Search Results - "Soma, Masaaki"

Orally administered eicosapentaenoic acid reduces and stabilizes atherosclerotic lesions in ApoE-deficient mice by Matsumoto, Miwa, Sata, Masataka, Fukuda, Daiju, Tanaka, Kimie, Soma, Masaaki, Hirata, Yasunobu, Nagai, Ryozo

“…Abstract Accumulating evidence demonstrates that dietary intake of n -3 polyunsaturated fatty acids (PUFAs) is associated with reduced incidence of…”
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Oral eicosapentaenoic acid supplementation as possible therapy for endometriosis by Netsu, Sachiho, M.D, Konno, Ryo, M.D., Ph.D, Odagiri, Kohei, M.D, Soma, Masaaki, Ph.D, Fujiwara, Hiroyuki, M.D., Ph.D, Suzuki, Mitsuaki, M.D., Ph.D

“…Objective To investigate the anti-inflammatory effect of n-3 eicosapentaenoic acid (EPA) compared with n-6 linoleic acid (LA) in an endometriosis rat model. We…”
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Eicosapentaenoic acid increases cytochrome P-450 2J2 gene expression and epoxyeicosatrienoic acid production via peroxisome proliferator-activated receptor γ in endothelial cells by Wang, Dahai, MD, PhD, Hirase, Tetsuaki, MD, PhD, Nitto, Takeaki, PhD, Soma, Masaaki, PhD, Node, Koichi, MD, PhD, FJCC

“…Summary ω-3 fatty acids, such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have beneficial effects on cardiovascular diseases. Cytochrome…”
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Inhibitory effects of eicosapentaenoic acid on chronic cerebral vasospasm after subarachnoid hemorrhage: possible involvement of a sphingosylphosphorylcholine-rho-kinase pathway by Shirao, Satoshi, Fujisawa, Hirosuke, Kudo, Akira, Kurokawa, Tetsu, Yoneda, Hiroshi, Kunitsugu, Ichiro, Ogasawara, Kuniaki, Soma, Masaaki, Kobayashi, Sei, Ogawa, Akira, Suzuki, Michiyasu

“…Rho-kinase (ROK)-mediated Ca2+ sensitization of vascular smooth muscle (VSM) contraction plays a pivotal role in cerebral vasospasm (CV). We previously…”
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Elevated concentrations of sphingosylphosphorylcholine in cerebrospinal fluid after subarachnoid hemorrhage: A possible role as a spasmogen by Kurokawa, Tetsu, Yumiya, Yasunobu, Fujisawa, Hirosuke, Shirao, Satoshi, Kashiwagi, Shiro, Sato, Masafumi, Kishi, Hiroko, Miwa, Saori, Mogami, Kimiko, Kato, Shoichi, Akimura, Tatsuo, Soma, Masaaki, Ogasawara, Kuniaki, Ogawa, Akira, Kobayashi, Sei, Suzuki, Michiyasu

“…Abstract This study investigates the role of sphingosylphosphorylcholine (SPC) in the mechanisms underlying cerebral vasospasm after subarachnoid hemorrhage…”
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Stabilizing effects of eicosapentaenoic acid on Kv1.5 channel protein expressed in mammalian cells by Koshida, Shunya, Kurata, Yasutaka, Notsu, Tomomi, Hirota, Yutaka, Kuang, Ting Y., Li, Peili, Bahrudin, Udin, Harada, Shingo, Miake, Junichiro, Yamamoto, Yasutaka, Hoshikawa, Yoshiko, Igawa, Osamu, Higaki, Katsumi, Soma, Masaaki, Yoshida, Akio, Ninomiya, Haruaki, Shiota, Goshi, Shirayoshi, Yasuaki, Hisatome, Ichiro

“…We investigated the effects of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on the stability of Kv1.5 channel protein. The expression and…”
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Acute and chronic effects of eicosapentaenoic acid on voltage-gated sodium channel expressed in cultured human bronchial smooth muscle cells by Jo, Taisuke, Iida, Haruko, Kishida, Shinya, Imuta, Hiroyuki, Oonuma, Hitoshi, Nagata, Taiji, Hara, Hajime, Iwasawa, Kuniaki, Soma, Masaaki, Sato, Yoshiaki, Nagase, Takahide, Nagai, Ryozo, Nakajima, Toshiaki

“…This study investigated acute and chronic effects of eicosapentaenoic acid (EPA) on voltage-gated Na + current ( I Na) expressed in cultured human bronchial…”
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Eicosapentaenoic Acid Suppresses Basal and Insulin-Stimulated Endothelin-1 Production in Human Endothelial Cells by CHISAKI, Keigo, OKUDA, Yukichi, SUZUKI, Seiji, MIYAUCHI, Takashi, SOMA, Masaaki, OHKOSHI, Norio, SONE, Hirohito, YAMADA, Nobuhiro, NAKAJIMA, Toshiaki

“…cis-Polyunsaturated fatty acids such as eicosapentaenoic acid (EPA) are the major fatty acids contained in fish oil, and are known to affect the various…”
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Fetus-specific expression of a form of cytochrome P-450 in human livers by Komori, Masayuki, Nishio, Kanako, Kitada, Mitsukazu, Shiramatsu, Koji, Muroya, Kozou, Soma, Masaaki, Nagashima, Kazuo, Kamataki, Tutsuya

“…The developmentally regulated expression of forms of cytochrome P-450, namely, those encoded by lambda HFL33 and NF25 or HLp cDNAs, which were isolated from…”
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Eicosapentaenoic acid reduces myocardial injury induced by ischemia and reperfusion in rabbit hearts by OGITA, Hisakazu, NODE, Koichi, ASANUMA, Hiroshi, SANADA, Shoji, TAKASHIMA, Seiji, MINAMINO, Tetsuo, SOMA, Masaaki, KIM, Jiyoong, HORI, Masatsugu, KITAKAZE, Masafumi

