Search Results - "Someno, Tetsuya"

A New Terrein Glucoside, a Novel Inhibitor of Angiogenin Secretion in Tumor Angiogenesis by Arakawa, Masayuki, Someno, Tetsuya, Kawada, Manabu, Ikeda, Daishiro

“…Angiogenesis is a critical step for the tumor therapy. Many angiogenic factors are involved in the tumor angiogenesis. In the course of our screening for…”
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Rubratoxin A specifically and potently inhibits protein phosphatase 2A and suppresses cancer metastasis by Wada, Shun‐ichi, Usami, Ihomi, Umezawa, Yoji, Inoue, Hiroyuki, Ohba, Shun‐ichi, Someno, Tetsuya, Kawada, Manabu, Ikeda, Daishiro

“…(Cancer Sci 2010; 101: 743–750) Although cytostatin analog protein phosphatase 2A (PP2A)‐specific inhibitors are promising candidates of a new type of…”
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Androprostamines A and B, the new anti-prostate cancer agents produced by Streptomyces sp. MK932-CF8 by Yamazaki, Yohko, Someno, Tetsuya, Igarashi, Masayuki, Kinoshita, Naoko, Hatano, Masaki, Kawada, Manabu, Momose, Isao, Nomoto, Akio

“…Androgen receptor (AR) is a validated target in all clinical states of prostate cancer. Androprostamines A and B, the new inhibitors of androgen receptor, were…”
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Quinofuracins A–E, Produced by the Fungus Staphylotrichum boninense PF1444, Show p53-Dependent Growth Suppression by Tatsuda, Daisuke, Momose, Isao, Someno, Tetsuya, Sawa, Ryuichi, Kubota, Yumiko, Iijima, Masatomi, Kunisada, Takao, Watanabe, Takumi, Shibasaki, Masakatsu, Nomoto, Akio

“…Quinofuracins A–E, novel anthraquinone derivatives containing β-d-galactofuranose that were isolated from the fungus Staphylotrichum boninense PF1444, induced…”
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New atpenins, NBRI23477 A and B, inhibit the growth of human prostate cancer cells by Kawada, Manabu, Momose, Isao, Someno, Tetsuya, Tsujiuchi, Goh, Ikeda, Daishiro

“…The growth and metastasis of prostate cancer are regulated by prostate stroma through the tumor–stromal cell interactions. Small molecules that modulate the…”
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Structure and biological properties of lentztrehalose: a novel trehalose analog by Wada, Shun-ichi, Ohba, Shun-ichi, Someno, Tetsuya, Hatano, Masaki, Nomoto, Akio

“…A new trehalose analog, lentztrehalose [4- O -(2,3-dihydroxy-3-methylbutyl)trehalose], was isolated from an actinomycete Lentzea sp. Lentztrehalose is only…”
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NBRI16716A, a new antitumor compound against human prostate cancer cells, produced by Perisporiopsis melioloides Mer-f16716 by Kawada, Manabu, Someno, Tetsuya, Inoue, Hiroyuki, Ohba, Shun-ichi, Masuda, Tohru, Kato, Taira, Ikeda, Daishiro

“…Prostate stroma can regulate the growth and metastasis of prostate cancer through the tumor–stromal cell interactions. Thus, small molecules that modulate the…”
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Citric acid inhibits a bacterial ceramidase and alleviates atopic dermatitis in an animal model by Inoue, Hiroyuki, Someno, Tetsuya, Kawada, Manabu, Ikeda, Daishiro

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Ceramidastin, a novel bacterial ceramidase inhibitor, produced by Penicillium sp. Mer-f17067 by Inoue, Hiroyuki, Someno, Tetsuya, Kato, Taira, Kumagai, Hiroyuki, Kawada, Manabu, Ikeda, Daishiro

“…Decrease of ceramide in the skin is one of the aggravating factors of atopic dermatitis. The skin is often infected by ceramidase-producing bacteria, such as…”
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NBRI17671, a new antitumor compound, produced by Acremonium sp. CR17671 by Kawada, Manabu, Usami, Ihomi, Someno, Tetsuya, Watanabe, Takumi, Abe, Hikaru, Inoue, Hiroyuki, Ohba, Shun-ichi, Masuda, Tohru, Tabata, Yuji, Yamaguchi, Sho-ichi, Ikeda, Daishiro

