Search Results - "Somara, Sita"

Bioreactor Technology for Cell Therapy Manufacturing in Regenerative Medicine by Zhang, Hu, Kent, David E., Albanna, Mohammad, Lhu, Lexan, Sun, Xiuzhi Susan, Eaker, Shannon, Somara, Sita

“…Purpose of Review It is a great challenge to scale up current cell therapy processes developed in 2D systems, and bioreactor technology could play an essential…”
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Perianal implantation of bioengineered human internal anal sphincter constructs intrinsically innervated with human neural progenitor cells by Raghavan, Shreya, MSE, Miyasaka, Eiichi A., MD, Gilmont, Robert R., PhD, Somara, Sita, PhD, Teitelbaum, Daniel H., MD, Bitar, Khalil N., PhD, AGAF

“…Background The internal anal sphincter (IAS) is a major contributing factor to pressure within the anal canal and is required for maintenance of rectoanal…”
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Cytocentric measurement for regenerative medicine by Henn, Alicia D, Pereira, Taci, Hunsberger, Joshua, Mitra, Kunal, Izadifar, Zohreh, Somara, Sita, Lindström, Lisa, Forest Farb-Horch, Thomas, Boy, Jake, Muschler, George F, Bauer, Steven R, Yerden, Randy

“…Any Regenerative Medicine (RM) business requires reliably predictable cell and tissue products. Regulatory agencies expect control and documentation. However,…”
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A bacteriophage encoding a pathogenicity island, a type-IV pilus and a phage receptor in cholera bacteria by Karaolis, David K. R, Somara, Sita, Maneval, David R, Johnson, Judith A, Kaper, James B

“…The virulence properties of many pathogenic bacteria are due to proteins encoded by large gene clusters called pathogenicity islands, which are found in a…”
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Neurofibromin binds to caveolin-1 and regulates ras, FAK, and Akt by Boyanapalli, Madanamohan, Lahoud, Oscar B., Messiaen, Ludwine, Kim, Bhumsoo, Anderle de Sylor, Marianna S., Duckett, Sara J., Somara, Sita, Mikol, Daniel D.

“…Neurofibromin (Nf1) is a ∼280 kDa protein having tumor suppressor function, presumably by virtue of its GTPase activating domain, but little is known regarding…”
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MP20-16 CLINICAL TRANSLATION OF ENGINEERED PENILE TISSUE by Somara, Sita, Burnette, Teresa, Sangha, Namrata, Creahan, Lindsey, Abraha, Tsghe, Krupp, Kathryn, Stewart, Tiana, Westendorf, Torie, Damratoski, Brad, Hinshaw, Lisa, Meinecke, Todd, Hickerson, Darren, Wilkins-Port, Cynthia, Terlecki, Ryan, Yoo, James, Allickson, Julie, Atala, Anthony, Jackson, John

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MP65-01 BIOENGINEERING CORPORAL TISSUE CONSTRUCTS USING NON-HUMAN PRIMATE SMOOTH MUSCLE AND ENDOTHELIAL CELLS FOR CLINICAL APPLICATIONS by Zambon, Joao, Ju, Young Min, Williams, Koudy, Terlecki, Ryan, Somara, Sita, Jackson, John, Allickson, Julie, Yoo, James, Atala, Anthony

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Bioengineering of physiologically functional intrinsically innervated human internal anal sphincter constructs by Gilmont, Robert R, Raghavan, Shreya, Somara, Sita, Bitar, Khalil N

“…Muscle replacement for patients suffering from extensive tissue loss or dysfunction is a major objective of regenerative medicine. To achieve functional…”
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Bioengineered Internal Anal Sphincter Derived From Isolated Human Internal Anal Sphincter Smooth Muscle Cells by Somara, Sita, Gilmont, Robert R, Dennis, Robert G, Bitar, Khalil N

