exposed Human Proximal Tubule Cells by Somji, Seema, Garrett, Scott H., Sens, Mary Ann, Gurel, Volkan, Sens, Donald A.

“…This laboratory has shown that the third isoform of metallothionein (MT-3) is expressed in the human kidney in situ, including the cells of the proximal…”
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The Immortalized UROtsa Cell Line as a Potential Cell Culture Model of Human Urothelium by Rossi, Michael R., John R. W. Masters, Park, Seongmi, Todd, John H., Garrett, Scott H., Sens, Mary Ann, Somji, Seema, Nath, Joginder, Sens, Donald A.

“…The UROtsa cell line was isolated from a primary culture of normal human urothelium through immortalization with a construct containing the SV40 large T…”
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Differential expression of the MT-1E gene in estrogen-receptor-positive and -negative human breast cancer cell lines by Friedline, JA, Garrett, SH, Somji, S, Todd, JH, Sens, DA

“…The goal of this study was to determine which of the 10 functional metallothionein (MT) genes are expressed in four human breast cancer cell lines and whether…”
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Effect of dose reduction of supplemental zinc for childhood diarrhoea: study protocol for a double-masked, randomised controlled trial in India and Tanzania by Somji, Sarah S, Dhingra, Pratibha, Dhingra, Usha, Dutta, Arup, Devi, Prabhabati, Kumar, Jitendra, Deb, Saikat, Semwal, Om Prakash, Sazawal, Sunil, Manji, Karim, Kisenge, Rodrick, Bakari, Mohamed, Aboud, Said, Liu, Enju, Sudfeld, Christopher, Duggan, Christopher P, Ashorn, Per, Bahl, Rajiv, Simon, Jonathon L

“…BackgroundDiarrhoea-associated mortality and morbidity are highest in infants and young children in low-income and middle-income countries (LMICs). Zinc…”
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ACUTE EXPOSURE TO ARSENITE INDUCES METALLOTHIONEIN ISOFORM-SPECIFIC GENE EXPRESSION IN HUMAN PROXIMAL TUBULE CELLS by Garrett, Scott H., Belcastro, Marycharmain, Sens, Mary Ann, Somji, Seema, Sens, Donald A.

“…The expression of metallothionein (MT) mRNA and protein was determined in human proximal tubule cells (HPT) following acute exposure to the classic stimulators…”
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Metallothionein isoform 1 and 2 gene expression in the human bladder: evidence for upregulation of MT-1X mRNA in bladder cancer by Somji, S, Sens, M A, Lamm, D L, Garrett, S H, Sens, D A

“…The goals of this study were to determine the expression of metallothionein isoform 1 and 2 proteins (MT-1 and MT-2) in bladder cancer and then to determine…”
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Factors Associated with Mortality Among Hospitalized Adults with COVID-19 Pneumonia at a Private Tertiary Hospital in Tanzania: A Retrospective Cohort Study by Kassam, Nadeem, Aghan, Eric, Aziz, Omar, Mbithe, Hanifa, Hameed, Kamran, Shah, Reena, Surani, Salim, Orwa, James, Somji, Samina

“…The emergence of the novel coronavirus disease 2019 (COVID-19) has caused millions of deaths worldwide. There has been paucity of data for hospitalized African…”
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Smart Watch Detection of Supraventricular Tachycardia (SVT): First Case from Tanzania by Kassam, Nadeem, Aziz, Omar, Aghan, Eric, Somji, Samina, Mbithe, Hanifa, Bapumia, Mustafa, Mvungi, Robert, Surani, Salim

“…Smartwatches like the Apple Watch have been on the rise worldwide and their use is gaining popularity in developing countries. Their ability to detect…”
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Magnitude, Distribution and Contextual Risk Enhancing Predictors of High 10-Year Cardiovascular Risk Among Diabetic Patients in Tanzania by Kassam, Nadeem, Surani, Salim, Hameed, Kamran, Aghan, Eric, Mayenga, Robert, Matei, Iris, Jengo, Gijsberta, Bakshi, Fatma, Mbithe, Hanifa, Orwa, James, Udeani, George, Somji, Samina

“…Atherosclerotic Cardiovascular Disease (ASCVD) is the leading cause of death worldwide. In Diabetics, ASCVD is associated with poor prognosis and a higher case…”
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The Pattern of Admission, Clinical Characteristics, and Outcomes Among Patients Admitted to the Intensive Care Unit of a Tertiary Hospital in Tanzania: A 5-Year Retrospective Review by Kassam, Nadeem, Adebayo, Philip B, Matei, Iris Martin, Aghan, Eric, Somji, Samina, Kadelya, Samwel Paul, Abha, Yasson, Swai, Frank Elton, Mabusi, Mangaro, Hameed, Kamran, Mbithe, Hanifa, Thawer, Alyyah, Makakala, Mandela Charles, Bakshi, Fatma Amirali, Chuwa, Harrison, Ng'wanasayi, Masolwa, Wambura, Casmir M, Mvungi, Robert Sostenes, Orwa, James, Sharma, Munish, Udeani, George, Surani, Salim

