Search Results - "Somboro, Anou"

Diversity and Proliferation of Metallo-β-Lactamases: a Clarion Call for Clinically Effective Metallo-β-Lactamase Inhibitors by Somboro, Anou M, Osei Sekyere, John, Amoako, Daniel G, Essack, Sabiha Y, Bester, Linda A

“…The worldwide proliferation of life-threatening metallo-β-lactamase (MBL)-producing Gram-negative bacteria is a serious concern to public health. MBLs are…”
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Molecular epidemiology of antibiotic-resistant Enterococcus spp. from the farm-to-fork continuum in intensive poultry production in KwaZulu-Natal, South Africa by Molechan, Chantal, Amoako, Daniel G., Abia, Akebe Luther King, Somboro, Anou M., Bester, Linda A., Essack, Sabiha Y.

“…The poultry industry is among the main protein suppliers worldwide. Thus, this study determined the antibiotic resistance and virulence profiles of…”
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Influenza Viruses: Harnessing the Crucial Role of the M2 Ion-Channel and Neuraminidase toward Inhibitor Design by Mtambo, Sphamadla E, Amoako, Daniel G, Somboro, Anou M, Agoni, Clement, Lawal, Monsurat M, Gumede, Nelisiwe S, Khan, Rene B, Kumalo, Hezekiel M

“…As a member of the family of viruses, influenza viruses (IVs) are known causative agents of respiratory infection in vertebrates. They remain a major global…”
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Antibiotic Resistance in Staphylococcus aureus from Poultry and Poultry Products in uMgungundlovu District, South Africa, Using the "Farm to Fork" Approach by Amoako, Daniel Gyamfi, Somboro, Anou M, Abia, Akebe L K, Molechan, Chantal, Perrett, Keith, Bester, Linda A, Essack, Sabiha Y

“…This study determined the prevalence and antibiotic susceptibility profiles of isolated from selected critical control points (farm, transport, abattoir, and…”
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Multiple expansions of globally uncommon SARS-CoV-2 lineages in Nigeria by Ozer, Egon A., Simons, Lacy M., Adewumi, Olubusuyi M., Fowotade, Adeola A., Omoruyi, Ewean C., Adeniji, Johnson A., Olayinka, Oluseyi A., Dean, Taylor J., Zayas, Janet, Bhimalli, Pavan P., Ash, Michelle K., Maiga, Almoustapha I., Somboro, Anou M., Maiga, Mamoudou, Godzik, Adam, Schneider, Jeffrey R., Mamede, João I., Taiwo, Babafemi O., Hultquist, Judd F., Lorenzo-Redondo, Ramon

“…Disparities in SARS-CoV-2 genomic surveillance have limited our understanding of the viral population dynamics and may delay identification of globally…”
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1,4,7-Triazacyclononane Restores the Activity of β-Lactam Antibiotics against Metallo-β-Lactamase-Producing Enterobacteriaceae : Exploration of Potential Metallo-β-Lactamase Inhibitors by Somboro, Anou M, Amoako, Daniel G, Osei Sekyere, John, Kumalo, Hezekiel M, Khan, René, Bester, Linda A, Essack, Sabiha Y

“…Metallo-β-lactamase (MBL)-producing are of grave clinical concern, particularly as there are no metallo-β-lactamase inhibitors approved for clinical use. The…”
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Mechanistic Insights into Oxidative Stress and Apoptosis Mediated by Tannic Acid in Human Liver Hepatocellular Carcinoma Cells by Mhlanga, Priscilla, Perumal, Pearl O, Somboro, Anou M, Amoako, Daniel G, Khumalo, Hezekiel M, Khan, Rene B

“…The study investigated the cytotoxic effect of a natural polyphenolic compound Tannic acid (TA) on human liver hepatocellular carcinoma (HepG2) cells and…”
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Toxicogenicity and mechanistic pathways of aflatoxin B1 induced renal injury by Dlamini, Nomali Zanele, Somboro, Anou M., Amoako, Daniel G., Arhin, Isaiah, Khumalo, Hezekiel M., Khan, Rene B.

“…The study investigated the toxicogenic effects, molecular mechanisms and proteomic assessment of aflatoxin B1 (AFB1) on human renal cells. Hek293 cells were…”
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Rapid Diagnosis of Drug-Resistant Tuberculosis-Opportunities and Challenges by Naidoo, Kogieleum, Perumal, Rubeshan, Ngema, Senamile L, Shunmugam, Letitia, Somboro, Anou M

“…Global tuberculosis (TB) eradication is undermined by increasing prevalence of emerging resistance to available drugs, fuelling ongoing demand for more complex…”
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Understanding the Hsp90 N -terminal Dynamics: Structural and Molecular Insights into the Therapeutic Activities of Anticancer Inhibitors Radicicol (RD) and Radicicol Derivative (NVP-YUA922) by Magwenyane, Ayanda M, Mhlongo, Ndumiso N, Lawal, Monsurat M, Amoako, Daniel G, Somboro, Anou M, Sosibo, Sphelele C, Shunmugam, Letitia, Khan, Rene B, Kumalo, Hezekiel M

“…Heat shock protein 90 (Hsp90) is a crucial component in carcinogenesis and serves as a molecular chaperone that facilitates protein maturation whilst…”
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Di‐2‐picolylamine triggers caspase‐independent apoptosis by inducing oxidative stress in human liver hepatocellular carcinoma cells by Madide, Thobeka, Somboro, Anou M., Amoako, Daniel G., Khumalo, Hezekiel M., Khan, Rene B.

