Search Results - "Somers, Pamela"
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Impact of Detergent-Based Decellularization Methods on Porcine Tissues for Heart Valve Engineering
Published in Annals of biomedical engineering (01-09-2016)“…To date an optimal decellularization protocol of heart valve leaflets (HVL) and pericardia (PER) with an adequate preservation of the extracellular matrix…”
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Shear stress and VEGF enhance endothelial differentiation of human adipose-derived stem cells
Published in Growth factors (Chur, Switzerland) (01-10-2014)“…Abstract Herein we combine chemical and mechanical stimulation to investigate the effects of vascular endothelial growth factor (VEGF) and physiological shear…”
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Influence of intracoronary attenuation on coronary plaque measurements using multislice computed tomography: observations in an ex vivo model of coronary computed tomography angiography
Published in European radiology (01-07-2005)“…Assessment of attenuation (measured in Hounsfield units, HU) of human coronary plaques was performed using multislice computed tomography (MSCT) in an ex vivo…”
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The Histopathology of Varicose Vein Disease
Published in Angiology (01-10-2006)“…Varicosity is a complex venous pathology affecting the lower extremities. The exact etiology and physiopathology of varicose vein disease remain, however,…”
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Role of myocardial hypertrophy on acute and chronic right ventricular performance in relation to chronic volume overload in a porcine model: Relevance for the surgical management of tetralogy of Fallot
Published in The Journal of thoracic and cardiovascular surgery (01-06-2014)“…Objectives The age for correction of tetralogy of Fallot has progressively declined to the postnatal period, often despite an increased rate of transannular…”
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Influence of convolution filtering on coronary plaque attenuation values: observations in an ex vivo model of multislice computed tomography coronary angiography
Published in European radiology (01-07-2007)“…Attenuation variability (measured in Hounsfield Units, HU) of human coronary plaques using multislice computed tomography (MSCT) was evaluated in an ex vivo…”
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Three-dimensional and quantitative analysis of atherosclerotic plaque composition by automated differential echogenicity
Published in Catheterization and cardiovascular interventions (01-12-2007)“…Objective: To validate automated and quantitative three‐dimensional analysis of coronary plaque composition using intracoronary ultrasound (ICUS). Background:…”
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Acute and Chronic Effects of Dysfunction of Right Ventricular Outflow Tract Components on Right Ventricular Performance in a Porcine Model
Published in Journal of the American College of Cardiology (03-07-2012)“…Objectives This study investigates the contribution of infundibular versus pulmonary valve (PV) dysfunction on right ventricular (RV) function in a porcine…”
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Autophagy as Mechanism for Cell Death in Degenerative Aortic Valve Disease: An Underestimated Phenomenon in Cardiovascular Diseases
Published in Autophagy (22-07-2006)“…Once degenerative aortic valve disease becomes symptomatic, valve replacement is necessary for prognostic and symptomatic reasons. In elderly patients,…”
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Autologous glue: Part of the sticky mystery unraveled
Published in The Journal of thoracic and cardiovascular surgery (01-08-2007)“…Objective The aim of the study was to evaluate the safety and efficacy of an autologous surgical tissue adhesive. Methods Autologous glue was made out of…”
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Complete Static Repopulation of Decellularized Porcine Tissues for Heart Valve Engineering: An in vitro Study
Published in Cells, tissues, organs (01-01-2017)“…To date, a completely in vitro repopulated tissue-engineered heart valve has not been developed. This study focused on sequentially seeding 2 cell populations…”
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Acute and Chronic Effects of Dysfunction of Right Ventricular Outflow Tract Components on Right Ventricular Performance in a Porcine Model: Implications for Primary Repair of Tetralogy of Fallot
Published in Journal of the American College of Cardiology (03-07-2012)“…This study investigates the contribution of infundibular versus pulmonary valve (PV) dysfunction on right ventricular (RV) function in a porcine model…”
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An optimized growth factor cocktail for ovine mesenchymal stem cells
Published in Growth factors (Chur, Switzerland) (01-02-2012)“…Growth factors that regulate proliferation, migration, and invasion of ovine mesenchymal stem cells (oMSCs) are not well defined. In this study, we have…”
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Non-Cytotoxic Crosslinkers for Heart Valve Tissue Engineering
Published in The Journal of heart valve disease (01-01-2015)“…Currently, no effective crosslinking reagents are available to treat xenogenic decellularized heart valve matrices. The study aim was to evaluate the…”
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Genipin blues: an alternative non-toxic crosslinker for heart valves?
Published in The Journal of heart valve disease (01-11-2008)“…One approach in tissue-engineering involves the implantation of decellularized, xenogenic scaffolds, with the expectation of repopulation in vivo. However, a…”
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Flexural mechanical properties of porcine aortic heart valve leaflets
Published in Journal of the mechanical behavior of biomedical materials (01-09-2012)“…Freshly excised porcine aortic heart valve cusps were subjected to a uni-axial flexural indentation test, from which the rupture characteristics and a…”
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Bioactive porcine matrices in heart valve tissue engineering
Published in The Journal of heart valve disease (01-07-2012)“…Platelet gel (PG), a storage vehicle of growth factors, can be considered for the application of growth factors in combination with mesenchymal stem cells…”
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Mechanical and chemical characteristics of an autologous glue
Published in Journal of biomedical materials research. Part A (15-09-2008)“…The study evaluates the mechanical and chemical characteristics of autologous surgical glue made by mixing ultrafiltered plasma with glutaraldehyde (GTA)…”
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Histopathology of calcific aortic valve stenosis
Published in Acta Cardiologica (01-10-2006)“…Calcific aortic valve stenosis is the most common and increasing heart valve disease in the western world. In the last 30 years, diagnosis and management were…”
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