Ophthalmic and Neuro-ophthalmic Manifestations of Coronavirus Disease 2019 (COVID-19)

To describe a case of inflammatory chorioretinopathy and Adie's syndrome possibly associated with COVID-19. Observational case report. A 51-year-old woman developed fever, cough, and headache followed by retro-ocular pain and reading impairment. She tested positive for SARS-COV-2 infection by q...

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Bibliographic Details
Published in:	Ocular immunology and inflammation Vol. 28; no. 8; pp. 1285 - 1289
Main Authors:	Ortiz-Seller, Amparo, Martínez Costa, Lucía, Hernández-Pons, Antonio, Valls Pascual, Elia, Solves Alemany, Alicia, Albert-Fort, Mara
Format:	Journal Article
Language:	English
Published:	England Taylor & Francis 16-11-2020
Subjects:	Adie Syndrome - diagnosis Adie Syndrome - etiology Adie's pupil Betacoronavirus Coronavirus Infections - complications Coronavirus Infections - epidemiology COVID-19 Female Fluorescein Angiography Fundus Oculi Humans inflammatory chorioretinopathy Middle Aged multimodal imaging ophthalmic manifestation Pandemics Pneumonia, Viral - complications Pneumonia, Viral - epidemiology SARS-CoV-2 Tomography, Optical Coherence Visual Acuity COVID-19 inflammatory chorioretinopathy ophthalmic manifestation Adie’s pupil multimodal imaging
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Summary:	To describe a case of inflammatory chorioretinopathy and Adie's syndrome possibly associated with COVID-19. Observational case report. A 51-year-old woman developed fever, cough, and headache followed by retro-ocular pain and reading impairment. She tested positive for SARS-COV-2 infection by qualitative real-time reverse-transcriptase-polymerase-chain-reaction. The slit-lamp and funduscopic exam revealed abnormal pupillary response and yellowish creamy deep chorioretinal lesions, which were not present in previous examinations. Instillation of pilocarpine demonstrated denervation supersensitivity, and it was suggestive of bilateral Adie tonic pupil. A comprehensive work-up ruled out other systemic, autoimmune, or infectious diseases. This case illustrates the possible association between multifocal chorioretinitis and Adie's syndrome, and the SARS-COV-2 infection in humans. Further investigation of virus infectivity specifically within ocular tissues has to be conducted.
Bibliography:	ObjectType-Case Study-3 SourceType-Scholarly Journals-1 content type line 23 ObjectType-Feature-5 ObjectType-Undefined-1 ObjectType-Report-2 ObjectType-Article-4
ISSN:	0927-3948 1744-5078
DOI:	10.1080/09273948.2020.1817497