“…Despite the implementation of complex interventions, ICU mortality remains high and more so in developing countries. The demand for critical care in…”
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Facility-based care for moderately low birthweight infants in India, Malawi, and Tanzania by Katherine E A Semrau, Rana R Mokhtar, Karim Manji, Shivaprasad S Goudar, Tisungane Mvalo, Christopher R Sudfeld, Melissa F Young, Bethany A Caruso, Christopher P Duggan, Sarah S Somji, Anne C C Lee, Mohamed Bakari, Kristina Lugangira, Rodrick Kisenge, Linda S Adair, Irving F Hoffman, Friday Saidi, Melda Phiri, Kingsly Msimuko, Fadire Nyirenda, Mallory Michalak, Sangappa M Dhaded, Roopa M Bellad, Sujata Misra, Sanghamitra Panda, Sunil S Vernekar, Veena Herekar, Manjunath Sommannavar, Rashmita B Nayak, S Yogeshkumar, Saraswati Welling, Krysten North, Kiersten Israel-Ballard, Kimberly L Mansen, Stephanie L Martin, Katelyn Fleming, Katharine Miller, Arthur Pote, Lauren Spigel, Danielle E Tuller, Linda Vesel, LIFE Study Group

“…Globally, increasing rates of facility-based childbirth enable early intervention for small vulnerable newborns. We describe health system-level inputs,…”
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Inorganic Cadmium- and Arsenite-Induced Malignant Transformation of Human Bladder Urothelial Cells by Sens, Donald A., Park, Seongmi, Gurel, Volkan, Sens, Mary Ann, Garrett, Scott H., Somji, Seema

“…Arsenic and cadmium (Cd+2) are human carcinogens, and epidemiological studies have implicated both pollutants in the development of urinary bladder cancer…”
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Urothelial Cells Malignantly Transformed by Exposure to Cadmium (Cd+2) and Arsenite (As+3) Have Increased Resistance to Cd+2 and As+3-Induced Cell Death by Somji, Seema, Zhou, Xu Dong, Garrett, Scott H., Sens, Mary Ann, Sens, Donald A.

“…This laboratory has shown that both Cd+2 and As+3 can malignantly transform human urothelial cells. The present study examined metal resistance and the…”
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Transformation of Human Urothelial Cells (UROtsa) by As super(3+) and Cd super(2+) Induces the Expression of Keratin 6a by Somji, S, Bathula, C S, Zhou, X D, Sens, MA, Sens, DA, Garrett, SH

“…Background: Cadmium and arsenite can directly and malignantly transform the UROtsa cell line. The tumor heterotransplants produced from these transformed cells…”
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Metallothionein Isoform 3 Overexpression Is Associated with Breast Cancers Having a Poor Prognosis by Sens, Mary Ann, Somji, Seema, Garrett, Scott H., Beall, C. Larry, Sens, Donald A.

“…The third isoform (MT-3) of the metallothionein gene family is unique in that it has a limited tissue distribution, is not induced by metals, has a neuronal…”
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Post-Transcriptional Regulation of Metallothionein Isoform 1 and 2 Expression in the Human Breast and the MCF-10A Cell Line by Gurel, Volkan, Sens, Donald A., Somji, Seema, Garrett, Scott H., Weiland, Tim, Sens, Mary Ann

“…Studies have shown, using immunohistochemical staining, that the MT-1 and MT-2 proteins (MT-1/2) are overexpressed in a substantial subset of ductal breast…”
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Simple Method for Identification of Metallothionein Isoforms in Cultured Human Prostate Cells by MALDI-TOF/TOF Mass Spectrometry by Wang, Rongying, Sens, Donald A, Albrecht, Amy, Garrett, Scott, Somji, Seema, Sens, Mary Ann, Lu, Xiaoning

“…The present paper describes a rapid method for identification and characterization of human metallothionein (MT) isoforms in complex cell cultures using…”
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The Unique N-Terminal Sequence of Metallothionein-3 Is Required to Regulate the Choice between Apoptotic or Necrotic Cell Death of Human Proximal Tubule Cells Exposed to Cd+2 by Somji, Seema, Garrett, Scott H., Sens, Mary Ann, Sens, Donald A.

“…This laboratory has shown that MT-3 expression determines the choice between apoptotic or necrotic cell death in Cd+2-exposed human proximal tubule cells…”
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