Search Results - "Somanchi, Anitha"
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Engineering lymph node homing of ex vivo–expanded human natural killer cells via trogocytosis of the chemokine receptor CCR7
Published in Blood (31-05-2012)“…Natural killer (NK) cells have gained significant attention in adoptive immunotherapy for cancer. Consequently, novel methods of clinical-grade expansion of NK…”
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A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry
Published in PloS one (22-10-2015)“…Natural killer (NK) cells belong to the innate arm of the immune system and though activated NK cells can modulate immune responses through the secretion of…”
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Acute Myeloid Leukemia Cells Acquire Stem Cell Features in the Bone Marrow Microenvironment
Published in Clinical lymphoma, myeloma and leukemia (01-09-2014)Get full text
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Abstract 1766: Dinutuximab targets GD2+ breast cancer stem cells and inhibits TNBC tumor growth
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Breast cancer stem-like cells (BCSCs), also known as breast cancer initiating cells, are a fraction of cells in the primary tumor that are highly…”
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Engineering Receptor Expression on Natural Killer Cells Through Trogocytosis
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2016)“…Trogocytosis is a rapid contact-dependent process by which lymphocytes acquire membrane patches from the target cells ('donor' cells) with which they interact…”
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Natural killer cells expanded on membrane-bound IL15 or IL21 activate different miRNA transcriptional profiles with functional consequences
Published in Journal for immunotherapy of cancer (04-11-2015)“…MicroRNA (miRNA) are non-coding regulatory RNA that are key posttranscriptional regulatory machinery of cells. miRNA play important role in several…”
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Acute Myeloid Leukemia Cells Acquire Chemo-Resistance By Inducing Osteoblast Differentiation in Mesenchymal Stem Cells through up-Regulation of RUNX2
Published in Blood (06-12-2014)“…The leukemia bone marrow micro-environment (BME) is comprised of the endosteal and vascular niches, provides vital support for cellular growth and conveys drug…”
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Bone Marrow Microenvironment Induces Stem Cell-Like Phenotype In Acute Myeloid Leukemia
Published in Blood (15-11-2013)“…Recent discoveries demonstrate that leukemia stem cells (LSCs) contribute towards leukemia progression and relapse. Several cell surface and intra-cellular…”
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A Novel Method for Assessment of Natural Killer Cell Cytotoxicity Using Image Cytometry: e0141074
Published in PloS one (01-10-2015)“…Natural killer (NK) cells belong to the innate arm of the immune system and though activated NK cells can modulate immune responses through the secretion of…”
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Proteomic, Gene Expression, and Micro-RNA Analysis Of Bone Marrow Mesenchymal Stromal Cells In Acute Myeloid Leukemia Identifies Pro-Inflammatory, Pro-Survival Signatures In Vitro and In Vivo
Published in Blood (15-11-2013)“…The bone marrow microenvironment (BME) in acute myeloid leukemia (AML) generates resistance signals that protect AML cells/stem cells from chemotherapy. The…”
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