“…Background & Aims The internal anal sphincter (IAS) is a specialized circular smooth muscle that maintains rectoanal continence. In vitro models are needed to…”
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Successful Implantation of Bioengineered, Intrinsically Innervated, Human Internal Anal Sphincter by Raghavan, Shreya, Gilmont, Robert R, Miyasaka, Eiichi A, Somara, Sita, Srinivasan, Shanthi, Teitelbaum, Daniel H, Bitar, Khalil N

“…Background & Aims To restore fecal continence, the weakened pressure of the internal anal sphincter (IAS) must be increased. We bioengineered intrinsically…”
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PD49-07 ENGINEERING OF CORPORAL TISSUE CONSTRUCTS USING NON-HUMAN PRIMATE CORPUS CAVERNOSAL SMOOTH MUSCLE AND ENDOTHELIAL CELLS FOR CLINICAL APPLICATIONS by Zambon, Joao, Ju, Young-Min, Williams, Koudy, Terlecki, Ryan, Somara, SIta, Baume, Alexander, Dean, Ashley, Jackson, John, Allickson, Julie, Yoo, James, Atala, Anthony

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Su2034 Heat Therapy Induced Phosphorylation of HSP27 to Improve Gastrointestinal Motility by Somara, Sita, Wylie, Ashley, Kavanagh, Kylie, Bitar, Khalil N

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Distraction-Induced Intestinal Enterogenesis: Preservation of Intestinal Function and Lengthening After Reimplantation Into Normal Jejunum by KOGA, Hiroyuki, XIAOYI SUN, HUA YANG, NOSE, Keisuke, SOMARA, Sita, BITAR, Khalil N, OWYANG, Chung, OKAWADA, Manabu, TEITELBAUM, Daniel H

“…Significant bowel lengthening can occur in an isolated intestinal segment with the use of linearly directed distractive forces, resulting in increased surface…”
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Role of thin-filament regulatory proteins in relaxation of colonic smooth muscle contraction by Somara, Sita, Gilmont, Robert, Bitar, Khalil N

“…Coordinated regulation of smooth muscle contraction and relaxation is required for colonic motility. Contraction is associated with phosphorylation of myosin…”
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Peri-anal implantation of bioengineered human internal anal sphincter constructs intrinsically innervated with human neural progenitor cells by Raghavan, Shreya, Miyasaka, Eiichi A., Gilmont, Robert R., Somara, Sita, Teitelbaum, Daniel H., Bitar, Khalil N.

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Applying the Cytocentric Principles to Regenerative Medicine for Reproducibility by Henn, Alicia D., Mitra, Kunal, Hunsberger, Joshua, Sun, Xiuzhi Susan, Nardone, Mark, Montero, Ramon, Somara, Sita, Green, Gary, Blanchard, Alan, Zhang, Yu Shrike, Simon, Carl G., Yerden, Randy

“…Purpose of Review Cell and tissue products do not just reflect their present conditions; they are the culmination of all they have encountered over time…”
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Phosphorylated HSP27 modulates the association of phosphorylated caldesmon with tropomyosin in colonic smooth muscle by Somara, Sita, Bitar, Khalil N

“…Thin-filament regulation of smooth muscle contraction involves phosphorylation, association, and dissociation of contractile proteins in response to agonist…”
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Direct association of calponin with specific domains of PKC-alpha by Somara, Sita, Bitar, Khalil N

“…Calponin contributes to the regulation of smooth muscle contraction through its interaction with F-actin and inhibition of the actin-activated Mg-ATPase…”
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Phosphorylated HSP20 modulates the association of thin-filament binding proteins: caldesmon with tropomyosin in colonic smooth muscle by Somara, Sita, Gilmont, Robert R, Varadarajan, Saranyaraajan, Bitar, Khalil N

“…Small heat shock proteins HSP27 and HSP20 have been implicated in regulation of contraction and relaxation in smooth muscle. Activation of PKC-α promotes…”
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Sa2055 Neuronal Progenitor Cells Undergo Oxidant Injury Following Cryopreservation by Gilmont, Robert R, Somara, Sita, Varadarajan, Saranyaraajan, Zakhem, Elie, Raghavan, Shreya, Bitar, Khalil N

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