“…Di‐2‐picolylamine (DPA) is an organic compound that has been shown to possess antioxidant properties when conjugated to form a metal complex. The basis of this…”
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Heat Shock Protein 90 (HSP90) Inhibitors as Anticancer Medicines: A Review on the Computer-Aided Drug Discovery Approaches over the Past Five Years by Magwenyane, Ayanda M., Ugbaja, Samuel C., Amoako, Daniel G., Somboro, Anou M., Khan, Rene B., Kumalo, Hezekiel M.

“…Cancer is a disease caused by the uncontrolled, abnormal growth of cells in different anatomic sites. In 2018, it was predicted that the worldwide cancer…”
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The role of the microbiome in inflammation during tuberculosis by Somboro, Anou M., Diallo, Dramane, Holl, Jane L., Maiga, Mamoudou

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Antituberculosis Therapy and Gut Microbiota: Review of Potential Host Microbiota Directed-Therapies by Diallo, Dramane, Somboro, Anou M, Diabate, Seydou, Baya, Bacar, Kone, Amadou, Sarro, Yeya S, Kone, Bourahima, Diarra, Bassirou, Diallo, Souleymane, Diakite, Mahamadou, Doumbia, Seydou, Toloba, Yacouba, Murphy, Robert L, Maiga, Mamoudou

“…Tuberculosis (TB) remains a major public health concern with millions of deaths every year. The overlap with HIV infections, long treatment duration, and the…”
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Hematological profiles of patients with tuberculosis and nontuberculous mycobacteria infections in Bamako, Mali by Sanogo, Fanta, Kodio, Ousmane, Sarro, Yeya, Diarra, Bassirou, Coulibaly, Gagni, Tolofoudie, Mohamed, Fofana, Djeneba, Maiga, Aminata, Somboro, Anou, Diallo, Fatimata, G. Togo, Antièmé, Somboro, Amadou, Baya, Bocar, Kone, Bourahima, Sanogo, Moumine, Dabitao, Djeneba, Kone, Amadou, Diakite, Mahamadou, Doumbia, Seydou, Mamoudou, Maiga

“…Background: Pulmonary tuberculosis (TB) remains one of the main causes of morbidity and mortality in Mali. Nontuberculous mycobacteria (NTM) infections are…”
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Molecular epidemiology and genetic diversity of Mycobacterium tuberculosis complex in referral health centers of Bamako, Mali: What is new? by Kone, Bourahima, Somboro, Anou M., Kone, Mahamadou, Holl, Jane L., Baya, Bocar, Dabitao, Djeneba, Diallo, Dramane, Diarra, Bassirou, Kone, Amadou, Sarro, Yeya Dit Sadio, Sanogo, Moumine, Togo, Antieme CG, Murphy, Robert L., Diallo, Souleymane, Coulibaly, Nadie, Camara, Fatoumata, Samake, Seydou, Diakite, Mahamadou, Doumbia, Seydou, Maiga, Mamoudou

“…Tuberculosis (TB) remains an important global health issue worldwide. Despite this scourge threatening many human lives, especially in developing countries,…”
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Fluorinated Quaternary Chitosan Derivatives: Synthesis, Characterization, Antibacterial Activity, and Killing Kinetics by Cele, Zamani E.D, Somboro, Anou M, Amoako, Daniel G, Ndlandla, Lindokuhle F, Balogun, Mohammed O

“…Chitosan has become an established platform biopolymer with applications in biomedical engineering, nanomedicine, and the development of new materials with…”
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Molecular mechanisms underlying the renoprotective effects of 1,4,7-triazacyclononane: a βeta-lactamase inhibitor by Tsotetsi, Nrateng, Amoako, Daniel G., Somboro, Anou M., Khumalo, Hezekiel M., Khan, Rene B.

“…Broad-spectrum β-lactam antibiotics such as penicillin are routinely used against both Gram-negative and Gram-positive bacteria. However, bacteria that produce…”
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In Vitro Antibacterial Activity of Teixobactin Derivatives on Clinically Relevant Bacterial Isolates by Ramchuran, Estelle J, Somboro, Anou M, Abdel Monaim, Shimaa A H, Amoako, Daniel G, Parboosing, Raveen, Kumalo, Hezekiel M, Agrawal, Nikhil, Albericio, Fernando, Torre, Beatriz G de La, Bester, Linda A

“…Methicillin-resistant (MRSA) and vancomycin-resistant enterococcus (VRE) are included on the WHO high priority list of pathogens that require urgent…”
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The molecular effect of 1,4,7‐triazacyclononane on oxidative stress parameters in human hepatocellular carcinoma (HepG2) cells by Mcoyi, Simphiwe, Amoako, Daniel G., Somboro, Anou M., Khumalo, Hezekiel M., Khan, Rene B.

“…Antibiotic resistance poses a great threat to human, animal and environmental health. β‐Lactam antibiotics have been successful in combating bacterial…”
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