“…The interaction between the receptor for advanced glycation end-product (RAGE) and amphoterin has an important role in tumor growth and metastasis. Because the…”
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Inhibitory Activity of the Hypoxia-inducible Factor-1 Pathway by Tartrolone C by Yamazaki, Yohko, Someno, Tetsuya, Minamiguchi, Kazuhisa, Kawada, Manabu, Momose, Isao, Kinoshita, Naoko, Doi, Hiroyasu, Ikeda, Daishiro

“…Hypoxia-inducible factor-1 (HIF-1) is a central mediator of cellular responses to low oxygen and has recently become an important therapeutic target for solid…”
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A Microplate Assay for Selective Measurement of Growth of Epithelial Tumor Cells in Direct Coculture with Stromal Cells by KAWADA, Manabu, YOSHIMOTO, Yuya, MINAMIGUCHI, Kazuhisa, KUMAGAI, Hiroyuki, SOMENO, Tetsuya, MASUDA, Tohru, ISHIZUKA, Masaaki, IKEDA, Daishiro

“…Stromal cells play an important role in regulating epithelial malignancies through diffusible factors and adhesion. Modulation of the tumor-stromal cell…”
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Absolute Configuration of Kigamicins A, C and D by Someno, Tetsuya, Kunimoto, Setsuko, Nakamura, Hikaru, Naganawa, Hiroshi, Ikeda, Daishiro

“…The stereochemistry of kigamicins A (1), C (2) and D (3) were elucidated by a combination of X-ray crystallographic analysis and degradation studies. The…”
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Kigamicins, novel antitumor antibiotics. II. Structure determination by Kunimoto, Setsuko, Someno, Tetsuya, Yamazaki, Yohko, Lu, Jie, Esumi, Hiroyasu, Naganawa, Hiroshi

“…Kigamicin A (1), B (2), C (3), D (4) and E (5) are novel antitumor antibiotics. Their structures were determined by spectroscopic analyses including various…”
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ICM0301s, new angiogenesis inhibitors from Aspergillus sp. F-1491. I. Taxonomy, fermentation, isolation and biological activities by Kumagai, Hiroyuki, Someno, Tetsuya, Dobashi, Kazuyuki, Isshiki, Kunio, Ishizuka, Masaaki, Ikeda, Daishiro

“…In the course of screening program for inhibitors of angiogenesis, novel substances designated as ICM0301A approximately H (1 approximately 8) were isolated…”
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New Naphthoquinones, f13102A and B, from a Fungus Strain F-13102 by Yoshimoto, Yuya, Kawada, Manabu, Kumagai, Hiroyuki, Someno, Tetsuya, Inoue, Hiroyuki, Kawamura, Naoto, Isshiki, Kunio, Ikeda, Daishiro

“…Deficiency of Fas-mediated apoptosis is one of the mechanisms involved in the immune evasion by tumors. Thus, it might be a practical approach for cancer…”
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PP2A inhibitors, harzianic acid and related compounds produced by fungus strain F-1531 by Kawada, Manabu, Yoshimoto, Yuya, Kumagai, Hiroyuki, Someno, Tetsuya, Momose, Isao, Kawamura, Naoto, Isshiki, Kunio, Ikeda, Daishiro

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ICM0301s, new angiogenesis inhibitors from Aspergillus sp. F-1491. II. Physico-chemical properties and structure elucidation by Someno, Tetsuya, Kumagai, Hiroyuki, Ohba, Shun-ichi, Amemiya, Masahide, Naganawa, Hiroshi, Ishizuka, Masaaki, Ikeda, Daishiro

“…ICM0301A (1), B (2) and their congeners (3 approximately 8) were isolated from a culture broth of Aspergillus sp. F-1491 as new angiogenesis inhibitors. Their…”
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Substrate specificity of ascidian sperm trypsin-like proteases, spermosin and acrosin by Sawada, Hitoshi, Someno, Tetsuya

“…In order to investigate systematically the substrate or subsite specificity of two sperm proteases; acrosin and spermosin (a novel trypsin‐like protease) of…”
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ICM0201, a new inhibitor of osteoclastogenesis from Cunninghamella sp. F-1490. II. Structure determination and synthesis by Someno, Tetsuya, Inoue, Hiroyuki, Kumagai, Hiroyuki, Ishizuka, Masaaki, Takeuchi, Tomio

“…ICM0201 (1), a new inhibitor of murine osteoclastogenesis in culture was isolated from a fermentation broth of Cunninghamella sp. F-1490. The structure of…”
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