Search Results - "Somero, George N"

Comparative physiology: a "crystal ball" for predicting consequences of global change by Somero, George N

“…Comparative physiology offers powerful approaches for developing causal, mechanistic explanations of shifts in biogeographic patterning occurring in concert…”
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Structural flexibility and protein adaptation to temperature: Molecular dynamics analysis of malate dehydrogenases of marine molluscs by Dong, Yun-wei, Liao, Ming-ling, Meng, Xian-liang, Somero, George N.

“…Orthologous proteins of species adapted to different temperatures exhibit differences in stability and function that are interpreted to reflect adaptive…”
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The Physiology of Global Change: Linking Patterns to Mechanisms by Somero, George N

“…Global change includes alterations in ocean temperature, oxygen availability, salinity, and pH, abiotic variables with strong and interacting influences on the…”
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Comparing mutagenesis and simulations as tools for identifying functionally important sequence changes for protein thermal adaptation by Liao, Ming-ling, Somero, George N., Dong, Yun-wei

“…Comparative studies of orthologous proteins of species evolved at different temperatures have revealed consistent patterns of temperature-related variation in…”
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Transcriptomic responses to salinity stress in invasive and native blue mussels (genus Mytilus) by LOCKWOOD, BRENT L., SOMERO, GEORGE N.

“…The invasive marine mussel Mytilus galloprovincialis has displaced the native congener Mytilus trossulus from central and southern California, but the native…”
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Transcriptomic responses to heat stress in invasive and native blue mussels (genus Mytilus): molecular correlates of invasive success by Lockwood, Brent L, Sanders, Jon G, Somero, George N

“…Invasive species are increasingly prevalent in marine ecosystems worldwide. Although many studies have examined the ecological effects of invasives, little is…”
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Following the heart: temperature and salinity effects on heart rate in native and invasive species of blue mussels (genus Mytilus) by Braby, Caren E, Somero, George N

“…The three species of blue mussels, Mytilus trossulus Gould 1850, M. edulis Linnaeus 1758 and M. galloprovincialis Lamarck 1819, have distinct global…”
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Tissue-specific temperature dependence of RNA editing levels in zebrafish by Li, Wenhao, Bu, Mengdi, Hu, Ruiqin, Jiang, Shouwen, Chen, Liangbiao, Somero, George N

“…RNA editing by adenosine deaminase acting on RNA (ADAR) occurs in all metazoans and fulfils several functions. Here, we examined effects of acclimation…”
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Adaptation of enzymes to temperature: searching for basic “strategies” by Somero, George N.

“…The pervasive influence of temperature on biological systems necessitates a suite of temperature—compensatory adaptations that span all levels of biological…”
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Linking biogeography to physiology: Evolutionary and acclimatory adjustments of thermal limits by Somero, George N

“…Temperature-adaptive physiological variation plays important roles in latitudinal biogeographic patterning and in setting vertical distributions along…”
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Rhythms of Gene Expression in a Fluctuating Intertidal Environment by Gracey, Andrew Y., Chaney, Maxine L., Boomhower, Judson P., Tyburczy, William R., Connor, Kwasi, Somero, George N.

“…The physiological strategies that enable organisms to thrive in habitats where environmental factors vary dramatically on a daily basis are poorly understood…”
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The cellular stress response and temperature: Function, regulation, and evolution by Somero, George N.

“…The cellular stress response (CSR) is critical for enabling organisms to cope with thermal damage to proteins, nucleic acids, and membranes. It is a graded…”
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From molecules to morphology: How food supply influences the larvae of sea urchins across all levels of biological organization by Somero, George N.

“…An important goal of many studies in molecular ecology is to utilize molecular tools to elucidate how critical traits like metabolism and growth are affected…”
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Turning a page: remaining a top competitor in an evolving publication ecosystem by Somero, George N

“…Journal of Experimental Biology (JEB) is celebrating its first 100 years this year. My own relationship with the journal spans over six decades and encompasses…”
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Hypoxia-induced Gene Expression Profiling in the Euryoxic Fish Gillichthys mirabilis by Gracey, Andrew Y., Troll, Joshua V., Somero, George N.

“…Hypoxia is important in both biomedical and environmental contexts and necessitates rapid adaptive changes in metabolic organization. Mammals, as air…”
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RNA thermosensors: how might animals exploit their regulatory potential? by Somero, George N

“…The secondary and tertiary orders of RNA structure are crucial for a suite of RNA-related functions, including regulation of translation, gene expression and…”
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The Goldilocks Principle: A Unifying Perspective on Biochemical Adaptation to Abiotic Stressors in the Sea by Somero, George N

“…The ability of marine organisms to thrive over wide ranges of environmental stressors that perturb structures of proteins, nucleic acids, and lipids…”
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Hot spots in cold adaptation: Localized increases in conformational flexibility in lactate dehydrogenase A4 orthologs of Antarctic notothenioid fishes by Fields, P A, Somero, G N

“…To elucidate mechanisms of enzymatic adaptation to extreme cold, we determined kinetic properties, thermal stabilities, and deduced amino acid sequences of…”
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New Frontiers for Organismal Biology by Kültz, Dietmar, Clayton, David F, Robinson, Gene E, Albertson, Craig, Carey, Hannah V, Cummings, Molly E, Dewar, Ken, Edwards, Scott V, Hofmann, Hans A, Gross, Louis J, Kingsolver, Joel G, Meaney, Michael J, Schlinger, Barney A, Shingleton, Alexander W, Sokolowski, Marla B, Somero, George N, Stanzione, Daniel C, Todgham, Anne E

“…Understanding how complex organisms function as integrated units that constantly interact with their environment is a long-standing challenge in biology. To…”
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Solutions: how adaptive changes in cellular fluids enable marine life to cope with abiotic stressors by Somero, George N.

“…The seas confront organisms with a suite of abiotic stressors that pose challenges for physiological activity. Variations in temperature, hydrostatic pressure,…”
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