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Influence of cellular incorporation of n-3 eicosapentaenoic acid on intracellular Ca2+ concentration and membrane potential in vascular smooth muscle cells by ASANO, M, NAKAJIMA, T, YAMASHITA, K, OKUDA, Y, HAZAMA, H, IWASAWA, K, TOMARU, T, OMATA, M, SOMA, M, ASAKURA, Y, MIZUTANI, M, SUZUKI, S

“…Long-term treatment with n-3 eicosapentaenoic acid (EPA) has been shown to exert hypotensive effects and have beneficial effects on atherosclerosis. To…”
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Cholesterol Primes Vascular Smooth Muscle to Induce Ca2+ Sensitization Mediated by a Sphingosylphosphorylcholine–Rho-Kinase Pathway: Possible Role for Membrane Raft by Morikage, Noriyasu, Kishi, Hiroko, Sato, Masafumi, Guo, Fengling, Shirao, Satoshi, Yano, Takashi, Soma, Masaaki, Hamano, Kimikazu, Esato, Kensuke, Kobayashi, Sei

“…Hypercholesterolemia is a major risk factor involved in abnormal cardiovascular events. Rho-kinase–mediated Ca sensitization of vascular smooth muscle (VSM)…”
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Eicosapentaenoic acid prevents endothelin-1-induced cardiomyocyte hypertrophy in vitro through the suppression of TGF-beta 1 and phosphorylated JNK by Shimojo, Nobutake, Jesmin, Subrina, Zaedi, Sohel, Maeda, Seiji, Soma, Masaaki, Aonuma, Kazutaka, Yamaguchi, Iwao, Miyauchi, Takashi

“…The cardiovascular benefit of fish oil in humans and experimental animals has been reported. Endothelin (ET)-1 is a well-known cardiac hypertrophic factor…”
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A monoclonal antibody (MSN-1) against a newly established uterine endometrial cancer cell line (SNG-II) and its application to immunohistochemistry and flow cytometry by Nozawa, S, Sakayori, M, Ohta, K, Iizuka, R, Mochizuki, H, Soma, M, Fujimoto, J, Hata, J, Iwamori, M, Nagai, Y

“…To determine a phenotypic difference between normal endometrium and endometrial adenocarcinoma, a new monoclonal antibody (MSN-1) was produced by immunizing a…”
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Abstract 3660: Cardioprotective Effect of Eicosapentaenoic Acid, an Important Fish Oil, through Suppression of Endothelin-1-induced Cardiomyocyte Hypertrophy via PPAR-α by Shimojo, Nobutake, Jesmin, Subrina, Soma, Masaaki, Maeda, Seiji, Miyauchi, Takashi, Aonuma, Kazutaka

“…Abstract only A growing body of evidences report the cardiovascular benefit of fish oil including eicosapentaenoic acid (EPA) in humans and experimental…”
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Oral eicosapentaenoic acid supplementation as possible therapy for endometriosis: Reproductive Biology by NETSU, Sachiho, KONNO, Ryo, ODUGIRI, Kohei, SOMA, Masaaki, FUJIWARA, Hiroyuki, SUZUKI, Mitsuaki

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EPA effect on NOS gene expression and on NO level in endothelin-1-induced hypertrophied cardiomyocytes by Shimojo, Nobutake, Jesmin, Subrina, Zaedi, Sohel, Soma, Masaaki, Kobayashi, Tsutomu, Maeda, Seiji, Yamaguchi, Iwao, Goto, Katsutoshi, Miyauchi, Takashi

“…Cardiomyocytes release (or metabolize) several diffusible agents (e.g., nitric oxide [NO], endothelin-1 [ET-1], and angiotensin II) that exert direct effects…”
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Changes in important apoptosis-related molecules in the endothelin-1-induced hypertrophied cardiomyocytes: effect of the pretreatment with eicosapentaenoic Acid by Shimojo, Nobutake, Jesmin, Subrina, Zaedi, Sohel, Soma, Masaaki, Maeda, Seiji, Yamaguchi, Iwao, Goto, Katsutoshi, Miyauchi, Takashi

“…Human heart failure is preceded by a process called cardiac remodeling, in which heart chambers progressively enlarge and contractile function deteriorates…”
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Cholesterol Primes Vascular Smooth Muscle to Induce Ca 2 Sensitization Mediated by a Sphingosylphosphorylcholine–Rho-Kinase Pathway: Possible Role for Membrane Raft by Morikage, Noriyasu, Kishi, Hiroko, Sato, Masafumi, Guo, Fengling, Shirao, Satoshi, Yano, Takashi, Soma, Masaaki, Hamano, Kimikazu, Esato, Kensuke, Kobayashi, Sei

“…Hypercholesterolemia is a major risk factor involved in abnormal cardiovascular events. Rho-kinase–mediated Ca 2+ sensitization of vascular smooth muscle (VSM)…”
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Cholesterol Primes Vascular Smooth Muscle to Induce Ca super(2) Sensitization Mediated by a Sphingosylphosphorylcholine-Rho-Kinase Pathway: Possible Role for Membrane Raft by Morikage, Noriyasu, Kishi, Hiroko, Sato, Masafumi, Guo, Fengling, Shirao, Satoshi, Yano, Takashi, Soma, Masaaki, Hamano, Kimikazu, Esato, Kensuke, Kobayashi, Sei

“…Hypercholesterolemia is a major risk factor involved in abnormal cardiovascular events. Rho-kinase-mediated Ca super(2+) sensitization of vascular smooth…”
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